Author Topic: My background and latest finding (POIS symptoms completely gone at this point!)  (Read 614 times)

eccentricbipois

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Hi eccentricbipois,
I have added you as reference members in the POIS Types Chart, at https://poiscenter.com/forums/index.php?topic=2338.msg19448#msg19448 .  You are listed in the type # 8, "POIS Type responding to antihistamines".
I have specified that you use 25mg of hydroxyzine, 30 mins to 1 hour before orgasm, at bedtime.

Thanks! There may be some changes and additions as I'm still very new to taking hydroxyzine (have only done this for about 2 months or so but have multiple successes). As I'm learning now, 25mg used to be enough for the first few times but unfortunately it feels like it's not quite enough to take care of the symptoms entirely anymore :( . I've tried taking 50mg hydroxyzine pamoate and while it does remove the symptoms completely again, my new problem is fighting off the sedation and drowsiness that lingers all day on that dosage, on top of the 12+ hours of sleep needed! (I don't get that nearly as much with 25mg).

After talking to an allergy specialist they suggested trying Cetirizine HCl since it has a similar pharmacology to hydroxyzine (didn't confirm the accuracy of this). Upon experience with cetirizine while it does help alleviate the POIS symptoms as well it introduces some side effects that make things worse for me (mostly all-day headaches, shortness of breath). They gave me samples of Levocetirizine Dihydrochloride (Xyzal) as well which I will try instead next time.

I'll certainly update if I find a good 2nd generation antihistamine to compliment the hydroxyzine pamoate to completely rid of the POIS symptoms and am open to recommendations. While a lot of progress has been made, there's still just a little more ways to go...

Best idea so far (reduces symptoms by ~70%): NSAID (Meloxicam, Ibuprofen), and ginger root supplements (~1g) an hour before orgasm to help with aching body and irritability. Also take frequent 10 minute breathing exercise to stimulate vagus nerve.
Armodafinil 100mg daily to help with brain fog.

eccentricbipois

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I tried Atarax (Hydroxyzine) about 10 years ago, but I didn't notice any relief for my POIS symptoms. As Nas says, it works well if you want to get to sleep.

Antrax is Hydroxyzine Hydrochloride which I never tried since I'm taking Hydroxyzine Pamoate (Vistaril), FWIW
Best idea so far (reduces symptoms by ~70%): NSAID (Meloxicam, Ibuprofen), and ginger root supplements (~1g) an hour before orgasm to help with aching body and irritability. Also take frequent 10 minute breathing exercise to stimulate vagus nerve.
Armodafinil 100mg daily to help with brain fog.

eccentricbipois

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An update: I've been trying different OTC antihistamines and have found loratadine to be the most helpful. I took 10mg loratadine along with 25mg of the hydroxyzine pamoate an hour before orgasm and I'm back to having the symptoms completely gone again. I realize this is preliminary so will follow up in a couple months time to see how this regimen works out long term.

EDIT: I realize the difference this time with loratadine and other antihistamines is that they work better if taken some time before O, rather than after.
« Last Edit: August 02, 2020, 06:23:44 PM by eccentricbipois »
Best idea so far (reduces symptoms by ~70%): NSAID (Meloxicam, Ibuprofen), and ginger root supplements (~1g) an hour before orgasm to help with aching body and irritability. Also take frequent 10 minute breathing exercise to stimulate vagus nerve.
Armodafinil 100mg daily to help with brain fog.