Pepto Bismol removed symptoms completely

[hurray]

John21, great to see you again!

(Everyone, John21 was the first POISer to ever post on a POIS internet group.

In 2007).

John21 was the first, I think you were the 6th Demo 

https://www.thenakedscientists.com/forum/index.php?topic=6576.0

[demografx]

POIS History Lesson!

John21, great to see you again!

(Everyone, John21 was the first POISer to ever post on a POIS internet group.

In 2007).

John21 was the first, I think you were the 6th Demo 

https://www.thenakedscientists.com/forum/index.php?topic=6576.0

...and b_jim posted right before me!

February, 2007!

hurray, when did you join??

[berlin1984]

Trying to link this with the CFS theories.

https://cfsremission.com/2017/04/03/pepto-bismol-bismuth-as-a-possible-antibiotic-for-cfsfmibs/
"There appears to be significant evidence that it may reduce some symptoms of CFS/FM/IBS in a subset of patients and thus should be discussed with you medical professional. The duration of many studies appear to be approximately 4 weeks."


https://forums.phoenixrising.me/threads/if-h2s-is-the-cause-is-bismuth-subsalicylate-the-treatment.263/

[hurray]

POIS History Lesson!

John21, great to see you again!

(Everyone, John21 was the first POISer to ever post on a POIS internet group.

In 2007).

John21 was the first, I think you were the 6th Demo 

https://www.thenakedscientists.com/forum/index.php?topic=6576.0

hurray,
...and b_jim posted right before me!

February, 2007!

hurray, when did you join??

I didn't find the forum until September 2008 

[demografx]

I didn't find the forum until September 2008 

hurray,

That still puts you in the First Class Supreme Section of the POIS...

https://tinyurl.com/yyhdxy97

[hurray]

Thanks Demo! 13 years later, we're still here 

[demografx]

Thanks Demo! 13 years later, we're still here 

hurray, absolutely amazing. You, me and others have kept this place alive - - AGAINST ALL ODDS!! Some of it has been rough sledding, but only a very few of us seem to appreciate that. And sometimes it’s really hard to endure some of the negativity!

But bottom line is we ARE moving forward. More fortunately than 90%+ of all rare disorders. And I would put our POIS Research Team at the top of that list of items-to-be-grateful-for.

[hurray]

Thanks Demo! 13 years later, we're still here 

hurray, absolutely amazing. You, me and others have kept this place alive - - AGAINST ALL ODDS!! Some of it has been rough sledding, but only a very few of us seem to appreciate that. And sometimes it’s really hard to endure some of the negativity!

But bottom line is we ARE moving forward. More fortunately than 90%+ of all rare disorders. And I would put our POIS Research Team at the top of that list of items-to-be-grateful-for.

Yes, we are definitely making progress  The current work of the POIS Research Team is very exciting - I can't wait to see what conclusions they come to.

Many people have made great contributions to this forum, and kept things going during harder times. Your positivity more than cancels out any negativity 

[demografx]

Yes, we are definitely making progress  The current work of the POIS Research Team is very exciting - I can't wait to see what conclusions they come to.

Many people have made great contributions to this forum, and kept things going during harder times. Your positivity more than cancels out any negativity 

MANY, many thanks, hurray!! It’s your sentiments - - and similar ones from other Forum Members - - that have kept me going here all these years!!

[nebraska]

on this forum there was a post from a person who found h2s sibo.  and he was completely feeling healthy on a sulfur-free diet (which is very similar to a histamine-free diet).
So, a low sulfur diet greatly helps the intestines with h2s sibo, but the most basic thing that is also prescribed is pepto bismol(and it helps).  You can stick with it for a week and tell the result for the sake of experiment.  That guy, by the way, had no sibo symptoms other than flatulence.

[Mr Raba]

Tried PB yesterday. Just 15 mL of liquid form in AM then another dose one hour or more before O about midnight last night.  Did not experience the onset at all last night and went to sleep. This AM feeling strong, maybe a minor tired effect. Mind in peace. I do not yet if I will try a dose today on day 1 or not. Trying to see how long yesterday’s doses work for.

[Mr Raba]

Trying to link this with the CFS theories.

https://cfsremission.com/2017/04/03/pepto-bismol-bismuth-as-a-possible-antibiotic-for-cfsfmibs/
"There appears to be significant evidence that it may reduce some symptoms of CFS/FM/IBS in a subset of patients and thus should be discussed with you medical professional. The duration of many studies appear to be approximately 4 weeks."


https://forums.phoenixrising.me/threads/if-h2s-is-the-cause-is-bismuth-subsalicylate-the-treatment.263/

Hi,

A key connection below: hydrogen Sulfide could then be an issue in both POIS and CFS. Thus providing further clues on why Pepto Bismol helps both.

From your second link:
“1. Try using Bismuth subsalicylate (BSS). This is commonly known as Pepto Bismol. Each tablespoon or chewable tablet contains 262 mg, and it aggressively soaks up hydrogen sulfide and pulls it out of your body (by turning the hydrogen sulfide into bismuth sulfide). At the same time, it has antibacterial activity that may kill off both the unfriendly bacteria and the biofilms they live in. One to two tablets 3 to 4 times a day will be enough (adjust the dose so that the gas is not too stinky). Give it a 3 to 4 week trial and see if it helps. Then post your results on our community bulletin board and let us know if it helps you.”

