Author Topic: Women with Post Orgasmic Illness Syndrome  (Read 12668 times)

Muon

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #30 on: December 02, 2019, 02:36:07 PM »
The fever could be caused by an abnormal response within the HPA-axis.

https://en.wikipedia.org/wiki/Fever#Pathophysiology

IronFeather

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #31 on: December 08, 2019, 04:43:31 PM »
Hi IronFeather,

1) You are talking about your teenage years, what's your age?

2) Symptoms started 1 year after your first period, was this the first time you masturbated?

3) Do you produce more natural lubricant when you orgasm?

4) How much time, roughly speaking, is there between the moment you start masturbating and reaching orgasm? There are people here with (lifelong) premature ejaculation.

5) Did you experience other symptoms before 'POIS' symptoms made their appearance?

6) What was the antibiotic you were using?

7) Did they measure your vitamin D, lactoferrin, interferons, NK, T and B cells?

8.) If you feel like sharing your lab results you can do so here: https://poiscenter.com/forums/index.php?topic=2684.0

Hi Muon, sorry that it took me so long to reply to this.

1) I'm 23 now, but I'll be 24 at the end of December. I've had POIS symptoms ever since I was around 12 or 13 years old, I can't remember exactly but I know it was around that age.

2) No, I was very young when I first masturbated, less than 3 years old. I used to do it very often as a kid, probably daily, unless I was sick. I used to be sick pretty often too, which I later found out was caused by a food intolerance (a very bad one, almost an allergy) to soy.

3) I can't be 100% sure, but I think I don't. Since arousal doesn't seem to cause POIS symptoms for me (yet, at least), I've been edging a lot lately but avoiding orgasm altogether, and I haven't noticed any decrease in the amount of lubricant that I produce.

4) If I were a man, I'd suffer from premature ejaculation for sure. I can orgasm in one minute easily, and it never takes me longer than two unless I'm playing/waiting on purpose.

5) Hmm, I don't think so. The only health problems I've had in my life are my soy allergy and an extreme sensitivity to cold (I never catch a cold or the flu from somebody else, but going outside in winter without four or five layers of clothes mean I'm going to get sick, 100% guaranteed). I also have very bad acne, I've had it since my first period, and I believe it's POIS-related because it gets noticeably worse during an episode.

6) I was prescribed cefixime. I took it for five days before it caused me to stop absorbing food adequately, I was going to the bathroom three-four times a day, so I had to stop taking it. But apparently it was enough, the symptoms had already lowered in intensity and I slowly improved by myself until the episode was over.

7) They did measure my vitamin D, which is always very low, below the critical levels. I'm taking vitamin D in drops daily but I don't seem to improve... I'm not sure about the other parameters, I'm going to see if I can find the results and check!

8.) Yes, of course, I'll post them as soon as I find them. They're in Spanish but medical terms tend to be very similar anyway, and if I can find the time I'll translate them too.

The vagus nerve idea seems interesting to me, because before I had even heard about POIS, I realized that one of my symptoms was a strange feeling of something being wrong around the center of my abdomen (the middle of the diaphragm, more or less), and if pressed that area my other symptoms got much worse. I told a doctor about this and, after some thinking, he told me that the only thing that occurred to him was something being wrong with my vagus nerve. And the only time that I got full POIS symptoms completely unrelated to masturbation, it happened after laying in bed face down reading a book, pressing that exact same spot against the bed. But what could possibly be wrong with the vagus nerve?


« Last Edit: December 08, 2019, 04:46:30 PM by IronFeather »
25-year-old Spanish woman with POIS symptoms for the last 12 years.
Suffering from exercise intolerance since April 2020.

demografx

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #32 on: December 08, 2019, 10:43:29 PM »

The vagus nerve idea seems interesting to me, because before I had even heard about POIS, I realized that one of my symptoms was a strange feeling of something being wrong around the center of my abdomen (the middle of the diaphragm, more or less), and if pressed that area my other symptoms got much worse. I told a doctor about this and, after some thinking, he told me that the only thing that occurred to him was something being wrong with my vagus nerve. And the only time that I got full POIS symptoms completely unrelated to masturbation, it happened after laying in bed face down reading a book, pressing that exact same spot against the bed. But what could possibly be wrong with the vagus nerve?


