Someone online suggested these two ideas to lower catecholamines and up regulate MAO-A
1. Avoid foods high in PEA phenylethylamine (basically all protein) and use PEA and tyrosine free protein powder (tyrex1)
2.
https://pubs.acs.org/doi/10.1021/acschemneuro.0c00628This suggests that downregulating Sirt1 results in upregulated MAO-A (which is what you want). Slow release NAM (nicotinamide) in doses of 1-2g should do that for you.
Additionally I suggest NAC slow release 1200mg to balance glutamate and reduce catecholamines
I tried no 2 and it did reduce my reactions to showers significantly, I had never tried this form of niacin before, I only had tried the nicotinic acid flush version for POIS which didn't work years ago, I also tried a non flush version but this wasn't nicotinamide. I did have two cetirizine on the morning of the shower which may have contributed.
I didn't have the NAC sustain slow release version so I need to buy this and test out as NAC only has a half life of five hours, I did wake up hungover one morning maybe because I only used the normal version the night before with NAM but then I took two NACS in the morning and it went.
It seems I feel the effects of NAC way more than usual when I stack with the NAM so they work well together. On the 3rd time I tried this stack I got a really bad headache and nausea, I took 2.4g of NAC with 1500mg NAM in a short time so I probably took too much.
I then cut down my animal protein and eggs consumption down drastically and this is where I see massive changes. It's like the asperger symptoms I have vanish, Music sounded good again, motivation came back, compulsive checking of phone stopped, speech and social skills became normal, no anixety and my confidence became god like I could speak to any stranger naturally without any autism showing. The NAM and NAC could also have contributed.
It felt my brain and neurotransmitters were working as they should be for the first time in as long as I can remember. I lost my a lot muscles in the last few days but it was worth it for the discovery. This fixes my dysautonomia symptoms and excess neurotransmitter issue. I would rather feel better and functioning instead of not feeling good but having an in shape built up body.
A few days without the animal protein or eggs intense fatigue did start to set in but my head still felt clearer than ever before, I will still eat animal protein (high PEA foods) but just in much lower amounts.
On low fodmap my POIS became worse than before , now on this low animal protein diet my POIS worsened even further - wet dreams are causing me bad symptoms again when most of last year they stopped giving me symptoms, possibly it could also be to do with poor food choices on this low protein diet, I was eating fodmaps, histamine etc.
