Warrior's Journal (My POIS Protocol)

[Warrior]

how to use glycine and niacin?, should I use both, like first take some glycine to stop the methylation and then take niacin every 1/2 hour to eliminate excess methyl groups?

Why do you want to take them?

Only needed if suffering from over-methylation.

I'm not a doctor but thats what is typically advised in methylation community.

[quiteQuiet]

Hey man,
good to hear you are doing better than a year ago as you say.
Can I ask, since you are quite knowledgable on this, do you know about licorice?
I read about it somewhere that it is very important for overcoming pois and had brought it but I don't feel any difference after taking it. I'm wondering what that means as it relates to my pois recovery. Oh right, wasn't it related to Cortisol?

[Warrior]

Hey man,
good to hear you are doing better than a year ago as you say.
Can I ask, since you are quite knowledgable on this, do you know about licorice?
I read about it somewhere that it is very important for overcoming pois and had brought it but I don't feel any difference after taking it. I'm wondering what that means as it relates to my pois recovery. Oh right, wasn't it related to Cortisol?

Nah I haven't personally tested licorice but have heard of it being medicinal, especially for leaky gut.

If it doesn't do anything for you, it's probably not worth taking. POIS is very complex and as we've seen time and time again, we all seems to respond to different treatments.

I'm not really that knowledgeable. All I've done is fortunately found things that have worked for me and I am eternally grateful for that. I still have lots of food sensitivities that make moving on from an animal-based or carnivorous diet unfavourable.

[Warrior]

So recently over the past few months, I began noticing some strange eye symptoms. Feelings of a tension in 1 eye at a time, which would oscillate between the eyes. Sometimes in the right. Sometimes in the left. Despite all of that, my vision remains very clear. It feels like a tension, or eye ache. Almost like the mussel in the eye won't completely relax. I began noticing this around the time period when I was exploring a lot of methylation nutrients, glycine, and many other stuff maybe 2-3 months ago. Initially I didn't think anything of it and actually thought it was a symptom from eating non AB foods. Well since then it's persisted quite decently, appearing on and off throughout the day.

I went to see an Optometrist today about my concern, who did a lot of comprehensive testing. After lots of discussion, explaining exactly what I was experiencing, and putting me through many of the different tests involving all sorts of equipment, etc the results came back that overall my eyes are very healthy. I am short-sided in my right eye (have been for as long as I can remember.) He thinks that perhaps the over compensation of 1 eye leads to the fatigue of another and vice versa. Overall he was not concerned about what I was experiencing and I'm over the moon about the results. I also told him about many of the supplements I've been experimenting with, the stress of my chronic condition, food sensitivities, my physical labour job etc.

But I will say this experience has kind of shaken me a bit. I want to be more careful about my health moving forward. I think I have been a bit reckless in regards to testing too many things in a short period of time, combined with my physically intensive job and tendancy to undereat on my diet.

I think testing as many things as we can is amazing, but we definitely need to be careful. I am grateful for the level of relief I've been able to experience on my AB diet and at this point I am much more of the mindset of acceptance rather than trying to fight my sensitivities. I want to take a much more natural, careful, and slow path moving forward.

For the record I have permanently improved my methylation and subsequently sensitivities, but it isn't perfect enough to expect to eat other foods and not get any symptoms. I still get a moderate amount of symptoms especially if I'm eating it day in day out. SAM-e has definitely replenished whatever deficiency I must've had, given that these days I no longer feel a deep need for taking a B complex, eggs, or SAM-e etc... I am at the moment giving myself a complete break from ALL supplements except for the occaisional magnesium, D3, and vitamin C.

If your POIS symptoms are still full-blown then you obviously have less to lose in terms of experimenting with a lot of things, but for me, I'm just going to work on accepting my situation more. I'm eternally grateful for all of the progress I have made, and I want to enjoy the level of health that I still have.

I think at this point my options are, that imo adhere to a more natural approach:

1) work on making animal-based diet better i.e, i recently bought a new BBQ which has made eating meat much more appetising. I still struggle with the constant influx of sugary and acidic fruit to meet baseline carbohydrate needs

2) potentially try carnivore for 3 months minimum - this would solve my constant battle of being hungry / under-eaten if it works for me

3) experient with some things that have a high safety profile, that have a high potential for improving my existing state of health, and are very natural i.e., i recently bought some authentic (sun-dried), activated, organic maca i plan on eventually playing with

4) I may try the immune stack again at some point in the future, but for now I intuitively feel like giving my body a big break from everything, and getting it back to a natural state as much as possible.

