Key experience on my POIS - important for nanna1 and POIS scientists

[swell]

My guess is that:
a) behaviorally: we are overly-sensitive to stimuli (at least I am).  We are prone to somatic illnesses - where somatic is real (and not something imaginary).  Our brains and neural circuits get hard wired on our childhood experiences.  In my case, I was scared of worms, spiders; and growing up I simply thought these ejaculation organs were something scary (at first that it is a worm/spider).  I failed to understand it being normal physiology till I entered college.
b) medically: I think our Methionine-Homocysteine cycle is at root.  (This cycle is what synthesizes SamE, Neurotransmitters, clearing homocysteine, manufacturing glutathione, methylation of dna, production of enzymes.  I think this cycle (whatever its called has systemic ramifications affecting immune function.   

What exactly happens that causes POIS and how we got it while many others never had it?

[swell]

I am gluten and dairy free since I changed my diet.  This bring an important deficiency, my diet is indeed low in calcium, and calcium supplements I dont feel good taking them.   I am flexible naturally, have no bone problems, but when I take Citracal (i.e. Calcium Citrate/Carbonate), I feel I loose flexibility.  Maybe there is a better form of Calcium? 
// Point of Contention:  I am taking supplemental Vitamin D3 (good quantity, upto 2000IU) with K (50% of RDA).  This concerns me, since Vit D mobilizes calcium in blood and if I am low in Calcium then could I be setting myself up for trouble in that Vit D will put it out from my bones?

Ashwaghanda I do take it sometimes, though not regularly.  In me, it affects positively my mood, though no change in body temperature. 

About the Thyroid as an organ (its a metabolic gatekeeper that interferes with certain Rx drugs).  And the Naturally dissected Thyroid, actually it is a wonderful compound.  I do believe hypo-thyroid is severely under-diagnosed by the 'system'. But that said, caution is necessary and I recommend docs approval to others, even though I did not go through it.

Note: while in my posts, I may appear to be critical of docs as if they dont answer questions.  But I actually do not blame docs per say.  In US, where I live, Insurance companies are very powerful and they "regulate" docs behavior and their practices.  In US, docs are very hesitant in ordering lab tests.  They face difficulties in getting re-imbursed and get dinged for making certain exceptions.  The "system" makes them perform their job per rigid defined practice and consequently, we patients dont get our questions answered and importantly dont get preventative medicine through lab tests.  I dont know if others feel all this, but I feel all this, every person being "constrained".  Failures happening because of the "system". 

[quikot]

PS: I also often had the 'feeling cold' issue, but for me the fix was Ashwagandha.

A lot of health websites and blogs recommend Ashwagandha for the Epstein Barr Virus and for liver health.. I must try this some day.

[swell]

For researchers that are looking at blood markers, my results are in, the measurements permitted by insurance.  I argued about Thyroid (let me have Free T3 at least) and Lipid measurements (particle size, particle count etc) importance of those numbers and without them it not being a complete picture, but sadly couldn't succeed.

TSH: 1.94 UIU/mL, T4: 1.24  ng/dL
Cholesterol: 194 mg/dL, Triglycerides: 38 mg/dL, LDL-C: 100 mg/dL, HDL-C: 87 mg/dL
Hba1c: 5.4% (i.e. 108mg/dL average glucose), Vit D: 32 ng/mL, ESR: 5  mm/hr
Total Iron binding capacity: 372 ug/dL
Iron saturation: 21%
Ferritin: 77 ng/mL
Iron: 77 ug/dL
Transferrin: 278 mg/dL
WBC: 5.3 K/UL
RBC: 5.32 M/UL
Hemoglobin: 14.4 gm/dL
Hematocrit: 43.5%
MCV: 82 fl, MCH: 27 pg, MCHC: 33 gm/dL
RDW: 14 %
Platelet count: 247 K/UL
MPV: 10.6  (report does not indicate units, though says: normal range= 6.5 to 12)
PMN%: 62.7
Lymphocyte%: 28.3
Monocyte%: 7.8
Eosinophil%: .8
Basophil%: .4
PMN Absolute: 3.3 (Polymorphonuclear leukocytes) K/uL
Lymphocyte Absolute: 1.49 K/uL
Monocyte Absolute: .41 K/uL
Eosinophil Absolute: .04 K/uL
Basophil Absolute: .02 K/ul
Uric acid: 5 mg/dL

Additions:
Antibody test results are all 0.2 where less than '1 Al' is Negative.  I dont understand at moment, what these antibody tests are saying.
Are all negative for: (Chromatin DNP, Ribosomal, SS-A IGG, SS-A AB, SS-B IGG, SS-B IGG, SMRNP, SMRNP AB, SCL 70 IGG, SCL 70 AB, J01 IGG, JO1 IGG AB, Centromere B AB, SM IGG, SM IGG AB, RNP IGG, RNP AB, DNA AB, DNA Antibody double-stranded, Ribosomal  P, Centromere B, ANA)

