Developed POIS after antibiotic use

[Simon66]

I'm still able to eat a lot more foods without triggering scary symptoms. I'm now wondering if the cause of my improvement was an L. Reuteri probiotic called "Biogaia Protectis baby".

I thoroughly recommend people read the following article about L. Reuteri, I'll summarise some of the key points but it's really fascinating what this probiotic can supposedly do for people with ill health:

Role of Lactobacillus reuteri in Human Health and Diseases

Abstract
Lactobacillus reuteri (L. reuteri) is a well-studied probiotic bacterium that can colonize a large number of mammals. In humans, L. reuteri is found in different body sites, including the gastrointestinal tract, urinary tract, skin, and breast milk. The abundance of L. reuteri varies among different individuals. Several beneficial effects of L. reuteri have been noted. First, L. reuteri can produce antimicrobial molecules, such as organic acids, ethanol, and reuterin. Due to its antimicrobial activity, L. reuteri is able to inhibit the colonization of pathogenic microbes and remodel the commensal microbiota composition in the host. Second, L. reuteri can benefit the host immune system. For instance, some L. reuteri strains can reduce the production of pro-inflammatory cytokines while promoting regulatory T cell development and function. Third, bearing the ability to strengthen the intestinal barrier, the colonization of L. reuteri may decrease the microbial translocation from the gut lumen to the tissues. Microbial translocation across the intestinal epithelium has been hypothesized as an initiator of inflammation. Therefore, inflammatory diseases, including those located in the gut as well as in remote tissues, may be ameliorated by increasing the colonization of L. reuteri. Notably, the decrease in the abundance of L. reuteri in humans in the past decades is correlated with an increase in the incidences of inflammatory diseases over the same period of time. Direct supplementation or prebiotic modulation of L. reuteri may be an attractive preventive and/or therapeutic avenue against inflammatory diseases.

Source: https://www.frontiersin.org/articles/10.3389/fmicb.2018.00757/full

Here's some of the points I really liked:

• In babies born by Caesarean, gut bacteria was different to those born by natural birth. Giving Caesarean-born babies Lactobacillus Reuteri probiotics shifts their gut bacteria toward that of natural-birth babies. The vagina contains mostly Lactobacilli bacteria so Caesarean babies may miss out on getting some important bacteria and who knows how that affects them in later life.
• L. Reuteri seems to shift cytokines favourably which reduced systemic inflammation and autoimmune antibodies.
• L. Reuteri improves gut barrier integrity and decreased the amount of toxins entering the body through leaky gut.
• Males seemed to benefit less from L. Reuteri than female or castrated male mice. This suggests that there is a link between sex hormones and gut bacteria, perhaps testosterone interacts with L. Reuteri somehow.
• Some strains of L. Reuteri can produce vitamins like B12 and Folate.
• Each strain of Reuteri has different effects, it may be beneficial to combine several Reuteri probiotics.
• L. Reuteri could have an effect on obesity, it depends on the strain. More research needs to be done before conclusions can be made.
• In a mouse study, mothers that ate a high-fat diet were more likely to have offspring with social deficits similar to autism. In these affected offspring, L. Reuteri was found to be 9 times lower than normal mice. Supplementing the autistic mice with L. Reuteri, fixed a lot of the social deficit.
• L. Reuteri has an effect on neurotransmitters like GABA and oxytocin (oxytocin is related to sexual reproduction and social interaction). People with mood disorders and anxiety should look no further than their gut bacteria.
• Retinoic Acid (a metabolite of Vitamin A) boosts Lactobacilli and improves symptoms in Lupus patients. Taking the Retinol form of Vitamin A did not produce such benefits which is a bit confusing. So "All-trans-retinoic acid" is supposedly the one that works. L. Reuteri in combination with retinoic acid may be an effective way to reduce Lupus severity.
• Emerging evidence suggests that the host microbiota and immune system interact to maintain tissue homeostasis in healthy individuals.

[Hopeoneday]

Thanks Simon, usefull info.
I am trying to " playing with probiotic again", in the past i did
tryed only one or two strains probiotics, but now, i am trying
multiple strains together, and diffrent tipes.
Alsou i am traying to adjust diet, remowing foods that
i cant digest well, wheet-breads(giving me reflux , gerd).