My current protocol is really just an animal-based diet, D3/k2, vitamin C, and some magnesium. I no longer appear to need the B complex, SAM-e, raw garlic, or fenugreek. This is a result from topping up my methylation. So clearly I think there must be a link to methylation -> raw garlic/fenugreek. I will still keep these supplements on my main page though for documentation. Who knows too, perhaps in the future I will need these again.

[Andre2505]

yes I already told you that I think I have excessive methylation because I took SAM-E for a few weeks and felt worse, I just wanted to know how to take them. A few days ago I tried the SAM-E again and felt worse. After a while I took 2.5g of glycine and niacin every 1/2 hour. It seems to have made me feel better a little

[Warrior]

yes I already told you that I think I have excessive methylation because I took SAM-E for a few weeks and felt worse, I just wanted to know how to take them. A few days ago I tried the SAM-E again and felt worse. After a while I took 2.5g of glycine and niacin every 1/2 hour. It seems to have made me feel better a little

If you still have over methylation symptoms after stopping SAM-e, then glycine and niacin can help. In that case something like a magnesium glycinate would also be beneficial right before bed-time if you wanted to stay on a daily dosage of glycine. Niacin is more used for utility, meaning temporarily reducing methyl groups, whereas glycine should in theory only buffer excess. Otherwise just take it as a sign your body not needing SAM-e.

[Warrior]

My response to https://www.reddit.com/r/POIS/comments/1ceae8f/same_safe_alternative/

Let me illustrate my personal annecdote re SAM-e:

For a long time, I was taking a 150 Forte B complex and regularly eating eggs (packed with choline). This was not enough to fix the severe methylation deficiency I had. It wasn't until I took SAM-e that it 'replenished' my methylation. Now I do not take any methylation supplements including SAM-e or B complex. Haven't touched them in a long time as many of my depleted methylation symptoms i.e., brainfog and very severe food sensitivity symptoms (I still have food sensitivities, but they improved since the SAM-e), have completely gone away. AFAIK most people take SAM-e only for a temporary period of time to fix the methylation deficiency. Once it's 'fixed', your body will actually tell you it won't need it by reacting unfavourably. I now also no longer need to take raw garlic or fenugreek. They don't do anything since I supplemented SAM-e for that temporary period of time.

AFAIK, SAM-e did not cause any harm on me (and I took it for quite a decent period of time), but I will never know for sure. Obviously there's a risk to it like you already stated.

Safer SAM-e alternatives might be creatine, TMG, L-methione, choline, etc. They certainly do not all work the same, but they may still fix or improve the methylation problem you are trying to fix through SAM-e. For me for example, choline was not sufficient in fixing whatever problem I had that SAM-e was successful in fixing. I also used to take creatine monohydrate many years ago and never noticed any impact on improving my POIS symptoms (which are impacted by methylation.)

[SchizoPIOS]

Hey man, quick update,

So I've been following a meat+root veg diet for a bit more than 10 days now, i eat mostly lamb or beef , with homemade potato fries, sometimes celeriac and some onions with the meat. Its been going well, I actually feel satiated now when im done eating, and I can definitely feel the hunger coming progressively instead of feeling completely bloated and the next moment you're starving.
I abstained for nearly 2 weeks, then thought it was time to release, and for the first time in years, I actually completely focused on myself when I M'd, I didn't watch porn, and just tried to relax as much as possible and was really calm, it felt good to release, didnt have much symptoms, the next day I actually felt a lot less tense around my pelvic area, so I decided to do it again last night, at some point i told myself maybe i shouldnt O but I didn't listen to myself and had a few symptoms this morning, the most significant was my hearing became worst. The past 2 weeks my hearing has become so fucking good, even my family noticed it, my mom made a few comments about how crisp my hearing is, but today I have to ask people to repeat themselves etc... So I think maybe I should only release like every couple days, not sure the exact number thats something i will have to figure out. My apetite was also a lot lower today after the 2nd O, but yesterday I did not notice any difference, I actually felt the bliss after you O if you know what I mean on the 1st night, but not as much on the 2nd, so tldr I should definitely let my body some time inbetween Os to recover, also I should M being completely mindfull especially since I suffer from PE so I can use that time to work on that, slow down, focus on the feeling and relax the body with deep breaths.