From healthrising.com:

“Naviaux’s paper has clearly sparked a lot of interest. Certainly, antecedents hovered in the background; metabolism has actually been a niche topic in ME/CFS for years. Lemle proposed that a hydrogen sulfide induced state of hibernation or hypometabolism caused the low energy problems in chronic fatigue syndrome in 2011. The Aussies have been doing metabolomics research for quite some time. Their 2014 review paper argued it could be helpful in ME/CFS.”

[drop247]

I read somewhere that if Pepto Bismol gives you dark stools it means you have a lot of hydrogen sulfide in your gut. Is this pseudo-science or does it have any basis in fact? It gives me dark stool but I thought it did that to everyone.

[John21]

I read somewhere that if Pepto Bismol gives you dark stools it means you have a lot of hydrogen sulfide in your gut. Is this pseudo-science or does it have any basis in fact? It gives me dark stool but I thought it did that to everyone.

I think that is a normal side effect.

[berlin1984]

A key connection below: hydrogen Sulfide could then be an issue in both POIS and CFS. Thus providing further clues on why Pepto Bismol helps both.
...

"Each tablespoon or chewable tablet contains 262 mg, and it aggressively soaks up hydrogen sulfide and pulls it out of your body (by turning the hydrogen sulfide into bismuth sulfide). At the same time, it has antibacterial activity that may kill off both the unfriendly bacteria and the biofilms they live in."

Thank you for bringing this up.

I googled a bit more and found those two blog posts interesting:
https://phoenixrising.me/research-2/hydrogen-sulfide-a-breakthrough-in-mecfs/h2s-a-big-breakthrough-for-chronic-fatigue-syndrome
https://phoenixrising.me/research-2/hydrogen-sulfide-a-breakthrough-in-mecfs/hydrogen-sulfide-and-chronic-fatigue-syndrome-the-originator-speaks
Too bad those blog posts don't have date/time values.

Maybe the orgasm opens some paths in the body that let h2s float around too much and lead then to a 1-7 days CFS like state.
Also as people said, correlated with the intensity of the orgasms (vessels pumping stronger).

We'd need a way to link this all with the other theories floating around. (e.g. virus theories, (auto)immune, blood volume/density, ...)
Or maybe we don't need to given there might be different kinds of POIS.

At least it would explain why diet changes can help so much (because they influence the gut microbiome and gut virome.)

[drop247]

I took 2 chewable Pepto Bismol tablets before bed and woke up with a black tongue lol. I'm not sure if it's due to Hydrogen Sulfide in my mouth or from reflux. I haven't tried it before orgasm yet.

[berlin1984]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273628/
"However, some recent evidence indicates that H2S released in the colon may also contribute to the control of arterial blood pressure."

https://pubmed.ncbi.nlm.nih.gov/30461448/
"H2S maintains the integrity of the mucus layer when derived from endogenous metabolism but is detrimental for this parameter when produced in excess by gut microbes. In inflammatory bowel diseases, an upregulation of H2S production from cysteine by the gut microbiota is observed concomitantly with a downregulation of enzymes implicated in its mucosal detoxification."

https://labblog.uofmhealth.org/lab-report/how-colon-prioritizes-gas-detox-over-energy-use
"How the Colon Prioritizes Gas Detox Over Energy Use"
I'm not a scientist, but does this mean that q10 is used up preferably for removing h2s, so there is less left for creating energy for the body?
(q10 deficiency common in cfs? https://me-pedia.org/wiki/Coenzyme_Q10 )

[Muon]

I took 2 chewable Pepto Bismol tablets before bed and woke up with a black tongue lol. I'm not sure if it's due to Hydrogen Sulfide in my mouth or from reflux. I haven't tried it before orgasm yet.

Oral dysbiosis? Dead bacteria? I had this once when flushing my mouth with a H2O2 solution. Also my fungal nail turned black and died off when I applied Vicks Vaporub to it for the first time. Some strain may die off shifting dysbiosis.

Oh before I forget, Is it possible to eat Vicks Vaporub? Perhaps someone knows this. Is it toxic? If so in what quantity? There are some strong anti-fungal and anti-bacterial compounds in there.

The active ingredients in Vicks VapoRub are camphor (a cough suppressant and topical analgesic), eucalyptus oil (a cough suppressant) and menthol (a cough suppressant and topical analgesic). The inactive ingredients in Vicks VapoRub include cedarleaf oil, nutmeg oil, petrolatum, thymol and turpentine oil. https://vicks.com/en-us/safety-and-faqs/faqs/vicks-vaporub-faq

[drop247]

I think it's just sulfur in my saliva reacting with the bismuth to create bismuth sulfide, which is black.

[CharlesB]

I read somewhere that if Pepto Bismol gives you dark stools it means you have a lot of hydrogen sulfide in your gut. Is this pseudo-science or does it have any basis in fact? It gives me dark stool but I thought it did that to everyone.

I think that is a normal side effect.

Agreed, my understanding is that black tongue/stools is a very common side effect (I have both when taking it.)

http://scienceline.ucsb.edu/getkey.php?key=2243