Author Topic: TRT Success Story  (Read 478 times)

quotz

  • Newbie
  • *
  • Posts: 26
Re: TRT Success Story
« Reply #15 on: February 22, 2021, 02:39:27 PM »
She had it forever yeah, shes prone to depression, the females from her mom side of the family all diagnosed with clinical depression. I suppose POS has to do a lot with depression.

Does she suffer from some kind of female premature orgasm? And when did you notice your POIS, after dating her?

I had POIS before dating her. She does not suffer from female premature orgasm.

Could there be some microbes in POISers that could get transferred to other people through close contact like through sexual intercourse and then they could maybe activate MCAS or SIBO or molecular mimicry of the autoimmunity process thus giving POIS to somebody as well?

Yeah I dont think so. After orgasming its quite normal to feel a bit sad, but in the POIS case its more extreme than usual. After orgasm prolactin gets released, which is a dopamine antagonist, which basically makes us unable to focus and feel like crap. B6 is a dopamine agonist and a prolactine suppresant, and it does the job of treating POIS after orgasming for me. If somebody mails me cabergoline or other alternatives I will happily experiment for you.


She had it forever yeah, shes prone to depression, the females from her mom side of the family all diagnosed with clinical depression. I suppose POS has to do a lot with depression.

Higher SHBG means u wont have free test, but with low SHBG I am injecting a lot of T because its all getting used up super quickly. When I had higher SHBG I was feeling way better than now. I think the golden number is around 40-50 for SHBG, which I had a year ago pre-coffee.

Also 475ng/dl is not great at all. Get yourself a few nice doctors to put you on TRT, but most importantly educate yourself with the subreddit so you dont rely too much on the doctors as they dont know much anyway. Your life will change 180 degrees, if there was Testosterone stocks I will invest in it with all my savings
Do you know though what could be the root cause of not high enough Testosterone production? I have read a lot about how hormones production occurs like the Pregnenolone conversion with the usage of Thyroid hormones by the body and how Pregnenolone is made from the Cholesterol and how all nutrition must be good so that there are resources for the full steroidogenesis to occur and how good sleep ensures the LH is able to be generated so that then it can activate the Leydig cells for them to convert the Pregnenolone into Testosterone using the Thyroid hormones and how other anti-androgenic factors and hormones like Cortisol, Estrogens, Prolactin and etc. can decrease both the production of Testosterone through impairment of GnRH/LH/FSH/'steroidogenesis and by directly lowering it but if one does not have optimal hormones then that means there is something else wrong with their body because if one has enough nutrition, base hormone production factors, proper enzyme and body system functioning then why would they have any hormonal issues?

A full blood test of LH, FSH, Prolactin, Cortisol, Estrogen, VitaminD, Total Testosterone, SHBG, Albumin, all immune and inflammatory factors and markers, all of the Thyroid markers and hormones could show me a full picture of the state of my body and health and also explain if there are any other imbalances that might not be letting my body to fully optimally properly produce the hormones.

Go on mayoclinic and search for Hypogonadism causes. Theres 2 types, primary (your testicles not producing enough T), and secondary (your brain/pituitary gland not producing enough hormones that tell the testicles to produce T). As of now, they dont know exactly why the secondary cause exists, but primary can be caused from injuries or even mumps when you were a kid, but generally its quite of a black hole thing and nobody knows why. Docs check for Vit D and if its low you will get supplements to see if your T will go up, Cortisol also suppresses T but you could easily do a 24hr Cortisol urine test, or even the normal blood test, and check that out. If you go to a mens health clinic they will test all these things you mentioned and have a rough idea of whats going wrong, but its still just scratching the surface, and if ur T is low then you will get TRT anyway, theres no other fix.

resilient

  • Newbie
  • *
  • Posts: 1
Re: TRT Success Story
« Reply #16 on: February 22, 2021, 04:01:51 PM »
Hi mate. Congrats on your treatment success.

I have a couple of questions.

Would you say you experienced progressive improvement in your symptoms as your Total T levels kept going up with your therapy?

Also you said earlier that Total T of 600 ng/ml was too low.

So at what Total T levels would you say you started feeling pretty significant improvement in your pois symptoms? Thanks.

Journey

  • Sr. Member
  • ****
  • Posts: 433
  • INTP, 19 y.o. aware of POIS since 2019
Re: TRT Success Story
« Reply #17 on: February 22, 2021, 04:31:29 PM »
She had it forever yeah, shes prone to depression, the females from her mom side of the family all diagnosed with clinical depression. I suppose POS has to do a lot with depression.

Does she suffer from some kind of female premature orgasm? And when did you notice your POIS, after dating her?

I had POIS before dating her. She does not suffer from female premature orgasm.