Besides that, I feel like the diet is helping out so much, not feeling completely tired after every meal and bloated and full but still hungry, Im also doing some short cold showers either in the afternoon if its too hot or in the mornings.
Thank you for coming up with your protocol man the animal based diet really does help out a lot of the underlying issues!

[Warrior]

Hey man, quick update,

So I've been following a meat+root veg diet for a bit more than 10 days now, i eat mostly lamb or beef , with homemade potato fries, sometimes celeriac and some onions with the meat. Its been going well, I actually feel satiated now when im done eating, and I can definitely feel the hunger coming progressively instead of feeling completely bloated and the next moment you're starving.
I abstained for nearly 2 weeks, then thought it was time to release, and for the first time in years, I actually completely focused on myself when I M'd, I didn't watch porn, and just tried to relax as much as possible and was really calm, it felt good to release, didnt have much symptoms, the next day I actually felt a lot less tense around my pelvic area, so I decided to do it again last night, at some point i told myself maybe i shouldnt O but I didn't listen to myself and had a few symptoms this morning, the most significant was my hearing became worst. The past 2 weeks my hearing has become so fucking good, even my family noticed it, my mom made a few comments about how crisp my hearing is, but today I have to ask people to repeat themselves etc... So I think maybe I should only release like every couple days, not sure the exact number thats something i will have to figure out. My apetite was also a lot lower today after the 2nd O, but yesterday I did not notice any difference, I actually felt the bliss after you O if you know what I mean on the 1st night, but not as much on the 2nd, so tldr I should definitely let my body some time inbetween Os to recover, also I should M being completely mindfull especially since I suffer from PE so I can use that time to work on that, slow down, focus on the feeling and relax the body with deep breaths.

Besides that, I feel like the diet is helping out so much, not feeling completely tired after every meal and bloated and full but still hungry, Im also doing some short cold showers either in the afternoon if its too hot or in the mornings.
Thank you for coming up with your protocol man the animal based diet really does help out a lot of the underlying issues!

Good to hear man. Do you think the AB diet has improved your actual POIS symptoms?

And yeah, find a frequency of ejaculation that works best for you. When my symptoms were at their absolute worst, I could afford to ejaculate maybe once a month without experiencing any symptoms. Now my ideal frequency is probably once every 2 weeks or so. I could release willy nillingly - and have in the past, but I wouldn't feel as optimal compared to when I consciously modulate it - even with my protocol.

Finding your ideal ejaculation frequency: https://www.taylorjohnson.life/how-often-should-you-ejaculate/. This guy teaches semen retention. I think many SR practices can be beneficial to POISers. But I like to combine the best of both worlds - attempt to improve your symptoms medically (learning from the POIS community and subreddit), while also learning to find what works best for you in regards to a SR lifestyle - ideal frequency of release, exploring non ejaculatory orgasms and sex, etc.

[SchizoPIOS]

Yeh I feel like it helps for sure, although I feel like I'm not eating enough atm, meat is quite expensive here especially the good cuts, and sometimes it can get quite boring so Im not fully restricting myself and if friends or family want to go eat out I don't fully restrict myself. eating more meat is always a good idea

I read the article you linked, its got solid advice, I feel like its always good to keep things balanced, thanks for sharing!

[Warrior]

For some odd reason, I respond amazingly to LifeExtension D3 brand far better than NOW D3 brand. I literally feel worst after taking NOW D3.

Feel better on this one:
7000iu D3 LifeExtension which contains the following ingredients including. D3 (cholecalciferol) 175mg, extra virgin olive oil, gelatin, medium chain triglycerides, glycerin, purified water, rosemary extract

Feel worst on this one:
10,000D3 NOW which contains the following ingredients including. D3 (cholecalciferol, specifically stating from Lanolin) 175mg, extra virgin olive oil, bovine gelatin, glycerin, water, safflower oil

Here's what Claude AI thought:

Lanolin sensitivity: The NOW brand specifically states that their D3 is derived from lanolin, which is a wax secreted by wool-bearing animals. Some people may have a sensitivity or allergy to lanolin, which could cause adverse reactions or discomfort. The LifeExtension brand does not specify the source of their D3, so it might be derived from a different source that your patient tolerates better.

