Author Topic: POIS Paper Archive - a list of scientific articles about POIS  (Read 13803 times)

Muon

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Re: POIS Paper Archive
« Reply #15 on: November 22, 2019, 08:22:00 AM »
Thanks, Muon, didn’t know we could do that. You should give us an SMF tutorial! :)
You can do that for almost every software out there, it's almost a universal command, thus not bound to SMF. PDF readers, internet browsers, windows etcetera are making use of it.

Muon

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demografx

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Re: POIS Paper Archive
« Reply #17 on: November 28, 2019, 06:47:37 AM »
Thanks, Muon, sent to our POIS Research Team.
« Last Edit: November 28, 2019, 07:57:09 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: POIS Paper Archive
« Reply #18 on: November 28, 2019, 07:09:50 AM »
Good news I guess?
The problem is that my serum testosterone is actually normal high
So I don't know how to feel about testosterone treatment :/
Can we know exactly the guy's symptoms? The description doesn't sound sufficient for a POIS diagnoses.
« Last Edit: November 28, 2019, 07:11:35 AM by Nas »

demografx

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Re: POIS Paper Archive
« Reply #19 on: November 28, 2019, 07:30:56 AM »
Nas, I’ve had a theory, THAT I DON’T RECOMMEND TESTING WITHOUT CLOSE MEDICAL SUPERVISION, that TRT can also benefit some POISers with normal Free-T values. Not scientific. Call it a hunch. A POISer friend tried it and it didn’t help.
« Last Edit: November 28, 2019, 07:54:51 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Eliasjoelrivera

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Re: POIS Paper Archive
« Reply #20 on: November 28, 2019, 07:35:23 AM »
New paper:

Successful treatment of Post-orgasmic illness syndrome with human chorionic gonadotropin

interesting article. I think I will be happy to seek treatment to put it into practice. At some point I thought about using testosterone patches. But this method seems more effective. I will start consulting an endocrinologist. thanks for the info.

demografx

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Re: POIS Paper Archive
« Reply #21 on: November 28, 2019, 07:35:58 AM »
Can we know exactly the guy's symptoms?
Email the author?
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: POIS Paper Archive
« Reply #22 on: November 28, 2019, 07:40:19 AM »
I will start consulting an endocrinologist.
An endocrinologist is the *only* physician/medical specialist I consulted who actually helped me.

Ten years ago, I was advised by a Harvard biophysicist friend who pioneered & then developed some successful AIDS treatment, to seek out a *university* based endocrinologist because they are more research-oriented and thus likely to be more open to POIS evaluation & treatment. So I did.
« Last Edit: November 29, 2019, 05:28:09 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: POIS Paper Archive
« Reply #23 on: November 28, 2019, 07:43:22 AM »
Can we know exactly the guy's symptoms?
Email the author?
Sorry I didn't read the full article, yes the patient seems to be suffering from POIS evident by his social withdrawal.

demografx

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Re: POIS Paper Archive
« Reply #24 on: November 28, 2019, 07:52:36 AM »
Thanks, Nas
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: POIS Paper Archive
« Reply #25 on: November 28, 2019, 08:02:49 AM »
So can we suppose that gonadotropin treatment is similar to TRT or should we consider it as a novel treatment with a different mechanism of action?

demografx

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Re: POIS Paper Archive
« Reply #26 on: November 28, 2019, 08:02:56 AM »
Keep in mind that Dr. Waldinger’s first co-author is an endocrinologist. Even 10 years ago, I was successful in persuading my endocrinologist to take me seriously by pointing this out.

As Quantum often suggests, I showed him the Waldinger+endocrinologist article from 2002.
« Last Edit: November 28, 2019, 11:37:42 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: POIS Paper Archive
« Reply #27 on: November 28, 2019, 08:04:03 AM »
So can we suppose that gonadotropin treatment is similar to TRT or should we consider it as a novel treatment with a different mechanism of action?
I would ask an endocrinologist.
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: POIS Paper Archive
« Reply #28 on: November 28, 2019, 08:10:36 AM »
I don’t know anything about them (NYU docs sound promising), but I considered a similar online chat with an endocrinologist:
Chat with an endocrinologist:
https://tinyurl.com/rq28vrt
« Last Edit: November 29, 2019, 05:33:31 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Muon

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Re: POIS Paper Archive
« Reply #29 on: November 28, 2019, 04:08:45 PM »
My mother, her sister and my grandmother who got health problems all felt better during pregnancy. Take a look at this:
https://en.wikipedia.org/wiki/Human_chorionic_gonadotropin#Reference_levels_in_normal_pregnancy

Theoretically, both desensitization and TRT are able to stabilize mast cells:
https://poiscenter.com/forums/index.php?topic=2301.msg31643#msg31643

By applying hCG they could have expanded his Treg pool by stimulation of androgen receptors. See links about androgens and Tregs inside this thread: https://poiscenter.com/forums/index.php?topic=2891.0

It would be of interest to know what his FOXP3+Treg numbers were before and after hCG treatment. The outcome of this 'treatment' is very encouraging but don't forget that this is only a case report so far and his POIS has not been completely reversed from what I understand despite having a high T level after application.

Some other papers which might be of interest:

Serotonin secretion from rat Leydig cells

Human adrenal cortex hyperfunction due to LH/hCG
« Last Edit: November 28, 2019, 04:39:04 PM by Muon »