Could there be some microbes in POISers that could get transferred to other people through close contact like through sexual intercourse and then they could maybe activate MCAS or SIBO or molecular mimicry of the autoimmunity process thus giving POIS to somebody as well?

Yeah I dont think so. After orgasming its quite normal to feel a bit sad, but in the POIS case its more extreme than usual. After orgasm prolactin gets released, which is a dopamine antagonist, which basically makes us unable to focus and feel like crap. B6 is a dopamine agonist and a prolactine suppresant, and it does the job of treating POIS after orgasming for me. If somebody mails me cabergoline or other alternatives I will happily experiment for you.


She had it forever yeah, shes prone to depression, the females from her mom side of the family all diagnosed with clinical depression. I suppose POS has to do a lot with depression.

Higher SHBG means u wont have free test, but with low SHBG I am injecting a lot of T because its all getting used up super quickly. When I had higher SHBG I was feeling way better than now. I think the golden number is around 40-50 for SHBG, which I had a year ago pre-coffee.

Also 475ng/dl is not great at all. Get yourself a few nice doctors to put you on TRT, but most importantly educate yourself with the subreddit so you dont rely too much on the doctors as they dont know much anyway. Your life will change 180 degrees, if there was Testosterone stocks I will invest in it with all my savings
Do you know though what could be the root cause of not high enough Testosterone production? I have read a lot about how hormones production occurs like the Pregnenolone conversion with the usage of Thyroid hormones by the body and how Pregnenolone is made from the Cholesterol and how all nutrition must be good so that there are resources for the full steroidogenesis to occur and how good sleep ensures the LH is able to be generated so that then it can activate the Leydig cells for them to convert the Pregnenolone into Testosterone using the Thyroid hormones and how other anti-androgenic factors and hormones like Cortisol, Estrogens, Prolactin and etc. can decrease both the production of Testosterone through impairment of GnRH/LH/FSH/'steroidogenesis and by directly lowering it but if one does not have optimal hormones then that means there is something else wrong with their body because if one has enough nutrition, base hormone production factors, proper enzyme and body system functioning then why would they have any hormonal issues?

A full blood test of LH, FSH, Prolactin, Cortisol, Estrogen, VitaminD, Total Testosterone, SHBG, Albumin, all immune and inflammatory factors and markers, all of the Thyroid markers and hormones could show me a full picture of the state of my body and health and also explain if there are any other imbalances that might not be letting my body to fully optimally properly produce the hormones.

Go on mayoclinic and search for Hypogonadism causes. Theres 2 types, primary (your testicles not producing enough T), and secondary (your brain/pituitary gland not producing enough hormones that tell the testicles to produce T). As of now, they dont know exactly why the secondary cause exists, but primary can be caused from injuries or even mumps when you were a kid, but generally its quite of a black hole thing and nobody knows why. Docs check for Vit D and if its low you will get supplements to see if your T will go up, Cortisol also suppresses T but you could easily do a 24hr Cortisol urine test, or even the normal blood test, and check that out. If you go to a mens health clinic they will test all these things you mentioned and have a rough idea of whats going wrong, but its still just scratching the surface, and if ur T is low then you will get TRT anyway, theres no other fix.
How do mumps suppress the Testosterone production?

BoneBroth

  • Sr. Member
  • ****
  • Posts: 279
Re: TRT Success Story
« Reply #18 on: February 23, 2021, 09:45:55 AM »
Yeah, testosterone deficiency might be what is biochemically causing the POIS symptoms, and adding testosterone might block the symptoms. However the underlying cause is still there causing other health issues in the long run, and when you stop using testosteone the symptoms will come back, probably even worse. I believe the underlying cause  are related to gut problems - fix the gut, eat for the good gut bacteria and fix the stress that causes the gut issues. Then the body might correct testosterine deficiencies by itself.

quotz

  • Newbie
  • *
  • Posts: 26
Re: TRT Success Story
« Reply #19 on: February 26, 2021, 01:00:55 PM »
Hi mate. Congrats on your treatment success.

I have a couple of questions.

Would you say you experienced progressive improvement in your symptoms as your Total T levels kept going up with your therapy?

Also you said earlier that Total T of 600 ng/ml was too low.

So at what Total T levels would you say you started feeling pretty significant improvement in your pois symptoms? Thanks.

Men should have a total T of 1200 ng/dl if not even more, theres research stating men used to have higher levels back in the days 50-80 years ago google it, with SHBG being 40-60, and albumin being in the correct levels too. Yes TRT totally fixed everything. Either get a good doc, or do self-therapy, dont risk it by going to bs docs, save some $$ and get urself an amazing doc its worth it if u dont have the time to read the reddit stuff.


Yeah, testosterone deficiency might be what is biochemically causing the POIS symptoms, and adding testosterone might block the symptoms. However the underlying cause is still there causing other health issues in the long run, and when you stop using testosteone the symptoms will come back, probably even worse. I believe the underlying cause  are related to gut problems - fix the gut, eat for the good gut bacteria and fix the stress that causes the gut issues. Then the body might correct testosterine deficiencies by itself.