Medium chain triglycerides (MCT): The LifeExtension brand contains MCT, which is absent in the NOW brand. MCT is a type of fat that is easily digestible and rapidly absorbed by the body. Some people find that MCT enhances the absorption and effectiveness of fat-soluble vitamins like vitamin D3. This could potentially contribute to your patient feeling better on the LifeExtension brand.

Rosemary extract: The LifeExtension brand includes rosemary extract, which has antioxidant and anti-inflammatory properties. Although the amount is likely small, it's possible that your patient may be experiencing some additional benefits from this ingredient.

Individual response: Every person's body is unique and can respond differently to various supplements or ingredients. It's possible that your patient simply tolerates the LifeExtension brand better due to their individual biochemistry and genetics.

---

I've literally been getting more depressed since taking the NOW brand (which I only begun as it was more accessible and cheaper than the LifeExtension). I will confirm this more through the coming weeks but so far it certainly seems to be significant at least for me. The typical symptom I experience when my D3 gets low (or at least when I stop the LifeExtension supplement for a prolonged period of time) is auditory thought noise.

Keep in mind too I've taken 21,000iu D3 from LifeExtension brand all in 1 day quite frequently. So it has nothing to do with the dosages.

Lesson here is don't fix what isn't broken, and if you ever change anything up brand-wise, don't assume the new brand works identical. Once you find something that works, just stick to it or be very careful changing things up.

[Warrior]

I think there is a significant link between LifeExtension D3 & my food sensitivities. My POIS and food sensitivities appear to dramatically improve when taking this D3 supplement by LifeExtension.

I'm going to investigate this further moving forward w/ blood testing to check D3 levels according to level of symptom and relief.

I've taken other D3 supplements and they do not appear to be as potent as this one. It contains other ingredients potentially having a medicinal benefit but I'm skeptical, apart from maybe they're making D3 more bioavailable for my system.

Maybe D3 mega-dosing via potent LifeExtension D3 supplement is what is behind the effectiveness.

Interesting links to explore:
https://www.reddit.com/r/covidlonghaulers/comments/omg5lt/has_anyone_else_tried_mega_dosing_vitamin_d3/

I think it may be possible that those with POIS or at least for myself, the optimal level of D3 will be higher than the threshold for reducing symptoms... I will explore this idea in the coming weeks... it just seems like even when my D3 level was very high, it only took a few weeks of zero supplementation for symptoms to begin intensifying, which may indicate that we need higher levels than normal for optimal relief...

"When you make D3 in your skin (from natural sunlight), it lasts 2-3x longer in your body then when taking it as a supplement"

This would explain why my D3 levels seem to drop more quickly after supplementing my levels compared to getting it naturally through sunlight.

[Warrior]

The D3 Experiments (Work in progress page)

Warning: It's highly recommended you work with a doctor when taking megadoses of D3 which can be dangerous and even deadly if done irresponsibly. With that being said, I believe megadosing D3, or at the very least getting your D3 levels to the higher level of safe range, has enormous potential for improving POIS symptoms. Read up on the following resources: How Not To Die With High Dose D3 Therapy, The Miraculous Results Of Extremely High Doses Of The Sunshine Hormone Vitamin D3, and The Coimbra Protocol. I am not a doctor. I am simply sharing information about a protocol which I believe has enormous potential for improving POIS symptoms.

I see two main D3 strategies I will test for addressing POIS symptoms:

1) Getting D3 serum levels (25-hydroxy) to the upper end of the conventional range = 40-50ng/mL. (Safest)

2) Megadosing D3 until level of symptom remission, where serum levels may need to rise well above conventional range (Dangerous if not done under medical supervision)

I think taking high dosages of D3 has enormous potential.

I’ve already seen a lot of its potential from the moderate amount I’ve been taking thus far.

I think it’s possible it could completely transform my food sensitivities beyond their current level.

German doc recommended for autoimmune patients 120ng/ml for transformative effects.

I took 21,000iu daily for a month or two and reached 100ng/ml, but stopped out of fear of toxicity levels.

Will do a full write up + comprehensive research into this as I think it has huge potential.

