Transiently Induced Immune Deficiency and Therapy

[berlin1984]

He was also very skeptical about the benefits of IV Vitamin C generally speaking,

I liked it. I felt it killed off something in my body. But I stopped after 3 times because of money and logistics..

https://www.google.com/search?client=firefox-b-d&q=vitamin+c+as+antiviral

[Iwillbeatthis]

I saw improvements straight away with the immuno complex, I remember when I first tried I had some itchiness and rashes in groin but it didn't really make me feel ill. The copper gluconate on the other hand did make me feel bad like bad brain fog and nauseous however I did see improvements as time went on and I was less reactive to it. I remember on the immuno complex I did feel nauseous during POIS. I need to try the therapy again because I feel like all the progress made has been reset. I never did iv vitamin c also.

Nanna, trying your protocol and the immuno complex is hitting hard only after two days with symptoms of headache, brain fog, and insomnia. Should I layoff until symptoms subside and restart then?

Hey Nanna, just wanted to share that I’m beginning to feel really good - perhaps the best I’ve felt in 10 years. I also feel like this treatment is addressing the root cause and not just the symptoms. It’s been 2.5 months on your treatment. Thanks!

Similarly I went through 2 or 3 bottles before seeing significant improvements, along with the other supplements. As Nanna recommends I'll try to continue through 6 months and evaluate on the way.

Great to hear. May I ask how long you got bad feelings from taking it? When did headache etc stop?

Did you ever notice this kind of pattern from other supplements?

(I sometimes feel bad in morning from taking supplements, especially when taking them in late in evening and I'm now wondering if this is a similar effect that you get, something is killed off but can't get flushed out)

Same question (and congrats) to Iwillbeatthis

[Mushnikk]

I believe this theory to be true for me also...during a cold my POIS is diminished and immune stimulating nutrients like vitamin C / copper / zinc make me fatigued. Plus I can link the start of my POIS to a time of immense psychological stress that probably manifested a viral infection.

I will try the protocol, thank you for all your input!

I got to be honest that I am somewhat skeptical about AHCC. It is a patented product and all studies seem to be financed by the company producing it. There seem to be other immunstimulating natural compounds out there - is there a specific reason to choose AHCC?

Other immunstimulating compounds I came across in my research:

Echinacea
L-Theanine
Astragalus
Cats's Claw
Neem Oil
Chitosan

[Prospero]

Hi nanna1,

I posted in this thread the results of my two experiences with the opioid Tramadol, which I took immediately after O. Short story: I had no POIS symptom the first time, and the second time I got a serotonin syndrome in the following hours but not the usual POIS symptoms.

I wonder if, in your opinion, there could be a link with Jiang, Yin & al.'s thesis regarding mu-opioid receptors, and with your own theory.

Of course there may be many possible explanations for the success of Tramadol.

https://poiscenter.com/forums/index.php?topic=3551.msg38184#msg38184

Codeine has the same positive effect as Tramadol for me. Two cheers for the Chinese Doctors Hypothesis... or for nanna1's, as far as I know.

Update : I tried to take Codeine (+Paracetamol) rather than Tramadol, immediately after O. I had many anxiety symptoms during the first hour, for some reason (psychological or else), then they vanished. And... absolutely no POIS symptoms. So, it seems quite sure now that my success with Tramadol was not caused by its SNRI properties.

[berlin1984]

Hello guys, some feedback after getting 1st shot of Sputnik V vaccine yesterday in Moscow, Russia: I had chills and mild fever overnight which was alleviated with paracetamol, now some residual fatigue left, doctors warned that it may last a couple of days. They also told that the more acute the body reaction is - the more antibodies are subsequently produced. Second vaccine shot must be done in three weeks.

