Author Topic: My experience with POIS  (Read 808 times)

findacure

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My experience with POIS
« on: January 25, 2021, 01:06:50 PM »
Hi all,


Hope you're all doing ok.

Since I started PMO'ing from a very early age, over time I've found that after ejaculation, within 20 minutes, I feel like my brain is inflamed and just doesn't work as efficiently. I get slurred speech and just want to lie in bed.

It's literally ruined my life, and there have been times when, because I PMO'd earlier that day, I missed out on various social events.

It's a nightmare because it's made me a really boring person; I have to plan everything in advance.

It's like after O'ing, the life gets sucked out of me.

The symptoms seem at their worst when I get semen leakage. For example, I was talking to a girl at work and she turned me on, and I leaked semen (precum) and I could feel my brain starting to shut down, it's horrible.

And how do I explain it to others? It's such an awkward and embarrassing illness.

Over the years I've tried Diclofenac (a strong NSAID), which provided mild relief.

I also tried Niacin, which didn't help.

I tried Testogel testosterone patches, which worked wonders, but they can lead to infertility and testicular cancer.

More recently I've been trying B12 and D3 which helps a little, but some days my brain just feels burnt out, and this is consistently when I've O'd earlier in the day.

Fortunately, if I O and then go to sleep, by the morning I'm back to normal; it's just that sometimes I want to be spontaneous and do something unplanned in the morning. I shouldn't have to bow down to this illness.

I will never give up, but I feel that this illness is holding me back from realising my true potential and I feel like my life is on hold until then.

Recently I went to see an endocrinologist who really listened to me and my situation. He's been brilliant so far.

I had a blood test last year and found the following, while I was taking Testogel:

Testosterone was 17.2 with an LH of 3.7, FSH 3.6.

Sex hormone binding globulin was29.3 and the reference range is 14 - 94, so he was concerned that this is low.

Cortisol at 533. The free T4 is 17.7, TSH 2.5. (I have high cortisol, this illness doesn't help with all the stress it causes me).

So what I'm doing at the minute is waiting for 6 weeks (since I stopped taking the Testogel) and have booked in for blood tests of the following:

O in the morning before:
Week 1: LH, FSH, oestradiol, testosterone, prolactin, vitamin D, vitamin B12, folic acid, ESR, CRP and ferritin.

Then begin diet (see below)
No O before:
Week 2: LH, FSH, oestradiol and testosterone.

No O before:
Week 3: LH, FSH, oestradiol and testosterone.

One hypothesis we came up with was that EVERYONE who O's has a drop in testosterone and other such chemicals, but it's my body's response to this. However part of me does feel that it's an allergic reaction because I rarely sneeze, but do sneeze a little bit after O'ing.

In terms of diet, I've always eaten a high carb, high sugar diet so that isn't likely to help, so the endocrinologist has recommended I try a diet of:

No:
Potato, Bread, Pasta, Water Melon, Pineapple, Grapes, Dates, Mangos, Banana - to see if this improves my symptoms.

Another theory is that my prolactin levels rise after O'ing, so perhaps I could trial medication that reduces prolactin.

I will report back once I have my blood test results in the next couple of weeks. Any thoughts greatly appreciated.

berlin1984

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Re: My experience with POIS
« Reply #1 on: January 25, 2021, 03:14:55 PM »
Thanks for posting!

However part of me does feel that it's an allergic reaction because I rarely sneeze, but do sneeze a little bit after O'ing.

Note: Histamine is involved in allergies, but is also something released on orgasm (for us at least). So it does not necessarily mean that what you/we have is an allergy.

No:
Potato, Bread, Pasta, Water Melon, Pineapple, Grapes, Dates, Mangos, Banana - to see if this improves my symptoms.

Did your doctor explain why he picked each item? Some of those items sound like a low histamine diet. (or low biogenic amines diet)

Another theory is that my prolactin levels rise after O'ing, so perhaps I could trial medication that reduces prolactin.

Let me know in that thread if you trial Vitex agnus-castus.