[Simon66]

Thanks Simon, usefull info.
I am trying to " playing with probiotic again", in the past i did
tryed only one or two strains probiotics, but now, i am trying
multiple strains together, and diffrent tipes.
Alsou i am traying to adjust diet, remowing foods that
i cant digest well, wheet-breads(giving me reflux , gerd).

If you want my advice, I would stick to single strain probiotics like Rhamnosus GG, BioGaia (Reuteri) or BB536 (Longum). I think probiotics with more than one bacteria are not good for the gut because the strains can clash with each other. If you are a patient person, take only one strain for a week and see if things improve. I ran out of patience, I kept changing probiotics each day and now I don't know which one helped me. It seems like some probiotics don't help until taking them for 1 or 2 weeks so it requires a lot of patience. I keep a diary of what probiotic I am taking each day and my symptoms so I can figure things out.

[Simon66]

The struggle I'm having is I believe I have some imbalance in my body but I'm not sure if it is bacterial or fungal. I'm thinking it is fungal because I react badly to fungal foods like nutritional yeast, blue cheese and mushroom supplements. I also have a lot of skin problems, I get very itchy and sometimes have a burning sensation.

I am now revisiting Garlic supplements for their anti-fungal properties. I took the following 2 products yesterday:
1. Lindens Super Garlic
2. Allicin Max

Overnight, my sleep was very disturbed and I experienced an uptick in my symptoms including pain around my body. I'm really hoping this is a herxheimer reaction i.e. die-off of yeast overgrowth. I will continue to take these garlic supplements daily for one to two weeks. I took these garlic supplements a few months back for 2 days at a low dose and don't remember having such a severe reaction, it could be the reason my food intolerances have improved so much. The one improvement I've had from the garlic so far seems to be much lower sugar cravings which does seem to indicate I've been dealing with yeast overgrowth.

One of my symptoms that has been absent for a few months is a scary pain in my eyeballs, this symptom returned after taking the garlic pills yesterday. I am wondering if I have systemic candidiasis and the eye pain is perhaps ocular candidiasis.

Here's a very interesting article about an elderly woman who suffered from eye pain and a lot of metabolic issues, her blood was cultured for yeast but nothing was detected. Her eye doctors seemed to be very competent, although they couldn't find any specific issues, they referred the patient to a retinal specialist who performed a vitrectomy (removal of the vitreous gel in the eye) and presumably the vitreous was cultured to identify a yeast infection. The main point I take from the article is that yeast overgrowth is incredibly difficult to detect with today's testing, they had to remove the jelly from this woman's eyeballs in order to identify the problem. She took fluconazole to treat the yeast.

https://www.reviewofoptometry.com/article/the-damage-candida-can-do

I saw an opthamologist for my eye pain and floaters, he did some testing but never identified any issue. I know the eye has its own microbiome and perhaps antibiotic use allows fungi to take over. When I took Metronidazole, I developed a burning mouth with ulcers and itchy welts around my mouth but doctors couldn't culture any fungi from a swab. I later developed severely itchy folliculitis of my scalp and again the lab couldn't culture anything so there's something really inadequate with swab testing. I managed to culture it on my own agar petri dish but had no way of getting it analysed, frustratingly.

I am stopping my probiotics for now as I don't know of any probiotic that can defeat a systemic yeast overgrowth. On another note, I've also been reading a bit about prostate cancer and the blood test that accompanies it called the "PSA test", apparently garlic lowers PSA levels so I wonder if yeast overgrowth is a main cause of prostate cancer development.

[Muon]

Garlic contains a high concentration of FODMAPS by the way. I have been tested for a systemic Candida routine (by world leading doctors) but there is no evidence of systemic defects (this doesn't rule out an intestinal fungal overgrowth which is impossible to detect). The cultures taken are very prone to contamination. I also did a PSA test which was normal.

During my desenz I had moments short after subcutane injections where I felt completely normally. My oral mucous mebrane developed fully, muscles were stronger and I once ate something during this state which I could not tolerate normally and had zero reactions. This state is short-lived and could not be maintained. Sperm is a soup of immune modulators, it's unknown what mechanism is involved here.

I had severe eye pain in the past but I'm in a better state now as far as eye pain is concerned. If it was candida wouldn't it have progressed by now? Every local fungal infection I've had (skin, mouth) progressed without intervention.

[Simon66]

I seem to be doing okay with garlic, I think it takes at least 1 week to see noticeable improvements so I will update in future. The bad reaction on the first night has now lessened so I guess it was a die-off reaction.

