Author Topic: POIS Paper Archive - a list of scientific articles about POIS  (Read 12958 times)

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #165 on: September 07, 2020, 11:16:45 AM »
Low serum vitamin D is associated with an increased likelihood of acquired premature ejaculation

Take a look under the vitamin D header on page 1 of this thread (serotonin).

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #166 on: September 07, 2020, 05:37:45 PM »
A new hit on scholar:

https://books.google.nl/books?hl=nl&lr=&id=3PD6DwAAQBAJ&oi=fnd&pg=PA491&dq=post+orgasmic+illness+syndrome&ots=qBmOh_TADF&sig=awkvF8f-bOt-NJwLofYvU5tZKik&redir_esc=y#v=onepage&q=post%20orgasmic%20illness%20syndrome&f=false

Anyone got access to the full article? Some pages are blocked.

Symptoms escalated due to stress. I've seen this mentioned a few times on this forum over the years. Stress seem to be a trigger. Mast cell disorders are not mentioned in the suggested theories under key messages...

hurray

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #167 on: September 07, 2020, 06:12:12 PM »
A new hit on scholar:

https://books.google.nl/books?hl=nl&lr=&id=3PD6DwAAQBAJ&oi=fnd&pg=PA491&dq=post+orgasmic+illness+syndrome&ots=qBmOh_TADF&sig=awkvF8f-bOt-NJwLofYvU5tZKik&redir_esc=y#v=onepage&q=post%20orgasmic%20illness%20syndrome&f=false

Anyone got access to the full article? Some pages are blocked.

Symptoms escalated due to stress. I've seen this mentioned a few times on this forum over the years. Stress seem to be a trigger. Mast cell disorders are not mentioned in the suggested theories under key messages...

The book is on sci-hub (chapter 33):

https://sci-hub.tw/10.1007/978-3-030-52298-8

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #168 on: September 07, 2020, 06:33:08 PM »
Thanks hurray, tried sci-hub but for some reason didn't work. Your link however is working.

"When tested between ejaculations, he was found not to have these conditions and to have an IQ of 150."

We have some polls in the poll category about intelligence and education. Dr. Bassett is located in Sheffield teaching hospitals NHS. That's where I have tested a couple of mast cell activation markers. I've sent her an email.

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #169 on: September 08, 2020, 12:17:50 PM »
I've sent her an email.

Ok nevermind, automatic reply: "I am now on maternity leave until June 2021"

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #170 on: September 12, 2020, 11:25:16 AM »
Immediate hypersensitivity to seminal fluid and atopic dermatitis

"Serum from the husband and nonrelated men also contained antigen that provoked histamine release from the patient's leukocytes in vitro. The antigen in serum was associated with the globulin fraction and had a temporal relationship to ejaculation, appearing within 12 hours of ejaculation and disappearing within four days."

It's an antigen for the woman's leukocytes but circulates in the serum of men up to 4 days? Just like the timing seen in POISers.

A new manifestation of seminal fluid hypersensitivity

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #171 on: September 17, 2020, 08:48:05 AM »
Anatomy and Physiology of Erection, Ejaculation, and Orgasm

"Through activation of specific protein kinases, protein phosphorylation leads to opening of potassium channels, closing of calcium channels".

"Neurotransmitters play an important role in regulating ejaculation. Studies have shown that activation of serotonin 5HT1A receptors promotes ejaculation, while 5HT1B delays ejaculation [ 52 ]. Activation of dopamine receptors D2 and D3 promotes ejaculation"

"While these are similar between genders, in men there is additional activation in the periaqueductal gray matter."

https://en.wikipedia.org/wiki/Periaqueductal_gray

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #172 on: September 23, 2020, 11:44:32 AM »
Table 1 Summary of the 3 clinical POIS cases.

Some of the symptoms above sound like neuromuscular transmissions problems. Here is another one regarding swallowing:
https://poiscenter.com/forums/index.php?topic=3416.msg36014#msg36014
« Last Edit: September 23, 2020, 12:22:16 PM by Muon »

quikot

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #173 on: October 02, 2020, 07:07:22 AM »
Found another POIS article, this one was published yesterday. It's behind a pay wall though, so not sure what's exactly written there...

