Author Topic: Could POIS be hyperammonia?  (Read 1914 times)


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Re: Could POIS be hyperammonia?
« Reply #20 on: October 25, 2023, 08:07:54 AM »

"The combination of L-ornithine and L-aspartate (LOLA) lowers the level of ammonia in a person's blood.[24] Very weak evidence from clinical trials indicates that LOLA treatment may benefit people with hepatic encephalopathy.[24] LOLA lowers ammonia levels by increasing the generation of urea through the urea cycle, a metabolic pathway that removes ammonia by turning it into the neutral substance urea.[25] LOLA may be combined with lactulose and/or rifaximin if these alone are ineffective at controlling symptoms."