Have you tried taking a B complex? I've had amazing success with B complex in general. Fixed up a lot of mood, mental issues and seemed to improve my POIS solution very significantly. I've also heard the B vitamins are better taken as a B complex so you don't become deficient in one by taking a big dose of another.
You could take the B complex along with the B3 and matcha if the B complex does not have 500mg of B3 nicotinamide.
Just a suggestion / something to try, as you're seeing lots of success with B3, and a B complex did wonders for me 
Just realised too that you are on a gluten-free diet! Our solutions are very similar. Have you tried fenugreek & garlic?
Hi warrioronthetrot.
Appreciate your reply and insights. My comments:
- My B3 + matcha pre-pack method is still working for me (roughly 2 years now).
- Yet to try B-complex, fenugreek & garlic. I'm interested in testing this for when I didn't properly follow my pre-pack method:
- For example, pre-pack <1 hour before O.
- In that situation I get mild POIS lasting a few days.
- 33% chance of nasal cold sore so I combat with Vitamin C and Lysine supplements immediately.
- If cold sore symptoms do start (tingling nose/lips) then I take valaciclovir immediately (single dose of 3 tablets).
Do let me know how you use B-complex, fenugreek & garlic. When, how often, what format, etc.
Thanks again.