POIS Theory Master List

[Muon]

https://www.reddit.com/r/POIS/comments/1ezk7lg/pois_starting_after_30/

Interested in hearing from guys who have “secondary” POIS that started in your 30s or 40s. What are your theories as to what triggered it? What changed if anything?

I did not have POIS in any shape or form for the majority of my life and then seemingly spontaneously about 7 years ago in my late 30s a switch flipped and nothing was ever the same. I thought I was dying at first lol.

I do have a theory that my lifestyle in my 30s triggered the condition, particularly my enthusiastic use of a certain powdery white substance. I think I caused some sort of brain chemistry imbalance that set off a chain reaction. A few one offs aside, the lifestyle is well behind me, but I have not healed. It would be great if the injury was not permanent, but who knows.

https://www.reddit.com/r/POIS/comments/1ezk7lg/comment/ljl7k0o/

In my case, however, I think it is somehow genetics. My family has a history mental disorders. Depression, anxiety, psychosis etc.

[Muon]

Do we need fMRI studies for POIS, like these?
https://www.mdpi.com/1648-9144/60/8/1370
https://www.mdpi.com/2076-3425/14/5/450

[demografx]

Do we need fMRI studies for POIS, like these?
https://www.mdpi.com/1648-9144/60/8/1370
https://www.mdpi.com/2076-3425/14/5/450

Sure, Muon, got $50,000+++?


The cost of an fMRI study - - NOT including professional administrators, science writers, lab workers, medical analysts, etc. - - can vary significantly depending on the location and institution. At the University of Michigan, the scan rate is $561 per hour, with a recommendation to budget $600 per hour for grant proposals. Yale School of Medicine charges $696 per hour for their Siemens 3T scanners, with a typical 1.5-hour session costing $1,044. Prices can also differ by state, with costs ranging from $274 in Arkansas to $343 in California.