Hello everyone, I hope you are doing well!
I was asked by Dr. Irwin Goldstein of San Diego Sexual Medicine (SDSM) to share slides that he uses to discuss POIS with his patients. Most of the slides were used by Dr. Barry Komisaruk in a women’s sexual health meeting. The POIS definition slide and a slide that includes medications considered for POIS were the only POIS slides. The rest of the slides were mainly used for Persistent Genital Arousal Disorder (PGAD)/Genito-Pelvic Dysesthesia (GPD) and I thought some of the information could be useful for POIS research. Dr. Goldstein brings them up to POIS patients to show how radiculopathy of the spine can cause sexual medicine disorders like PGAD/GPD and possibly even POIS. Basically, SDSM is relating POIS to the spine. I asked a question to Dr. Komisaruk if slide #8 and #9 showed women’s brain activity. I will post his answers below the proper slides! I am not promoting or soliciting for SDSM or anyone!
CAUTION: Slide #10 shows an image of a real-life Tarlov cyst during a surgical procedure!
NOTE!: A TFESI procedure for a POIS patient on the spine to specifically target the hypothesized disc abnormality would be highly unethical. Much more research would be needed to prove the safety and effectiveness of any procedure targeting the POIS patient's hypothesized disc abnormality or involvement in POIS. In my opinion, it would be much more propitious to avoid any procedure like the TFESI, lumbar back surgery, chiropractic adjustment and even physical therapy/contrast therapy to specifically target the hypothesized disc abnormality as a POIS treatment until much more data can be gathered to find safer and more appropriate treatment options.
I have already called San Diego Sexual Medicine to discontinue the TFESI and have emailed Dr. Goldstein to stop providing it. If Dr. Goldstein, Dr. Barry Komisaruk, or any other medical provider offers it, please kindly reject it.
I highly suggest that you attempt to treat your POIS with safer and healthier options like the one below here as research is gathered:
https://poiscenter.com/forums/index.php?topic=2338.01. POIS Definition
“Post orgasmic illness syndrome (POIS) is characterized by peripheral and/or central aversive symptoms that occur before, during, or after orgasm not related to a compromise of orgasm quality. Central aversive symptoms can include disorientation, confusion, impaired judgment, decreased verbal memory, anxiety, insomnia, depression, seizures, and/or headache. Peripheral aversive symptoms can include diarrhea, constipation, muscle aches, abdominal pain, diaphoresis, chills, hot flashes, fatigue, akathisia, and genital pain. Such orgasm-associated symptoms can last for minutes, hours, or days after orgasm and can vary widely.”
2. Clitoris touch and Genito-Pelvic Dysesthesia (GPD)/Persistent Genital Arousal Disorder (GPAD)
3. Parts of the brain
4.Perception of sensation of genital arousal
5. Role of the cauda equina
6. Radiculopathy of the SSNR in the lumbar region
7.Radiculopathy of the SSNR in the sacral region
8.Brain blood flow before, during, and after orgasm
“The nice composite slide of 12 images is my functional MRI data of an orgasm in one woman in response to clitoral self-stimulation. It uses a “hot metal” analog color in which darkest red is lowest activity then red then light red then orange then yellow then white “hot” is the highest relative activity. The self-stimulation starts at the upper left then goes across, then down to the next row showing orgasm going across then down to the lowest row showing the end of orgasm and cooling down.”
9.Brain regions activated at orgasm (Anzelotti)
“One slide is the Anzellotti epileptic focus and brain connectivity on top and our orgasm in women data from our JSM paper”
“Anzellotti is not showing orgasm. The point of that slide is that in their single case study, the woman reported that her epileptic seizures feel like orgasms. Their analysis of increased connectivity among the blue brain regions connected by green lines in that woman is consistent with the same brain regions that we found are activated by normal orgasms (group data of 11 women’s orgasms).”
Anzellotti research
paper:
https://www.sciencedirect.com/science/article/abs/pii/S0306452210000989?via%3Dihub JSM Paper:
https://www.jsm.jsexmed.org/article/S1743-6095(17)31396-6/abstract10.A tarlov cyst
Here is more information regarding the relation of the spine to PGAD/GPD:
https://youtu.be/m2BmjvI2ZeU11. Medications considered for POIS and perhaps for other sexual medicine condition
Safety Note:These medications were considered for POIS and perhaps for other sexual medicine conditions. These medications are usually prescription only and will need medical supervision under a doctor. Only 2 of these medications: Clonazepam and Topiramate, were prescribed by Dr. Goldstein. As for how well they work against POIS, I am not entirely sure and you would have to contact SDSM about it.
Thanks for reading and stay safe everyone!