Your way of thinking is dangerous and its bro-science. If you go to Mayo Clinic or Cleveland Clinic they wont say "fix your gut" or whatever. If you want good gut bacteria go do a fecal transplant of someone that has normal T levels and check if your levels will improve, quite of a simple experiment actually. You wont find a doctor that will diagnose you with "gut problems" for hypogonadism, ever, so youre gonna have to make a fecal transplant yourself, which you can easily find resources online about it but theres some risks involved so research well and choose a great poop donor. Eating good food is of course very important, but its pseudoscience for saying it will treat hypogonadism. Good food is preventative medicine, not treatment in most cases. Please stop spreading fake news. Hypogonadism is a chronic condition btw, I will have to be on TRT forever, if I stop TRT of course I will get the symptoms back. Also, TRT doesnt treat symptoms, it treats the cause, being not enough T. Treating symptoms would be like taking Acetaminophen for a headache, when the headaches are caused by a condition such as hypothyroid or whatever. Please do your research and dont post these things, or if you do make sure its either backed by research or youve experimented yourself

BoneBroth

  • Sr. Member
  • ****
  • Posts: 279
Re: TRT Success Story
« Reply #20 on: February 26, 2021, 01:38:18 PM »
We just have diffrent experiences quotz. I have over 25 years of knowledge about what you think is "psuedoscience" and I know that it is neither "psuedoscience", nor "dangerous". I see people cure themself from a varity of long term degenerative diseases by not listening to their doctor and choosing the alternative way instead. We just have diffrent experience. If I would be you I would at least find a SIBO-therapist just to hear what he has to say and if he have similar cases.
« Last Edit: February 27, 2021, 04:32:23 AM by BoneBroth »

Iwillbeatthis

  • Sr. Member
  • ****
  • Posts: 389
Re: TRT Success Story
« Reply #21 on: February 26, 2021, 04:41:01 PM »
Yeah I'm with Bone Broth on this one. Lots of things can influence testosterone production like lifestyle factors : sitting all day, bad sleep, little exercise, watching porn, high cortisol, refined carbs, low HDL, under eating/eating for connivence. Then gut imbalances can also halt testosterone production, once I started a high count  custom probiotic suddenly my libido increased a lot started to get morning erections again. Did you know testosterone production starts with cholesterol?

I saw a guy rose his testosterone naturally from 11nmol to 28nmol he was doing the things I listed above before and now this is what he's doing:
Strong daily routine and respecting your body
Getting 10k steps a day
Having meaningful relationships
Eating Healthy fat
Respecting sleep
Lifting heavy

When he was on 11nmol he was also taking testosterone booster pills with no success. I'm glad the TRT works for you though.

It's also not psuedoscience just conventional medicine doesn't really look into detail about what the root cause of health problems are most of the time, it's more about checking your levels of basic things and managing the symptoms you have with drugs. Conventional medicine is disease management (with the exceptions of Infections and Cancer) rather than focusing on reversing disease like with functional medicine.


« Last Edit: February 26, 2021, 04:50:33 PM by Iwillbeatthis »

BoneBroth

  • Sr. Member
  • ****
  • Posts: 279
Re: TRT Success Story
« Reply #22 on: February 27, 2021, 03:45:03 AM »
Thanks Iwillbeatthis! As I said I'm I not at all against hormonal support (not replacement), I write articles about it! A matter of fact I think everyone over 40 should take some extra hormones to increase their life quality as hormones drop at that age. Only yesterday I read that experts say we could become 250 years old if we only supplement with three important hormones as we age: growth hormone, melatonin and DHEA. I would add testosterone as well. But the establishment doesnt want you to become so healthy and old so they make sure the knowledge is hidden and supply is soooo difficult to get and soooo expensive and impossible in all ways, though it is the year of 2021 and we are almost sending a car to planet Mars every year...

So hormones are yet expensive, and att your age, quotz, 99,99% of all people should be able to have adequate or hight testosterone levels, unless there is some very unusual permanent damage or rare disease. There are many causes of temporarily decreasing testosterone levels (lifestyle, activities, foods, supplements) that can be fixed, some just in a matter of days (people are for example reporting immidiate improvement of POIS on hollidays, when they relax, swim, beeing in the sun and get distance from stressful people and situations, I experienced that too). I've made a list of theese things, and things that increase testosterone here. You should also be aware of that the cause of your low testosterone might not only cause low testosterone, but a multitude of deficiencies that in the long term might cause much worse complications and shortened life span. So if you take testosterone replacement only, and not fixing the cause, its just like turning off your cars warning signal and contiuing driving when the oil is almost gone. Not a good idea.

