August 23 2023: POST-ORGASMIC ILLNESS SYNDROME SUCCESSFULLY TREATED WITH OMALIZUMAB (T J)
Use a youtube downloader to download and watch the video.
NSAIDs, high dose antihistamine therapy and SSRIs were considered ineffective.
Treatment: 3 months of therapy with 300 mg Omalizumab every 4 weeks. Patient had improvement of symptoms 3 days after start of therapy. I will add this to the pois paper treatment thread.
https://en.wikipedia.org/wiki/Omalizumab#Mechanism_of_action
Very interesting case report !
Sadly, they do not share how they came to decide to try omalizumab ( Xolair) for POIS. It is an allergic asthma treatment, and also treats urticaria (hives). The patient's symptoms were nausea and a decline of cognitive functions, starting 5 minutes after O, and his blood tests were normal, so I wonder how the immunology department came to this decision.
Xolair works essentially by depleting free IgE antigens. so that basophils, mast cells, and dendritic cells are gradually down-regulated. This case report goes in line with the last article of the late Dr. Waldinger, that POIS is an auto-immune disorder.
Has anyone been able to get hold of the article from the youtube video using omalizumab ( Xolair) for POIS ?
I wish I could test this medication seems promising but expensive.
Used by injections. The standard price for one of these injections costs more that 200euros or even close to about 250euros. Medical healthcare pays most of it back here in my country for those suffering from severe asthma. But if you have POIS then you must pay the full amount! Part of our problem is that we still don't have a proper diagnoses for POIS.
A Proper diagnoses would be such an advantage and this alone does not seem fair. Many people get help with their illnesses from government, but if you have POIS everything is cut down and often left in the dark with administration. My doctor recognises that I have POIS but can not organise me all the benefits that I'd normally be entitled to get because of these administrative issues with POIS!