My D3 shot up to 98.6 ng/mL (16/02) after 2-3 months of 21,000iu per day. Then I stopped for a few weeks and re got tested on the 07/03, with a D3 level of 60.2 ng/mL. So from 16/02, to 07/03 (20 days apart), D3 25-hydroxy level fell from 98.6 ng/mL to 60.2 ng/mL.

Even when my levels were at 60.2 ng/mL, I still stopped taking any D3 thinking my levels were satisfactory. A few weeks later I was blindsighted by an increase of symptoms.

Recommended ranges of D3 is currently debated. From my research, minimal range imo for those with inflammatory disease is 70-80 ng/mL. Others may still benefit from higher dosages and serum levels. This article is an interesting read up for that.

Warning: Do your own independent research. I’m not a medical specialist or doctor by any means. None of this is medical advice.

http://perfecthealthdiet.com/2010/08/the-amazing-curative-powers-of-high-dose-vitamin-d-in-aging-and-autism/

The goal is to identify the most effective high vitamin D3 dosage and blood level long-term (thats still reasonably safe). There's a solid chance that those with POIS or any other inflammatory chronic disease will do better on higher dosages and blood levels of D3 than the norm.

In 2022 (16/08/22), I had my D3 tested as per request of my specialist. I didn't think at the time I would be deficient in D3 given that my work at the time required me to be out in the sun very frequently. The test result came back as 79 nmol/L or 22 ng/mL... I would personally conder this on the low end, though by generic medical standards it would be considered ok. The fact that my D3 was this low despite spending lots of time out in the sun at the time is probably quite telling... again may support the theory behind inflammatory diseases chewing through D3 at faster rates.

Many times in the past I have actually quoted here in my journal of either how reducing D3 (stopping its supplementation) has increased auditory thought (mental noise), worstened POIS symptoms, etc, and how increasing its dosage to higher amounts (at least 14,000iu) improved my POIS, food sensitivities, and overall health drastically.

The questions I need to answer once and for all:
- What is the optimal range of D3 for me?
- Does a high serum level and/or megadosing D3 have potential in curing my food sensitivities completely?
- Does vitamin D3, when dialled in at optimal range, fix all levels of social apathy/anhedonia? (In the past I noticed this appeared to go away completely around the time period I was doing a lot of experimentation with Nanna1s stack where I was taking high amounts of D3.)

https://www.coimbraprotocol.com/the-protocol-1
https://vitamindwiki.com/Is+50+ng+of+vitamin+D+too+high%2C+just+right%2C+or+not+enough#Overview_of_the_controversy
https://www.holisticcharlotte.com/dont-overlook-the-necessity-of-vitamin-d-cofactors/

[SchizoPIOS]

Hey bro, another update
I'm doing better, I've started a morning stretching routine, trying to stay consistent with my meals, although sometimes when I don't consume enough sugar I feel irritated. Overall I feel more connected with my body, I've noticed I feel calmer and more in tune with my body during the warmer months of the year, but at the same time my refractory period and POIS are worst during those months, all in all its a trade-off thats definitely beneficial because my diet tends to be cleaner and I start doing more healthy activities like stretching, spending time in nature and connecting with family, I live in the UK and the cold months can be brutal, my favorite season is spring where I feel the most in balance.

I've been feeling extremely horny today so I did peak at explicit content earlier, thankfully it was only images, I was experimenting with non-ejaculatory pleasure recently but today my horniness was consuming my thoughts too much, its been a week since my last O. I ended up masturbating, since Im circumcised I think I really need to get myself some lube haha because masturbating feels really unsatisfactory without it, I will get some before next time.

After a couple days of abstinence, it feels like my entire body is erect, if that makes any sense, right now after my O I already feel a lot more sluggish and softer.

So yeh, In summer I feel less sexual but that means I can focus on other things, I feel more human and less governed by my balls, I gaze way less at women on the streets whereas in winter even though my POIS symptoms and refractory period lessen it feels like its on my mind 24/7. I'd love to move somewhere with less harsh winters and longer warm months, ideally with more sunlight because in the UK we can go multiple days without sunlight.

I also think I need to increase the time between Os, first one I had abstained for 3 weeks and felt amazing after, felt the post nut bliss, but the last 2 times when its been 1 week inbetween I haven't. Or I could experiment more with non-ejaculatory pleasure but then I have PE so it can be difficult

[Warrior]

The D3 Experiments

German doc recommended for autoimmune patients 120ng/ml for transformative effects.