Muon,

I don't know about progression of fungal infections, I think they are opportunistic and spread to different organs when antibiotics kill off bacteria and damage the immune system. It seems to be nearly impossible to detect candidiasis when it's hiding in internal organs.

I will provide an update on these garlic pills after a week, I am taking only the AllicinMax capsules now, at least 4 per day currently. The positive results so far seem to be lower sugar cravings. I also went shopping today and had one of those rare days when I have low anxiety and high confidence. I still feel quite fatigued so either I'm herxing from a gradual die-off or garlic is making other things worse. I may add some other antifungals like acidophilus and coconut oil if the garlic doesn't do anything.

[Simon66]

I've been looking for peoples' experiences of Garlic and found a really interesting poster on another forum. The poster is called "thebigpeatowski", here's a link to one of their threads:

https://raypeatforum.com/community/threads/the-best-of-times-the-worst-of-times.3340/page-9

Here are some quotes that I found interesting:

June 27 2014
Looking back: I discovered RP in mid-October of last year. I decided to make some HUGE changes in my life, I closed my business and moved to the country in November. By December I was seriously studying RP, applying all that I could learn and solely focusing on my health. I saw some improvements in many areas of my life(sleep, stress, PMS, hormones, etc.) and so I kept at it. However, some aspects of my health did not improve, and in fact declined RAPIDLY. These were my digestion, weight and skin. Everyone around me was like "what the hell?". By March I was a complete wreck on the inside (emotionally and intestinally) and on the outside (MAJOR ACNE and body fat). I took pictures of myself in December and March, the difference is absolutely striking....harsh winter indeed!!! My poor digestion became quite noticeable right around JAN/FEB... I remember worrying that I would have diarrhea at a Super Bowl party I was attending, so I just didn't eat.

My firm belief is that you're health is only as strong as what you digest and absorb. I can put boatloads of densely nutritious food down my throat, but if I cannot digest and absorb those nutrients it does me NO good. I have been wracking my brain trying to figure out WHY my digestion suddenly tanked on me. Was it food allergies? Histamine intolerance? Cancer?

While I did have adult hormonal acne prior to Peating, I did not have the atrocious acne that ensued after adding more carbs and dairy into my diet. I think the Progest-E and extra vitamin A have been responsible for a lot of my skin clearing. But removing dairy seems to be adding even more benefit. I am very much saddened by this and I hope that when my digestion gets better I will be able to add dairy back into my diet. For now, I am thoroughly enjoying my clear skin DESPITE STILL HAVING POOR DIGESTION.

I did not have this much excess body fat prior to Peating (gained 25 pounds Peating). The only things I changed from my previous diet were: severely restricting PUFA, swapping fruit for vegetables, adding much more dairy and swapping sugar for stevia in my coffee. Since June 1st I have had NO dairy and have lost a good bunch of weight in addition to my lovely clear skin.

I did not have chronic diarrhea prior to Peating. While I did have bowel issues, they leaned more towards constipation with only occasional diarrhea (once every couple months, never lasted for more than a few hours). On June 1st I started a very intense effort an trying to figure out which foods were causing me problems. I still have diarrhea, so it isn't the dairy because I have not had any. In fact I still can't seem to pinpoint it to any particular food as I have stated so many times before. Massive food elimination is not helping my chronic diarrhea. Histamine avoidance was also a dead end, made no difference at all. I have only tried the DAO enzymes once and so I can't really give any feedback on those.The carrot salad has helped with estrogen, but does not help with chronic diarrhea.

My doctor diagnosed me with IBS and wants me to go to Seattle and get tested for SIBO at Children's hospital. it takes several weeks to get an appointment and I am not entirely sure what that diagnosis will tell me that I don't already know. I firmly believe that my long and excessive history of antibiotic use is responsible for the gut dysbiosis that I am experiencing, so I will not take more antibiotics to merely put off the inevitable.

So now I am trying massive doses of raw garlic instead of antibiotics. I am hoping to eradicate what ever microbe is causing me duress. I also wonder if adding carbs caused this gut imbalance or perhaps I have had it all along, but kept it at bay with various supplements and starvation while low-carbing??? Maybe I picked up an infection? I just don't know... the garlic is BRUTALLY VILE, I don't recommend it to anybody unless you are desperate like me.

