Author Topic: Rush desensitization  (Read 2605 times)

Vandemolen

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Rush desensitization
« on: April 09, 2011, 07:32:07 AM »
A Dutch hospital will do a test with injections in the lymph nodes. Only 3 injections are needed againt hay fever. 25 people will have 3 injections with pollen against hay fever. And 25 people will get a fake injection. I can't get this injections because it's only for people who only have hay fever. Beside POIS I have a dust allergy, parfum allergy, tobacco smoke allergy... The Dutch research is a response to a Swiss research 3 years ago.
POIS since 2000. Very bad since 2008. I knew that I have POIS since June 2010. Desensitization since March 2011. I stopped with desens in July 2016. I have 50% less POIS. And only 1 day of POIS. Purified CBD works for me, but I am allergic for CBD.

b_jim

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Re: Rush desensitization
« Reply #1 on: April 11, 2011, 01:08:39 AM »
I'm not sure to undertand. The fact to inject the antigen (pollen.... or sperm?) directly in the Lymph nodes is much more effective than in blood ?

That would be very very interesting !
Taurine = Anti-Pois
Suffering from lyme disease

Vandemolen

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Re: Rush desensitization
« Reply #2 on: April 11, 2011, 03:49:10 PM »
Yes it is. In the Lymph nodes you only need 3 injections. In the blood 52.
POIS since 2000. Very bad since 2008. I knew that I have POIS since June 2010. Desensitization since March 2011. I stopped with desens in July 2016. I have 50% less POIS. And only 1 day of POIS. Purified CBD works for me, but I am allergic for CBD.

Habibou

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Re: Rush desensitization
« Reply #3 on: April 12, 2011, 09:25:46 AM »
Yes, it is a serious track , I try to contact seekers and hospitals which are willing to give it a trial  :

Background: IgE-mediated allergy can be treated by subcutaneous allergen-specific immunotherapy (SIT). However, the percentage of allergic patients undergoing SIT is low, mainly due to the long duration of the therapy and the risk of severe systemic allergic reactions associated with the allergen administration. To improve the safety and attractiveness of SIT for patients, alternative routes of allergen administration are being explored, such as sub-lingual or oral administration. Methods: The present study evaluated direct intralymphatic allergen administration as a means to enhance SIT with bee venom and cat fur allergens in mice. Allergen-specific antibody and T-cell responses were analysed by ELISA and flow cytometry. The therapeutic potential of intralymphatic immunisation in sensitised mice was analysed using an anaphylaxis model. Results: Direct injection of the major bee venom allergen phospholipase A2 or the major cat fur allergen Fel d 1 into inguinal lymph nodes enhanced allergen-specific IgG and T-cell responses when compared with subcutaneous injections. Moreover, only intralymphatic immunisation stimulated the production of the Th1-dependent subclass IgG2a, which is associated with improved protection against allergen-induced anaphylaxis. Biodistribution studies showed that injection into the lymph node delivered antigen more efficiently to subcutaneous lymph nodes than subcutaneous injection. Conclusions: As intralymphatic immunisation induced more than 10-fold higher IgG2a responses with 100-fold lower allergen doses than subcutaneous immunisation, this approach should allow to reduce both the number of allergen injections as well as the allergen dose, improving both efficacy and safety of SIT.



This seems safter, according to me! It is an article FOR this procedure to recover from allergy, with less injections, and less allergen to inject, to be continued...
« Last Edit: April 12, 2011, 09:28:23 AM by Habibou »
Brain fog 90%  + tired all the time ,sport intolerance, fast heartbeat, colon inflammation