Immunophenotypical Characterization of a Brazilian POIS Patient (15 oct 2019)

[Muon]

For general POIS understanding, I think that this is an important fact that in your case injections of diluted semen in the blood caused you symptoms.

These are SC injections. It doesn't reach the peripheral vascular system it goes straight to the lymphatic system.

[Muon]

The Chinese man from the Chinese paper also has a history of rhinitis and react positive to house dust mites just like Fidalgo.

Fidalgo shows monocytosis which is seen in MCAS. Ref

"We speculate that POIS might be a psychological disorder without discarding other possibilities involving chemical imbalances in the brain or the hypothesis that modulation of the immune system can occur via neural and hormonal stimulation." Ref

Muon speculates that POIS might be a manifestation of a mast cell activation disorder without discarding other possibilities involving chemical imbalances in the brain or the hypothesis that modulation of the immune system can occur via neural and hormonal stimulation.

Fidalgo, you could ask the researchers if they got the toolset to do a proper diagnostic workup for MCAS.
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