One other option is some sort of pancreatic insufficiency...I have not looked into this one much. If the garlic does not bring some sort of balance then I will explore this avenue further.

July 9 2014
QUICK UPDATE: My Garlic Shock & Awe treatment worked like a charm. Total MAGIC!!! Absolutely NO diarrhea, perfectly normal brown BMs and transit time.

This leads me to believe that I had some sort of serious gut flora imbalance, not sure how I acquired it, but raw garlic being a broad spectrum antibiotic has worked miracles. I am thinking that the Cyproheptadine did not work because it never addressed the underlying dysbiosis, which in my case was EXTREME. Perhaps because I struggle with hypothyroidism my immune system was not able to eradicate it on it's own.

All of my crazy food elimination schemes led absolutely no where. I kept coming to the same conclusion over and over: that it did not matter what I ate, it ALWAYS ended in yellow diarrhea. I knew the problem was ME and it got progressively worse with each passing week. However taking plenty of thyroid meds and carrot salad WAS NOT fixing the problem, I needed something MUCH stronger.

It got a bit scary as I entered a tail-spin of sorts: I became afraid to eat because every time I put something in my mouth it triggered diarrhea. Yet the less I ate the more my temps dropped, metabolism was sh*it and severe depression set in.

Since the chronic diarrhea has stopped I have had an ENORMOUS surge in energy and mood/happiness. Really unbelievable actually. I feel like I have my life back and can make plans and actually get stuff done....like I am not being poisoned anymore. Amazing.

My personal conclusion is that we all have gut flora, no matter what we try to do to eradicate it we can't, it's here to stay. In my experience, not all intestinal bacteria are friendly, some species seem to be much nicer than others. When the balance gets out of whack and severe dysbiosis sets in, it can cause inflammation which causes all kinds of food sensitivities and an increase in the release of serotonin. This mimics many different illnesses and can become very difficult to pinpoint.

For me, specific foods were not the trigger, although I still don't eat starches. Lowering serotonin with Cypro did not fix the CAUSE of my gut inflammation. Stopping the inflammation by kicking the hell-raising microbes OUT has resulted in lowered serotonin, I can tell by the way I feel. Happy/peaceful/positive/calm/fearless/love for everyone...etc. etc. etc.

AND I am THRILLED that I can eat again!!! I love to eat....At first it felt quite strange to actually use my colon again, after months of pure liquid the sensations of bulk were sorta strange....Really truly, you have NO idea how happy I am... :woo

Also, my skin is flawless...FLAWLESS! As in I went through this last cycle with not one zit!!! NO huge painful cysts, I can't remember how long it's been since that has happened, since I was on Accutane in college maybe? Thinking hell-raising gut flora might contribute to acne as well...

Oh, I wanted to add one more thought: I think my former (pre-Peat) High Fat/Low Carb diet DEFINITELY set me up for dysbiosis. I'm pretty sure that our intestinal lining needs sugar to be healthy/resistant to pathogenic bacteria. I also think that having inflamed guts in the presence of a higher fat diet (even healthy saturated fat) can contribute to endotoxin poisoning. For me, lowering my fat intake until my guts healed I think has helped with acne. I had loads of butter on my lobster last night and seem to be fine today.....mmmmm butter, Oh how I missed thee!!!

July 14 2014
I was desperate and so was willing to try ANYTHING. My diarrhea would go away for a bit and just when I thought I was done with it, it would start all over again. It got progressively worse with each passing month and I was feeling so defeated and depleted, I knew I had to take severe measures. Given my personal history of antibiotic use, I suspected that what ever sort of microbes I was hosting might be antibiotic resistant. The raw garlic was an easy and cheap way to test my theory. I took several cloves of raw organic garlic (close to 5 grams per dose) and pressed them with a garlic press into a small drinking glass, added a couple oz. of cold water and let it sit for a minimum of 15 minutes to let the enzymes develop. I drank this concoction (including eating the clove bits) three times a day for a week. It was brutal and I don't recommend it unless you are at your wits end. I had gut churning nausea, headaches, swollen lymph glands, itchy ears and fatigue for 4 days. I felt like I was coming down with the flu and thought that surely I had poisoned myself....TMI alert: What came out of me on day four was unlike any diarrhea I had previously experienced...and with that I suddenly felt better than I had in years. My depression lifted, my guts were calm and my stomach was flat. I had a mental clarity that I had not felt in as many years and I KNEW I was cured. Since then my energy has become steadily better with each passing day. No doubt due to my ability to ACTUALLY digest and assimilate nutrients from my food now.