IronFeather, this forum committed heavily at one time to researching vagal dystonia as a possible POIS culprit. Some of us continue experimenting with tVNS devices as a possible POIS treatment:
https://poiscenter.com/forums/index.php?topic=2969.0
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Hopeoneday

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #33 on: December 09, 2019, 12:55:48 PM »


5) Hmm, I don't think so. The only health problems I've had in my life are my soy allergy and an extreme sensitivity to cold (I never catch a cold or the flu from somebody else, but going outside in winter without four or five layers of clothes mean I'm going to get sick, 100% guaranteed). I also have very bad acne, I've had it since my first period, and I believe it's POIS-related because it gets noticeably worse during an episode.


The vagus nerve idea seems interesting to me, because before I had even heard about POIS, I realized that one of my symptoms was a strange feeling of something being wrong around the center of my abdomen (the middle of the diaphragm, more or less), and if pressed that area my other symptoms got much worse. I told a doctor about this and, after some thinking, he told me that the only thing that occurred to him was something being wrong with my vagus nerve. And the only time that I got full POIS symptoms completely unrelated to masturbation, it happened after laying in bed face down reading a book, pressing that exact same spot against the bed. But what could possibly be wrong with the vagus nerve?
Hi IronFeather- 5)-match with me complitly the same(severe acne in that age, cold intoleraces,colds after that...
Vagus nerve could be infected (by "my theory"), or toxic , again by "my theory" and linked to gut and imunity.
I will write about this soon.

Sometimes only air small of bloat on that erea, induce me to hawe heart palpilations, in pois badly.
« Last Edit: December 09, 2019, 04:12:48 PM by Hopeoneday »
Dr-pois.

Muon

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #34 on: December 13, 2019, 06:46:05 PM »
9) Did you do a test for soy allergy to determine it's a true allergy? And was this soy 'allergy' present before your first POIS symptoms emerged?

10) Do you have any intravaginal sensitivities?

11) Have you ever tried NSAIDs? https://en.wikipedia.org/wiki/Nonsteroidal_anti-inflammatory_drug

12) Do the sickness symptoms from cold exposure have any overlap with POIS symptoms?

13) Do you have any problems with heat, like hot weather?

14) Do you experience any autonomic related symptoms/dysfunction (see picture below)?

15) Do you have any relatives with health problems? If so what kind of health problems?

16) Are you susceptible to stress? And once you are stressed is it difficult to reverse this?



https://en.wikipedia.org/wiki/Dysautonomia
« Last Edit: December 13, 2019, 07:06:42 PM by Muon »

Muon

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #35 on: December 25, 2019, 11:51:22 AM »
About what Nas asked me, my libido is always insanely high, as embarrassing as it is to admit it, and it doesn't decrease much after orgasm.

''Finally, there is the mystery of the presence of mast cells in neuroendocrine organs, such as the pineal, hypothalamus, pituitary, thyroid and the uterus [3], where the pathophysiologic function of the mast cells remains unknown. These findings may possibly explain our observation that many females with MCMD report increased libido and orgasms.''

Recent advances in our understanding of mast cell activation - or should it be mast cell mediator disorders?

I wonder if her fever could be explained by mast cell activation in the hypothalamus.
« Last Edit: February 16, 2020, 07:36:00 PM by Muon »

IronFeather

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #36 on: January 03, 2020, 01:23:59 PM »
9) Did you do a test for soy allergy to determine it's a true allergy? And was this soy 'allergy' present before your first POIS symptoms emerged?

10) Do you have any intravaginal sensitivities?

11) Have you ever tried NSAIDs? https://en.wikipedia.org/wiki/Nonsteroidal_anti-inflammatory_drug

12) Do the sickness symptoms from cold exposure have any overlap with POIS symptoms?

13) Do you have any problems with heat, like hot weather?

14) Do you experience any autonomic related symptoms/dysfunction (see picture below)?

15) Do you have any relatives with health problems? If so what kind of health problems?

16) Are you susceptible to stress? And once you are stressed is it difficult to reverse this?

I'm sorry that I'm taking so long to reply, I'm about to start college final exams and it's taking a toll on my free time, that was almost non-existent anyway. I'll try to come back here more often from now on.