IMP: Wondering if someone can evaluate/critique my personal conclusions.  (Fyi: blood was drawn hours after daily 2-3 o's, though keep in mind I'm a recovered pois'er.  I stopped all supplements 24-48 prior).
1.  I seem to have a low inflammation state (Ref: WBC, ESR).
2.  Hemoglobin in my Red blood cells is low borderline (Ref: MCH, MCHC).  This concerns me since I take a daily iron supplement at my own advice/peril.
3.  So we know from wikepedia that Hemoglobin contains Iron + NO + Sulfur Proteins.  But my Iron levels seem normal.  Does that mean, NO or Thiol/Sulfur proteins could be low?  I need to figure this stuff out, why I cant survive without Iron.
4.   Overall immune system is towards suppressed but still normal (Ref: various immune components, WBC, etc)
5.   I have Innate dominance (Neutrophils, Macrophages, Dendritic cells are dominating the scene, while ironically Mast cells have been sidelined , totally un-expected or maybe the supplements which I occasionally take have been controlling the Mast cells?  Or maybe I'm nuts to be simplifying all this (basophil -> mast cell etc, but I am thinking it should be fair to do it.
6.    My adaptive  immune components, humoral-cellular is normal though on lower side.
7.    Neutrophil / Lymphocyte differential is normal.
8.    Not diabetic, but I have either Insulin Resistance or lack of Insulin, or I dont know what.  The anomaly is, I am normal weight, very low visceral fat.  (h1abc = 5.4 i.e. 108 glucose average).  I started measuring my glucose recently. My fasting glucose is around 115, max 120 I measured so far.  That is high.  My post-meal glucose has a significantly delayed peak (its like everything works slow in me).  Max I have measured has been 145.  // If you all know your glucose vitals and feel comfortable please share.  I think, my aberrant glucose could be a consequence of chronic high cortisol for prolonged periods, rather than traditional variables (insulin).  Since I'm skinny, so I dont think my insulin can be high.  And I know I have this constant fear of doom happening.
9.   Triglycerides / HDL is atypically low, keeping in view LDL is normal-high.  (I wish I could find particle size and count which would tell if this LDL is harmless or beneficial).
10.  Vit D is ok, though normal-low

[drop247]

I believe Ashwagandha increases thyroid hormones which helps a great deal with cold body feeling. For me it works acutely ti warm me up. Too bad it also seems to irritate my intestine. Otherwise it's a great drug for me.

[swell]

Wondering if someone can evaluate/critique my personal conclusions.  (Fyi: blood was drawn hours after daily 2-3 o's, though keep in mind I'm a recovered pois'er).
1.  I seem to have a low inflammation state (Ref: WBC, ESR)
2.  Hemoglobin in my Red blood cells is low borderline normal (Ref: MCH, MCHC)
3.  So we know from wikepedia that Hemoglobin contains Iron + NO + Sulfur Proteins.  But my Iron levels seem normal.  Does that mean, NO or Thiol/Sulfur proteins could be low?
4.   Overall immune system is towards suppressed but still normal (Ref: various immune components, WBC, etc)
5.   I have Innate dominance (Neutrophils, Macrophages, Dendritic cells are dominating the scene, while ironically Mast cells have been sidelined , totally un-expected or maybe the supplements which I occasionally take have been controlling the Mast cells?  Or maybe I'm nuts to be simplifying all this (basophil -> mast cell etc, but I am thinking it should be fair to do it.
6.    My adaptive  immune components, humoral-cellular is normal though on lower side.
7.    Neutrophil / Lymphocyte differential is normal.
8.    Not diabetic, but I have either Insulin Resistance or lack of Insulin, or I dont know what.  The anomaly is, I am normal weight, very low visceral fat.  (h1abc = 5.4 i.e. 108 glucose average).  I started measuring my glucose recently. My fasting glucose is around 115, max 120 I measured so far.  That is high.  My post-meal glucose has a significantly delayed peak (its like everything works slow in me).  Max I have measured has been 145.  // If you all know your glucose vitals and feel comfortable please share.  I think, my abberant glucose could be a consequence of high cortisol for prolonged periods, rather than other variables.
9.   Triglycerides / HDL is atypically low, keeping in view LDL is normal-high.  (I wish I could find particle size and count).
10.  Vit D is ok, though normal-low

Additions:
Antibody test results are all 0.2 where less than 1 is Negative.
Are all negative for: (Chromatin DNP, Ribosomal, SS-A IGG, SS-A AB, SS-B IGG, SS-B IGG, SMRNP, SMRNP AB, SCL 70 IGG, SCL 70 AB, J01 IGG, JO1 IGG AB, Centromere B AB, SM IGG, SM IGG AB, RNP IGG, RNP AB, DNA AB, DNA Antibody double-stranded, Ribosomal  P, Centromere B, ANA)

TSH: 1.94, T4: 1.24
Cholesterol: 194, Triglycerides: 38, LDL-C: 100, HDL-C: 87 
Hba1c: 5.4, Vit D: 32, ESR: 5
Total Iron binding capacity: 372
Iron saturation: 21
Ferritin: 77
Iron: 77
Transferrin: 278
WBC: 5.3
RBC: 5.32
Hemoglobin: 14.4
Hematocrit: 43.5
MCV: 82, MCH: 27, MCHC: 33
RDW: 14
Platelet count: 247
MPV: 10.6
PMN Absolute: 3.3 (Polymorphonuclear leukocytes)
Lymphocyte Absolute: 1.49
Monocyte Absolute: .41
Eosinophil Absolute: .04
Basophil Absolute: .02
Uric acid: 5

[Muon]

Which of these flavonoids had the best effect on your health?

[swell]

Apologies I have been absent.  I use Quercetin, Luteolin, Milk Thistle.  I open the capsules and mix it well in fatty food or Olive oil.  I could be wrong but if I have to rank today:  I would put:
Luteolin, Quercetin, Milk Thistle, but I use them all at same time : )

Which of these flavonoids had the best effect on your health?