My situation was extreme. I have scoured this website and others looking for someone who has actually had a ruptured appendix AND a long history of antibiotic use, I could find not find any fellow Peatians with similar gut issues. I understand that what I did was not part of a Peat type protocol, which is precisely why I am not recommending it. However, if it can help someone with SIBO or some sort of gut dysbiosis then I certainly want to pay it forward and share my personal experiment/experience.

I truly believe that anyone who struggles with a sluggish thyroid, has used antibiotics, birth control pills or other pharmaceuticals, experienced long term unrelenting stress or poor diet might suffer from a microbial imbalance.....just my two cents :2cents

Thanks Katty! I read about the flowers of sulfur and wanted to try it, but in the end it was easier for me to find raw garlic. I took it three times a day for a week and yes, the turning point was day 4. I guess the enzymes in raw garlic are actually able to dissolve bacterial biofilms and kill pathogenic yeast as well. It was the longest smelliest week of my life and COMPLETELY worth it.

August 20 2014
Yes I added dairy back in, no problems whatsoever, thank goodness!!! I went slowly with coffee and made sure that it had lots of milk and sugar and just a little at a time, again no issues and I can drink lots now. I was very nervous adding foods back in at first, but I have had no problems except with a pork fat salame bender that I went on which resulted in greasy skin and breakouts. No diarrhea since late June. I do get occasional bloating and have noticed the brain issues occur at the same time, so now I'm completely convinced they are related.

Oregano oil was not broad spectrum enough for me, same goes for coconut oil, carrot salad and apple cider vinegar. They all work to a degree and I still use them (I don't use oregano oil internally since starting Peat), but my situation was extreme and I couldn't wait around. I had been fiddling with food elimination and various tweaks for months and my diarrhea was getting worse with each passing week/month. I felt like I was starving. I needed something really strong and broad spectrum to give my guts a chance to find balance. Massive doses of raw garlic was a miracle for me. It did make my stomach hurt for five to ten minutes following ingestion, but only the for the first three days or so. Whatever microbes were raising hell are now quietly behaving.

I think I will do an Activated Charcoal Reboot once a week, on Sundays because that's the day that I take a break from any supplements. I'll also use it on an as needed basis if I get bloated again.

Interestingly, the poster took Metronidazole (a strong antibiotic that targets the gut) and had a similarly bad reaction to me:

May 16 2015
Hi moss...so you took Metronidazole and had these symptoms too?

It's been three months (exactly to the day) since I took that wicked med. All of my brain/tinnitus/gut issues are much better, but it's a super slow recovery for sure. I wouldn't be this far along without Nystatin and certainly would NOT be able to party properly on Cinco de Mayo without major repercussions. :lol:

At any rate, I'm done with GI docs. Even the forward thinking ones that do fecal transplants will not believe in Candida overgrowth of the bowel.....an utter waste of time for sure.

One random thought I had was this: (and please keep in mind that I know NOTHING about the immune system) What if a person had developed an allergy to yeast? Maybe that could be an exacerbating factor towards this normal commensal organism....I don't have AIDS/HIV so I'm still trying to figure out why MY body does not get this under control on it's own/quicker....or why it's so easily thrown out of balance, if that makes any sense.

[Simon66]

I took the Garlic for about 4 or 5 days and saw no improvements, I actually started breaking out in acne as well.

The supplements that have helped me so far seem to be anti-fungals. I'm currently retesting Colostrum LD, L-Arginine & Acidophilus.

[Simon66]

I believe Garlic really messed me up, all of my symptoms have been flooding back.

I've tried to recover with a mix of L-Arginine, Acidophilus and another probiotic. I've also just added dried Goji Berries. It's been 5 days since I stopped the Garlic pills and still things aren't back to normal so I'm left questioning whether the arginine and probiotics are as good I thought they were.

I've ordered some L-Taurine powder based on b_jim's experience and will be trying it in the next few days. L-Taurine sounds like it could be the solution to my issues because of these reasons:

1) Taurine is a co-factor for Magnesium and Calcium. I currently react badly to Magnesium, it worsens all of my symptoms so perhaps Magnesium supplementation is depleting what little Taurine I have available. I also react badly to Calcium supplements.