I took 21,000iu daily for a month or two and reached 100ng/ml, but stopped out of fear of toxicity levels.

Will do a full write up + comprehensive research into this as I think it has huge potential.

My D3 shot up to 98.6 ng/mL (16/02) after 2-3 months of 21,000iu per day. Then I stopped for a few weeks and re got tested on the 07/03, with a D3 level of 60.2 ng/mL. So from 16/02, to 07/03 (20 days apart), D3 25-hydroxy level fell from 98.6 ng/mL to 60.2 ng/mL.

"Man Dies of Hypercalcemia, a Condition Caused by Excessive Vitamin D Consumption"

"The naturopath had advised the man to take eight drops of vitamin D daily. Over a period of more than two years, the man consumed between 8,000 and 12,000 international units (IU) of vitamin D daily.

The recommended daily amount for the average person is between 400 and 1,000 IU.

Due to the high amount of vitamin D the man was taking, he had an excessive amount of calcium in his blood, which led to kidney damage.

?It was surprising to see the degree of kidney function he had lost suddenly almost to the point of requiring dialysis,? Dr. Bourne Auguste, a clinical fellow in home dialysis at Toronto General Hospital and the University of Toronto, told Healthline."

Contact a neurologist!

Thanks for pointing out the dangers of high dose D3 supplementation.

One way of reducing the calcification risk associated with high dose D3 is to take vitamin K2 alongside D3. It forces the extra absorbed calcium into the bones. I have personally been taking 170mcg of K2 per 10,000iu, sometimes even more.

Some recommend 1mg of k2 for every 10,000iu of D3 to be safe. Most recommend at least 100mcg of K2 per 10,000iu.

There are additional safety measures one would want to do when exploring high dose D3 therapies. Comprehensive blood work, etc. This is why it's important you seek professional guidance.

Those recommended daily amounts for D3 are laughable and outdated. No one around here will benefit from such small dosages. Read the Coimbra Protocol.

Of course those reading this need to consult with their doctor, but make sure you find one that is actually open-minded and up to date with the latest D3 information.

Edit: I have added the following warning segment thanks to your concerns:

Warning: It's highly recommended you work with a doctor when taking megadoses of D3 which can be dangerous and even deadly if done irresponsibly. With that being said, I believe megadosing D3, or at the very least getting your D3 levels to the higher level of safe range, has enormous potential for improving POIS symptoms. Read up on the following resources: How Not To Die With High Dose D3 Therapy, The Miraculous Results Of Extremely High Doses Of The Sunshine Hormone Vitamin D3, and The Coimbra Protocol. I am not a doctor. I am simply sharing information about a protocol which I believe has enormous potential for improving POIS symptoms.

[Warrior]

Hey bro, another update
I'm doing better, I've started a morning stretching routine, trying to stay consistent with my meals, although sometimes when I don't consume enough sugar I feel irritated. Overall I feel more connected with my body, I've noticed I feel calmer and more in tune with my body during the warmer months of the year, but at the same time my refractory period and POIS are worst during those months, all in all its a trade-off thats definitely beneficial because my diet tends to be cleaner and I start doing more healthy activities like stretching, spending time in nature and connecting with family, I live in the UK and the cold months can be brutal, my favorite season is spring where I feel the most in balance.

I've been feeling extremely horny today so I did peak at explicit content earlier, thankfully it was only images, I was experimenting with non-ejaculatory pleasure recently but today my horniness was consuming my thoughts too much, its been a week since my last O. I ended up masturbating, since Im circumcised I think I really need to get myself some lube haha because masturbating feels really unsatisfactory without it, I will get some before next time.

After a couple days of abstinence, it feels like my entire body is erect, if that makes any sense, right now after my O I already feel a lot more sluggish and softer.

So yeh, In summer I feel less sexual but that means I can focus on other things, I feel more human and less governed by my balls, I gaze way less at women on the streets whereas in winter even though my POIS symptoms and refractory period lessen it feels like its on my mind 24/7. I'd love to move somewhere with less harsh winters and longer warm months, ideally with more sunlight because in the UK we can go multiple days without sunlight.

I also think I need to increase the time between Os, first one I had abstained for 3 weeks and felt amazing after, felt the post nut bliss, but the last 2 times when its been 1 week inbetween I haven't. Or I could experiment more with non-ejaculatory pleasure but then I have PE so it can be difficult

Good to hear things are improving for you mate.

