I was prescribed Cipralex for OCD. I now believe my (mild) OCD is connected to POIS as it correlates in strength with some of the other symptoms. Cipralex did literally nothing for my OCD, but also didn't make me worse in any noticeable way.
Please note that different anti-depressants can have very very different effects on your body! This was just my experience with Cipralex in particular.
Personally I get a mini-depression when I have a bad POIS episode. I've had clinical depression before and it feels exactly like that, but only lasts a week or so. Seems pointless and potentially dangerous to experiment with anti-depressants for something that (in my case at least) clearly isn't a normal case of depression IMHO.