But what?s curious in relation to POIS and has already been pointed out before by other forum members: prior to vaccination I was still in the middle of POIS cycle (2-3 days after last O, normally lasts 7+ days for me) and after getting the vaccine and feeling first side effects I have simultaneously felt POIS symptoms to diminish (muscle pains and tension decreasing, brain fog subsiding except for the fever effect). So another case confirming that while being ill and having our immune systems boosted helps get rid of POIS. It goes contrary with Waldinger?s auto-immune theory as amplification of immune reaction obviously helps us battling POIS, rather than as it was assumed by Professor that immune system attacks our own body.

Assuming this being not just mere coincidence of our conditions improving following immune system boost it poses a question: is POIS a dormant infection or virus that gets activated following O that normally doesn?t trigger activation of our immune systems?

[Iwillbeatthis]

I started Sulforaphane (broccoli sprout powder) two days ago and I am seeing massive improvements from it in terms of inflammation and autistic symptoms, I got some pains and a few rashes as if its killing some infection/pathogen in my body. I feel really good in my head from it.

This supplement is incredibly unique and powerful, it turns on the nrf2 gene which combats oxidative stress and unlike most antioxidant supplements there is actually a lot of scientific studies to back up the benefits of Sulforaphane.

PS: If you know the doctor; Rhonda Patrick from the Joe Rogan podcasts this is the supplement she is always banging on about.

[Muon]

PS: If you know the doctor; Rhonda Patrick from the Joe Rogan podcasts this is the supplement she is always banging on about.

You can find two of her papers about vit D in the paper thread.

[berlin1984]

I started Sulforaphane (broccoli sprout powder) two days ago and I am seeing massive improvements from it in terms of inflammation and autistic symptoms, I got some pains and a few rashes as if its killing some infection/pathogen in my body. I feel really good in my head from it.

This supplement is incredibly unique and powerful, it turns on the nrf2 gene which combats oxidative stress and unlike most antioxidant supplements there is actually a lot of scientific studies to back up the benefits of Sulforaphane.

I'm homozygous for the sod2 rs4880 gene, (super oxide).

When I had this chronic infection from 2018-2019, I would wake up feeling like death in the mornings, the worst brain fog, autistic symptoms, feeling brain dead and l arginine cleared it so that indicates it was some type of nitric oxide/oxidative stress disorder. I still have this going on sometimes outside of POIS but much less severe.

I've tried lots of things to combat oxidative stress: NAC, liposomal glutathione, exercise, agmatine sulfate, l arginine and in the end most weren't very helpful.

However Sulforaphane doesn't compare to any of these things above and it is a game changer for me so far.

Congrats. I noted it on my list of stuff to try. Please update us in a few days/weeks if there is more good changes and also if there is some bad changes.
What's your dosage?

I see it is mentioned on this CFS forum too : https://forums.phoenixrising.me/search/?q=sulforaphane&o=date

EDIT: Haven't researched in detail, but this sounds like it's a herbal antibiotic: https://www.healthrising.org/forums/threads/histamine-intolerance-understanding-the-science.4019/#post-15924

[Iwillbeatthis]

Congrats. I noted it on my list of stuff to try. Please update us in a few days/weeks if there is more good changes and also if there is some bad changes.
What's your dosage?

I see it is mentioned on this CFS forum too : https://forums.phoenixrising.me/search/?q=sulforaphane&o=date

EDIT: Haven't researched in detail, but this sounds like it's a herbal antibiotic: https://www.healthrising.org/forums/threads/histamine-intolerance-understanding-the-science.4019/#post-15924

I'm taking these cheap 1000mcg capsules twice to three times a day which are supposedly  0.4% sulforaphane
https://ebay.us/xXY6Ly

However Dr Rhonda Patrick said studies found that most supplements on the market contained no or very little sulforaphane as it's a very unstable substance. One of the ones which was found to have good amounts of sulforaphane and used in studies was Prostaphane - https://ebay.us/1tIRud, however this is much more expensive than the one I bought. I might try it to see if theres any difference.

I wasn't aware of any bad effects until I saw the link you posted, so maybe I should be more careful. It's strange Dr Rhonda Patrick didn't mention any of these...