2) Taurine is the main amino acid in the eye, it is also an antioxidant that protects the eye from damage. My most severe symptoms affect my eyes; I have dry eyes, lots of eye floaters, sometimes a feeling like my eyes are swollen and going to explode, seeing flashes of light and intermittent blurry vision particularly when I eat green vegetables like spinach.

3) Taurine has been used to treat tinnitus. Tinnitus is another of my symptoms, I have high-pitched tonal tinnitus in my right ear and sometimes the pulsatile, heartbeat tinnitus in my left ear.

4) Taurine seems to be good for organs like the kidneys, liver & bones. I believe I have issues with all of these, I can't take most supplements without getting kidney pain. My blood tests for bone health are also abnormal.

5) Taurine has been shown to increase Testosterone. This is something I will be able to measure with ease since my Sex Hormone Binding Globulin (SHBG) levels are abnormally high indicating some issue with Testosterone. Providing I tolerate Taurine, I'll be retaking the SHBG test.

6) Taurine seems to be good for muscles, it removes waste products that cause burning, fatigue and other issues. I have some burning sensation in my muscles and twitching, I also get a strange underarm body odour and my urine is very bubbly like I'm expelling something abnormal.

Here's a link to b-jim's original thread for anyone else interested in L-Taurine:

https://poiscenter.com/forums/index.php?topic=1430.0

[Muon]

Flares are also seen in autoinflammatory syndromes.

[Muon]

I have some burning sensation in my muscles and twitching, I also get a strange underarm body odour and my urine is very bubbly like I'm expelling something abnormal.

I always get the impression that something is being dumped into my body and that some kind of clearance rate isn't high enough at that moment to get rid of this concentration, especially when the POIS reaction tones down it feels like my body is covered in something. (this is also something that I experience due to hot weather conditions without POIS trigger)

My interpretation is that POIS ignites an autoinflammatory reaction. Products of this reaction are being dumped into my body and when the autoinflammation diminishes the products are still there lagging behind with the clearance process. Since I also get an oily skin I suspect this might be lipid generation in general as a result of this inflammation. Yes sometimes my urine is bubbly as well.

This is a reason why I want to test for molecules like Lp-PLA2 and other lipid/enzyme products.

I also wonder what your interferon gamma level might be.

And about food reactions, I think it might have to do with an error in our mucosal immune system (perhaps POIS as well).

[Simon66]

Garlic contains a high concentration of FODMAPS by the way. I have been tested for a systemic Candida routine (by world leading doctors) but there is no evidence of systemic defects (this doesn't rule out an intestinal fungal overgrowth which is impossible to detect). The cultures taken are very prone to contamination. I also did a PSA test which was normal.

During my desenz I had moments short after subcutane injections where I felt completely normally. My oral mucous mebrane developed fully, muscles were stronger and I once ate something during this state which I could not tolerate normally and had zero reactions. This state is short-lived and could not be maintained. Sperm is a soup of immune modulators, it's unknown what mechanism is involved here.

I had severe eye pain in the past but I'm in a better state now as far as eye pain is concerned. If it was candida wouldn't it have progressed by now? Every local fungal infection I've had (skin, mouth) progressed without intervention.

I personally think it would be easier to individually test all of the amino acids that deal with detoxification and see which one helps rather than spend loads of money on tests. L-Arginine detoxes ammonia and so far I've found that Arginine improves my gut transit and my sleep. I've also written previously in this thread about an Arginase enzyme that is shared by both the digestive system and the reproductive system so that could be a cause of POIS. L-Arginine apparently is better taken just before bed because it boosts growth hormone and improves sleep. I'm also testing L-Taurine which supposedly has similar benefits.

The food reactions had improved significantly before I took the Garlic and now I seem to have lost some progress. I will eventually find out which of the following gave me the improvement or maybe it was a combination:

Probiotics (BioGaia, BB12, Lindens Acidophilus, Rhamnosus GG)
L-Arginine
Colostrum LD
Goji Berries
Multivitamin
Cheese
Lactose-Free Whole Cow's Milk

[Simon66]

I know from previous tests that Lysine and Arginine seem to help me. I found a research article that suggests I could be dealing with a mitochondrial disorder, chronic fatigue has been one of my symptoms:

