Author Topic: POIS CURED (Read 6659 times)

happy2 · « **on:** September 14, 2019, 05:23:46 AM »

POIS, gone. Until you guys realize this is an allergy you will keep spinning your wheels. I'm cured, used to take antihistamines, for 5 years when my system hypodesensitized itself to the reaction, now I'm cured, haven't taken anything since February 2018.

Muon · « **Reply #1 on:** September 14, 2019, 08:15:50 AM »

Quote from: happy2 on September 14, 2019, 05:23:46 AM

Until you guys realize this is an allergy...

Or MCAS. This could be true in your case but that doesn't mean it's true for POIS in general, that's the main problem we are dealing with here.

Sounds to me you have stabilized mast cells. Perhaps keeping mast cells calm for a long period of time gives the body room to desensitize itself. Not sure if I have asked this before but have they found elevation of IgE? If not then you could rule out a type 1 allergy. If POIS is a symptom of MCAS we probably will not find any greatest common divisor by research until MCAS research itself progresses.

b_jim · « **Reply #2 on:** September 14, 2019, 01:39:47 PM »

Very nice job.

Iwillbeatthis · « **Reply #3 on:** September 14, 2019, 03:54:26 PM »

So what did you actually do to cure yourself?

Nas · « **Reply #4 on:** September 14, 2019, 04:02:28 PM »

So anti-histamines work for you?

Muon · « **Reply #5 on:** September 14, 2019, 04:09:00 PM »

Quote from: Iwillbeatthis on September 14, 2019, 03:54:26 PM

So what did you actually do to cure yourself?

Quote from: Nas on September 14, 2019, 04:02:28 PM

So anti-histamines work for you?

Look up his older posts.

Nas · « **Reply #6 on:** September 14, 2019, 04:13:37 PM »

Quote from: Muon on September 14, 2019, 04:09:00 PM

Look up his older posts.

Ok yeah anti-histamines work for him, which don't work for me.
We really need lab evidence for the claims of many people in this forum who claimed "a cure".
I'm beginning to think that SOME people claiming to have POIS are curing themselves psychologically. Only lab tests can prove the legitimacy of their claims.

FernandoPOIS · « **Reply #7 on:** September 18, 2019, 08:27:24 AM »

Everyone who has this condition needs to find the chronic problem that is leading to POIS. In the case of our friend who got the cure, he had a chronic allergy and got the cure by treating the allergy. In my case that I have chronic spinal pain, I get no symptoms if the spine is painless and well strengthened. Some cases involving nerve damage, fungal infections, rheumatologic problems are harder to find a cure.

Scrub · « **Reply #8 on:** September 18, 2019, 04:26:19 PM »

Antihistamines have never worked for me.

swell · « **Reply #9 on:** September 20, 2019, 03:19:48 AM »

It will get fixed if you take various growth factors on a sustained basis - 3, 4 months at least. POIS is our body entering a freeze/hibernation state and I believe the culprit being a thin epithelium layer in veins and mucus lining. Semen is a heavily protected substance as it travels through vas deferens etc, and the thin epithelium (like leaky gut) is prone to cause reactions, various symptom manifestations that POIS'ers get. I dont want to boast, but I fortunately now feel even better after ejaculation (like normal people).

Quote from: FernandoPOIS on September 18, 2019, 08:27:24 AM

Everyone who has this condition needs to find the chronic problem that is leading to POIS. In the case of our friend who got the cure, he had a chronic allergy and got the cure by treating the allergy. In my case that I have chronic spinal pain, I get no symptoms if the spine is painless and well strengthened. Some cases involving nerve damage, fungal infections, rheumatologic problems are harder to find a cure.

ElVelero · « **Reply #10 on:** September 20, 2019, 05:09:51 AM »

So, only by taking antihistamines you got cured?

dizzy · « **Reply #11 on:** September 20, 2019, 05:56:16 PM »

I scanned through happy2's posts, and it seems this was the protocol:

Quote

I would focus on taking Zyrtec for an extended period of time, then take 50mgs of Benadryl immediately following O. This worked for me. You may want to load up your first time trying it to say 20mgs of Zyrtec the day of, and 75-100 mgs of Benadryl immediately after O.

Unfortunately, Benadryl is not available in my country (Netherlands), so I can't test this.

dizzy · « **Reply #12 on:** September 20, 2019, 07:07:51 PM »

I may have found some interesting connections here. This article [1], titled The role of antihistamine therapy in vascular headaches, proposes that histamine and migraine attacks are related.

Quote

Migraine (vascular) headache is a complex syndrome that involves vascular hyperreactivity.
...
it has been demonstrated fairly conclusively that increased histamine levels correlate with migraine attacks in susceptible persons.
...
Vascular (migraine) headache is an idiopathic dis- order associated with disturbances of the vascular sys- tem.

This is relevant because some have already made the connection between POIS and migraine. Others have made a connection between POIS and vascular system (e.g. niacin which causes vasodilation). And then there is the connection between migraine and histamine.

But beware, some counter-evidence is given here: [2]

[1] https://www.jacionline.org/article/S0091-6749(05)80239-8/pdf

[2] https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-019-0984-1

dizzy · « **Reply #13 on:** September 22, 2019, 10:17:52 AM »

Article:

Research has found that vitamin D supplementation in conjunction with anti-histamine and systemic corticosteroid use produces an elevated response in resolving the symptoms of chronic urticaria (chronic hives).

https://www.vitamindcouncil.org/research-discovers-vitamin-d-supplementation-in-conjunction-with-standard-treatment-may-improve-chronic-hives/#.XYeQIvexVeg

dizzy · « **Reply #14 on:** September 22, 2019, 10:25:44 AM »

Another interesting post related to histamine here:

https://www.reddit.com/r/NoFap/comments/3uqjbx/pmo_and_histamine_this_might_change_your_life/

Quote

(...)
Many users on these forums report that their POIS symptoms are due to inflammation and they find relief of their symptoms with NSAIDS and anti-inflammatory meds (personally, naxopren works wonders for my symptoms).

Another finding was that vitamin B3, or Niacin, helped relieve the forum members of up to 80% of their symptoms! This was a breakthrough for me, so I put it to the test (sorry nofap, but it had to be done). I popped 400mg of niacin 20 minutes before an MO, waited for the flush and then popped another 400mg along with some NSAIDS. Safe to say I didn't feel tired or as worn out as I usually do post-O. The next day? My head was clear, no brain fog, I felt well rested with the energy and vitality I hadn't felt in months!

I kept researching Niacin and why it was so effective. I found out niacin flushes out the histamines and toxins in my your body. What role does histamine play in nofap? After any kind of sexual stress (ahem, PMO) your basophils release histamine, which is broken down by an enzyme called Diamine Oxidase (DAO).

I'm still a rookie to this research, but due to a few genetic mutations in the population, some people have low levels of this DAO enzyme which causes histamine to build up in the body, eventually reaching the brain and causing symptoms of brain fog. Those who can't process histamine properly in the body are known as "histamine intolerant"

A person with histamine intolerance usually had other problems aside from high histamine build up. These people also can't process vitamin B-12 and folic acid (which release histamine in the body) as well as high histamine foods, or at least that seems to be the case so far.

Anecdotally, ever since I've eliminated high histamine foods and introduced mast-cell stabilizers that control the release of histamine, my brain fog has been non-existent.

News:

Author Topic: POIS CURED (Read 6659 times)