For a UK folk, I would especially suggest for you to dial in D3 given that you get less sun exposure compared to other places around the globe.

[Warrior]

Here's an excellent link on the differences of opinion and controversy surrounding ideal D3 supplementation levels: https://vitamindwiki.com/Is+50+ng+of+vitamin+D+too+high%2C+just+right%2C+or+not+enough#Overview_of_the_controversy

So according to this page, a 25-hydroxy D3 lvl of 50ng/mL is optimal for infections and Covid-19. I think there is a very decent probability an infection of some sorts is behind POIS, and similar pathology to long covid.

Would be really interesting if more of us could get D3 25-hydroxy done and evaluate at what level POIS symptom improve (if they do) according to D3 level. Though this may be quite tedious and time consuming to do.

Fortunately 50ng/mL is still within the conventional range (only some experts would still believe its too high), though it is on the high end upper limit. Any higher and you are moving into territory you generally must take more care with.

Though I have a sense for me personally, I will do better on higher dosages. I will be exploring this over the coming month.

[Andre2505]

Here's an excellent link on the differences of opinion and controversy surrounding ideal D3 supplementation levels: https://vitamindwiki.com/Is+50+ng+of+vitamin+D+too+high%2C+just+right%2C+or+not+enough#Overview_of_the_controversy

So according to this page, a 25-hydroxy D3 lvl of 50ng/mL is optimal for infections and Covid-19. I think there is a very decent probability an infection of some sorts is behind POIS, and similar pathology to long covid.

Would be really interesting if more of us could get D3 25-hydroxy done and evaluate at what level POIS symptom improve (if they do) according to D3 level. Though this may be quite tedious and time consuming to do.

Fortunately 50ng/mL is still within the conventional range (only some experts would still believe its too high), though it is on the high end upper limit. Any higher and you are moving into territory you generally must take more care with.

Though I have a sense for me personally, I will do better on higher dosages. I will be exploring this over the coming month.

I collected the tests today and I have 80 ng/ml of vitamin D, now I don't know whether to stop for a moment because I probably have even more because I continued to take it even after I did the tests. But yes, I would like to keep myself among the 80 and 100. One thing that worries me a little is that I have 115 mcg/dl of vitamin A, so I'm in excess. The maximum should be 80. I also have a slight excess of zinc. And I tested positive for VCA-igG and EBNA IgG of the Epstein bar virus (EBV) but I am negative for VCA-igM. So I probably had the virus in the past and I probably had mononucleosis. I tested negative for Cytomegalovirus (CMV).

[Warrior]

A therapy or medical treatment is the attempted remediation of a health problem, usually following a medical diagnosis.

Medical diagnosis is the process of determining which disease or condition explains a person's symptoms and signs. It is most often referred to as a diagnosis with the medical context being implicit. The information required for a diagnosis is typically collected from a history and physical examination of the person seeking medical care. Often, one or more diagnostic procedures, such as medical tests, are also done during the process.

I’ve already added medical disclaimers to my posts. People here can make their own decisions weighing up the risks… pls do not spam my thread.

[Warrior]

Yesterday I took 3-4x 200mg of SAM-e, spread out in 30 min stints or so, and definitely feel like it’s helping again, which would indicate that my SAM-e lvls do still get depleted over time even tho I’m occasionally taking B complex, eggs for choline, etc…

I’m currently exploring the possibility that high serum lvls of D3 + completely replenished SAM-e lvls = potential complete remission of food sensitivities

I haven’t taken any SAM-e for a few months… I stopped taking it as every time I went to try, even weeks spread between dosages, I always felt like my body didn’t need it. So all of this is evidence that, at least for me, and most likely others, SAM-e gets depleted from POIS over time….no amount of B complex, choline (eggs) or red meat seems to satisfactory replenish it, but equally, it’s probably best to view it like a nutrient. Once topped up - and you will probably know once it gives you side-effects ie makes you feel worst rather than better, you can take a break for a while until the levels are depleted again….

I also have no doubt that increasing my D3 serum lvls have improved my POIS symptoms enormously…. I don’t know the exact serum lvls, all I know is that I experience a very distinct improvement in symptoms when I up my supplement dosage, which is obviously increasing my serum lvls to a specific range…