Abstract
Mitochondria are important subcellular organelles involved in the energy production that are susceptible to oxidative stress. Acute myocardial infarction has been shown to correlate with an increase in oxidative stress. The protective effect of L-arginine and L-lysine on mitochondrial enzymes, mitochondrial lipid peroxidation, Ca2+ content, enzymes of respiratory chain and ATP production was examined during isoproterenol induced myocardial infarction. Rats administered isoproterenol (150 mg kg-1 daily, i.p.) for two days showed a significant increase in mitochondrial lipid peroxidation and Ca2+ content while the activities of the cardiac marker enzymes, mitochondrial tricarboxylic acid cycle enzymes, enzymes of respiratory chain and ATP production were decreased. Prior oral treatment of L-arginine (250 mg kg?1 daily) along with L-lysine (5 mg kg?1 daily) in combination for 5 days significantly (p < 0.05) prevented these alterations and restored the mitochondrial function at near normal state. These results confirm the combined efficacy of L-arginine and L-lysine in alleviating isoproterenol induced mitochondrial damage.

https://www.sciencedirect.com/science/article/pii/S0271531703002343

[demografx]

I always get the impression that something is being dumped into my body...

Same here.

[Iwillbeatthis]

When you say you've had success with anti fungals which anti fungals are you talking about? I seriously think a certain type fungus are part of the cause of my health problems

[Simon66]

I haven't had any major success, something seems to have given me improvements but I'm still trying to pin it down. I do think my issues are caused by a bacterial or fungal overgrowth.

I am going to take a break from writing on this forum until I can provide you guys with some useful information.

[Iwillbeatthis]

Simon I went and bought l-arginine colostrum and super enzymes as I do trust your analysis and instincts for which treatments you try for yourself. I have been saying for a long time that I think all my problems are due to some type of fungus. With the combo of  l-arginine taurine colostrum and super enzymes I feel much more clear headed and confident, clear spoken and not imbalanced, I'm pretty sure its mainly down to the colostrum. I then thought if I'm feeling like this why not try some Os and my orgasms were much stronger and way more pleasurable than they usually are. I had 4 Os which would usually cause me to be messed up for at least a few days but this time I've recovered in less than 24 hours. Before then I haven't had any os or nocturnal emissions for over a month and my sex drive has been non existent, I guess not such a bad thing when you have POIS. I have been getting weird sensations in the prostate since taking this but maybe  this could be something that is being healed.

The only thing that worries me about colostrum is that I have seen some studies saying it increases the PSA antibody fast which rapidly increases the rate of prostate cancer progressing and I think it can also initiate it. It also increases the IGF1 growth hormone which has a direct link to many cancers. Its annoying because I think this treatment can help me a lot but I don't want endanger my health long term because I didn't consider the risks of the supplement. Please let me know what you think about this. I have alpha blockers for the prostate which I was prescribed years ago but I never tried ,I wonder if this could have any similar effect to the colostrum?
Watch this video from a prostate doctor.
https://www.youtube.com/watch?v=sv637SA5c6o&t=580s


I have also stopped eating vegetables and started using gluten free products instead of just eliminating gluten and from this I have felt much better. When I was in keto without any gluten or carbs I would feel spacey but when I have gluten free products I feel more human and normal.

[Simon66]

The specific colostrum I use is Sovereign Labs Colostrum LD (vanilla flavour), I don't trust any of the other brands.

I have had the big improvements like you've described but they are only temporary for me. I need to experiment more and return to this forum with a completed protocol.

I haven't read about the risks of taking colostrum. Please take it at your own risk, unfortunately I can't help you make this decision.

[Simon66]

Also, if you decide to stop the colostrum I don't think it's a big deal. I have found improvements from several different supplements, there's always something else to try.

As an example, the colostrum may be boosting your immune system to kill a fungal overgrowth but you might find garlic does the same thing or maybe taking a certain probiotic does this as well. I do think there is more than one way to do this.

[Simon66]

Anyone interested in Candida Albicans as a cause of POIS might be interested in the following research article. There's a lot of information in there, it describes POIS symptoms including brain fog, sinus issues, body aching, inability to expel toxins.

Molybdenum is a substance that can be used to expel the Candida toxins.

http://www.arthritistrust.org/wp-content/uploads/2013/03/Molybdenum-for-Candida-albicans-Patients.pdf


Edit

Here's another interesting link about one doctor's experience self-treating candida with molybdenum:

http://www.mall-net.com/cooter/moly.html