Re: Post-Orgasmic Illness Syndrome: History and Current Perspectives
https://www.auajournals.org/doi/full/10.1097/JU.0000000000001212.02

demografx

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #174 on: October 02, 2020, 03:17:15 PM »
Found another POIS article, this one was published yesterday. It's behind a pay wall though, so not sure what's exactly written there...

Re: Post-Orgasmic Illness Syndrome: History and Current Perspectives
https://www.auajournals.org/doi/full/10.1097/JU.0000000000001212.02


quikot, thank you! (I sent to POIS Research Team)

This link enables your full viewing:

https://sci-hub.se/
Edit: sci-hub not working, trying to find out why

Post-edit: from POIS Research Team: “Sometimes it can take a day or two for papers to get uploaded to Sci-hub - they rely on folks uploading new papers as they become available so it's not automatic. Try again on Monday, perhaps?“
« Last Edit: October 02, 2020, 05:45:08 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #175 on: October 03, 2020, 07:26:37 AM »
Found another POIS article, this one was published yesterday. It's behind a pay wall though, so not sure what's exactly written there...
https://poiscenter.com/forums/index.php?topic=3127.msg35738#msg35738

New:
Analysis of the Symptomatology, Disease Course, and Treatment of Postorgasmic Illness Syndrome in a Large Sample

"Common symptoms were difficulty concentrating (254, 84%), extreme fatigue (250, 83%), irritability (225, 74%), and muscle weakness (212, 70%)."

Fatigue shows exactly the same percentage as in table 1 of Afrin's MCAD study, namely 83%:
Often seen, rarely recognized: mast cell activation disease - a guide to diagnosis and therapeutic options
« Last Edit: October 04, 2020, 02:27:32 PM by Muon »

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #176 on: October 18, 2020, 07:02:20 AM »
Paper from Natale et al. (Poiscenter survey) can now be unlocked with sci-hub: https://sci-hub.se/10.1016/j.jsxm.2020.08.020

"Conversely, the survey population included a high proportion of respondents complaining of muscle weakness, with 70% compared with just 18% of patients in the study by Waldinger et al12 and 14.3% of patients in the study by Reisman."

Waldinger (passed away) and Reisman are located in the same country, actually in the same city. Environmental and/or genetic factors could play a role here. Their numbers regarding muscle weakness are similar.

It seems Dr. Rubin had 2 success cases with antihistamines and tramadol:
https://twitter.com/jsexmed/status/1316952588718346241
« Last Edit: October 18, 2020, 09:11:32 AM by Muon »

Quantum

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #177 on: October 18, 2020, 04:11:52 PM »
Paper from Natale et al. (Poiscenter survey) can now be unlocked with sci-hub: https://sci-hub.se/10.1016/j.jsxm.2020.08.020

"Conversely, the survey population included a high proportion of respondents complaining of muscle weakness, with 70% compared with just 18% of patients in the study by Waldinger et al12 and 14.3% of patients in the study by Reisman."

As a reminder, Caleb Natale is the member of the Tulane University team who lead the survey here on POISCenter in 2019, so this paper is the one that came out from our answers.

You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

demografx

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #178 on: October 18, 2020, 08:19:29 PM »
Quantum, thanks for your teriffic work in organizing this!
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Muon

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Re: POIS Paper Archive - a list of scientific articles about POIS
« Reply #179 on: October 24, 2020, 12:54:08 PM »
Article 1

"Both men were not particularly susceptible to viral infections, such as influenza"

Overactive immune system.

"Indeed, flulike syndromes have been described as side effects of the medical use of cytokines (Vial and Descotes, 1995a, 1995b). Involvement of an immediate-type immune response, clinically represented by urticaria, can be excluded by the unresponsiveness of symptoms to antihistamines."

Mast cells release foremost cytokines/chemokines, these are more frequently involved than histamine.

"However, oxytocine has been suggested to negatively interfere with cognition (Geenen et al., 1988)."
« Last Edit: October 24, 2020, 12:58:30 PM by Muon »