Author Topic: Sjögren's syndrome  (Read 9700 times)

mike_sweden

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Re: Sjögren's syndrome
« Reply #30 on: January 08, 2021, 10:41:33 AM »
Sj?gren was a Swede! :-)

Muon

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Re: Sjögren's syndrome
« Reply #31 on: February 25, 2021, 03:40:10 PM »
Intestinal B cell-activating factor: an indicator of non-IgE-mediated hypersensitivity reactions to food?

High levels of BAFF have been reported in patients with allergic disease (asthma) and autoimmune diseases such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, systemic sclerosis, mixed cryoglobulinaemia, myasthenia gravis and coeliac disease.12-16 Overexpression of BAFF in animal models leads to B-cell hyperplasia, lymphoproliferation, hypergammaglobulinaemia and symptoms of autoimmunity.

Muon

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Re: Sjögren's syndrome
« Reply #32 on: March 11, 2021, 11:27:36 AM »
Pathophysiologic role of Interleukin-33/ST2 in Sjögren's syndrome

• in pSS, IL-33 is released from damaged epithelial salivary cells

• in pSS, IL-33 exhibits a dual role as alarmin as well as a pro-inflammatory cytokine

• IL-33 might work as a central actor in initiating a vicious auto-inflammatory loop


Is the 3rd point true for POIS?