Since you are so "allergic" to what you call "pseudoscience" you should see Christoffer Walkers Youtube channel about increasing testosterone naturally. Walker make sure that what he sais is backed up with science. "pseudoscience" is just a another word with origin from the same establishment that the doctors that havn't helped you. Along with their pharmaceutical drugs, words like that are just ment to toxify your brain and indotrinate you to think that you, and others, are not capable of finding the sollutions of their own problems without the control of "public experts" and "officials" - a mental jail and the main reason behind all the problems the world experiences.

I also recommend watching this comprehensive and science based lecture about hormones and health by hormonal expert Dr Thierry Hertoghe.

I just got an idea - may sitting with your legs crossed long time decreas testosterone production? Please do my man-spread-poll here!
« Last Edit: February 27, 2021, 05:12:49 AM by BoneBroth »

Going less Crazy

  • Sr. Member
  • ****
  • Posts: 439
Re: TRT Success Story
« Reply #23 on: February 27, 2021, 11:23:42 AM »
250 years old is a bit of a stretch there don't ya think
My POIS managed with modified Paleo Diet (@ diet that 100% manages my pois)Believe my POIS stems from inflammation in the gut. O and stimulation = neuro POIS from inflammation from the gut

Current supplements: 1 tsp olive oil in the morning. 400mg-600mg Ibuprofen for mood/insomnia if needed.

BoneBroth

  • Sr. Member
  • ****
  • Posts: 279
Re: TRT Success Story
« Reply #24 on: February 28, 2021, 04:44:50 AM »
Its not me who thinks it, its a well known naturopathic doctor called Peter Whilhelmsson who has made books about aging and hormones and theres science to back it up. Rats extend their life times with equal long life when giving specific hormones in their water supply. Anyway, 150 or 250 years old isnt important, the point is that many important hormones fall to near zero percent as we age and with extra supplement there can be extended life and lifequality. Thats confirmed from other hormonal researchers as well, for example dr thierri hertoghe, chief of hormonal society with some 7000 doctors.
« Last Edit: February 28, 2021, 04:53:15 AM by BoneBroth »

Iwillbeatthis

  • Sr. Member
  • ****
  • Posts: 389
Re: TRT Success Story
« Reply #25 on: February 28, 2021, 06:33:35 AM »
The one thing about growth hormone is that it increases IGF-1 which then activates the MTOR pathway and too much or too little MTOR is heavily linked with cancer. This doesn't stop Joe Rogan from taking it though lol. I would love to take these hormones as I'm sure I would feel great on them however I'm not sure if it's worth the risk.

Muon

  • Hero Member
  • *****
  • Posts: 2104
    • MCAD Thread
Re: TRT Success Story
« Reply #26 on: February 28, 2021, 04:10:49 PM »
The one thing about growth hormone is that it increases IGF-1 which then activates the MTOR pathway and too much or too little MTOR is heavily linked with cancer. This doesn't stop Joe Rogan from taking it though lol. I would love to take these hormones as I'm sure I would feel great on them however I'm not sure if it's worth the risk.

Ironfeather has acne and many of her family members passed away due to cancer (mTOR involvement?). POISers do react to high carb diets and/or milk: https://poiscenter.com/forums/index.php?topic=2695.msg35257#msg35257
Some mTOR related pathway might be overactive. It plays a role in cellular stress responses regarding release of ER stress proteins. Something for research to investigate I guess.

quotz

  • Newbie
  • *
  • Posts: 26
Re: TRT Success Story
« Reply #27 on: February 28, 2021, 08:03:12 PM »
My opinion was so strong on this one because for the 2-3 years I was trying to diagnose my hypogonadism, where no doctor knew what the f is going on and they wanted to diagnose me with mental health issues, I tried all the "natural" ways there are. I say natural in quotation marks because I dont agree with the current definition of what natural means but lets just go with the "natural" definition that you would assume it would mean. But basically I tried all there is, supplements, diets, working out, sun, literally anything I could get my hands on, anything anyone ever mentioned online. I have secondary hypogonadism, which means my balls are working fine, but my pituitary gland is not sending signals to my balls to make more T, so its not a permanent injury to the balls. Who knows what could be the reason, check out this article titled "Youre not the man your father was" on Forbes https://www.forbes.com/sites/neilhowe/2017/10/02/youre-not-the-man-your-father-was/?sh=7ffba0718b7f. Literally the West is doomed as all industrialized societies have declining T levels generation-wise. Its a combination of plastics, pollution, industrial waste, less physical activity, too much sitting, crap food, and many more but its difficult to pin down only one.

I am just saying I wasted 2-3 yrs of my life doing the natural way rather than going straight for TRT. I am a reborn man since I started. No man should ever have hypogonadism, it should be illegal and the western countries should make this a top priority to save men from declining T