In general, you can also try everything that counters prolactin rise, e.g. rise dopamine instead (people on the forum have success with Tyrosine, but there is more things...)

drop247

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Re: My experience with POIS
« Reply #2 on: January 25, 2021, 05:44:18 PM »
Do you have a source for Testosterone causing testicular cancer? Thanks

findacure

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Re: My experience with POIS
« Reply #3 on: January 26, 2021, 03:35:50 AM »
Thanks for posting!

However part of me does feel that it's an allergic reaction because I rarely sneeze, but do sneeze a little bit after O'ing.

Note: Histamine is involved in allergies, but is also something released on orgasm (for us at least). So it does not necessarily mean that what you/we have is an allergy.

No:
Potato, Bread, Pasta, Water Melon, Pineapple, Grapes, Dates, Mangos, Banana - to see if this improves my symptoms.

Did your doctor explain why he picked each item? Some of those items sound like a low histamine diet. (or low biogenic amines diet)

Another theory is that my prolactin levels rise after O'ing, so perhaps I could trial medication that reduces prolactin.

Let me know in that thread if you trial Vitex agnus-castus.

In general, you can also try everything that counters prolactin rise, e.g. rise dopamine instead (people on the forum have success with Tyrosine, but there is more things...)

Thank you. The doctor didn't explain why, I think it was to switch off 3 things but can't remember what they were called.

Maybe everyone has a histamine response to O'ing, but my body/brain overreacts? I'm hoping that adjusting my diet can minimise this overreaction.

But I don't want to have to avoid those foods altogether, I want to get to the root cause of the problem.

After these tests I will try Acetyl L-Tyrosine (tyrosine alone is pretty useless, Acetyl is a carrier that, like a Trojan Horse, can help trick the blood brain barrier and get more of the tyrosine through).

I will try Vitex agnus-castus, do you know what dose you recommend and when to take it? Presumably 1 tablet once daily? What were your experiences like with it?

findacure

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Re: My experience with POIS
« Reply #4 on: January 26, 2021, 03:38:33 AM »
Do you have a source for Testosterone causing testicular cancer? Thanks

Hi there, my endocronologist says it stops your body from naturally producing testosterone, especially if production is normal like mine.

https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/testosterone-therapy/art-20045728

Not testicular sorry it this risk: "Stimulating noncancerous growth of the prostate (benign prostatic hyperplasia) and growth of existing prostate cancer." (see above link)

Iwillbeatthis

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Re: My experience with POIS
« Reply #5 on: January 26, 2021, 06:40:23 AM »
Do you have a source for Testosterone causing testicular cancer? Thanks

Hi there, my endocronologist says it stops your body from naturally producing testosterone, especially if production is normal like mine.

https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/testosterone-therapy/art-20045728

Not testicular sorry it this risk: "Stimulating noncancerous growth of the prostate (benign prostatic hyperplasia) and growth of existing prostate cancer." (see above link)

I saw in some study it said that the group of men with high free testosterone levels had a lot more prostate cancer occurring than the groups with less.

And yes thats the problem with TRT once you start you will have to be on it for the rest of your life. Human growth hormone also increases cancer risk as it increases MTOR which is heavily linked to cancer.

However a lot of people say the benefits from feeling good from these hormones outweigh the risks for them.

demografx

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« Last Edit: January 26, 2021, 02:21:15 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

drop247

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Re: My experience with POIS
« Reply #7 on: January 26, 2021, 02:36:01 PM »
Thanks demografx. From your links I see that Testosterone therapy doesn't directly cause prostate cancer either.

demografx

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Re: My experience with POIS
« Reply #8 on: January 26, 2021, 02:46:07 PM »
Thanks demografx. From your links I see that Testosterone therapy doesn't directly cause prostate cancer either.
Interestingly, it also states, “In fact, new research suggests that this treatment [TRT] may actually reduce the risk of aggressive prostate cancer.”
« Last Edit: January 26, 2021, 03:15:20 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business