9) I haven't done a soy allergy test, so I can't be sure if it's a true allergy or not, but I believe it isn't. I have been eating soy consistently since I was a kid, because a lot of foods that I love have soy as an ingredient or even the main ingredient (tamari sauce, miso, sushi), and never had any intense reactions except for stomach problems, and it took me years to realize that soy was the cause. It got worse when (around 10 years old) I incorporated new foods with soy into my diet and my digestive system couldn't take it anymore: I spent 4 months with colitis and lost half of my weight until thankfully my mother deduced that soy was the culprit. So I believe that, if it was a true allergy, I'd have had a more intense reaction. And yes, I've never tolerated soy well, and I've had that problem for as long as I can remember.

10) Not at all, at least not that I know.

11) No, I haven't, I try to avoid taking medications as much as possible. The only medications I've taken in my life are paracetamol and a couple of antibiotics, always because of the flu or very bad POIS episodes when I needed to manage the symptoms.

12) No, not at all. The only effect that cold has on me is that, well, I get a cold or the flu pretty easily, especially if my feet get cold. Now that my POIS symptoms are getting worse, I also get a very sore throat with it, but it's a completely different kind of sore compared to when I'm sick from a cold. It doesn't feel like an infection, it just hurts, if that makes sense.

13) Not at all, I love hot weather.

14) That's an interesting question. I've definitely had stomach problems related to POIS, stomachaches and gas that can't be explained by any change in my diet and that disappear when POIS symptoms go away. And also an elevated heart rate, but maybe that's because of the fever?

15) My two grandmothers died from breast cancer, and one of my grandfathers died of prostate cancer, but apart from that, the only health problems I can think of in my family are the endless digestive problems of my mother. She's been diagnosed with irritable bowel syndrome and lactose intolerance, but her troubles only appeared after the emotional turmoil of her relationship with my physically abusive father, so that might explain her issues.

16) No, not at all. I live a very stressful life as a student, always trying to get perfect grades and studying two degrees at the same time (I'm an extreme perfectionist), and it hasn't given me any problems so far, I'm used to stress and have always worked well under pressure.

If you have any other questions, Muon, feel free to ask whatever, I'll try to reply as soon as possible! :)
25-year-old Spanish woman with POIS symptoms for the last 12 years.
Suffering from exercise intolerance since April 2020.

Muon

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #37 on: January 13, 2020, 12:41:50 PM »
16) No, not at all. I live a very stressful life as a student, always trying to get perfect grades and studying two degrees at the same time (I'm an extreme perfectionist), and it hasn't given me any problems so far, I'm used to stress and have always worked well under pressure.

You may be completely wrong about your statement highlighted in bold.

Fever is also a symptom of colitis. It may be possible that you are triggering colitis by sexual activity. Mucosa is dense in mast cells. If you are triggering mast cells it could lead to inflamed mucosa, in your case colitis. I'm not sure what part of the GI tract absorbs vit D, I wonder whether the colonic inflammation inhibits Vit D absorption. Iron deficiency could have made your Vit D low: https://vitamindwiki.com/Iron+deficiency+is+a+cause+of+Vitamin+D+deficiency

My two cents: There is probably some interaction between: Mast cells, mucosa, colitis, sexual activity, iron, vitamin D, stress. I bet the sore throat is probably mucosal mast cell activation as well. Your first intestinal mucosal mast cell trigger was soy, the second trigger later in life might be sexual related, which could synergize with stress.

Often seen, rarely recognized: mast cell activation disease - a guide to diagnosis and therapeutic options

Table 1:  Cold intolerance,  Mood disturbances (e.g., anger, depression (13%)), inflammatory/irritable bowel syndrome (colitis=IBD), selective vitamin and/or other micronutrient deficiencies, weight change, increased susceptibility to infection, Soy: Types I, II, III, and IV hypersensitivity reactions (e.g., allergy, delayed-type hypersensitivity, etc.).
« Last Edit: January 17, 2020, 05:42:27 PM by Muon »

Timtim

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #38 on: January 21, 2020, 05:52:54 AM »
Hi everyone. I am a female poiser.
I am 27 and I had the symptoms since I was 10 or something.
I used to overmasturbate. And I think my pois is because of excessive masturbation
 I started masturbating at the age of 10 or so I guess, however this habit was not an ongoing one. I mean it was on and off. at the age of 19 I stopped masturbating and having sex and I did not have NE and that age. After 1 year of not having orgasm my symptoms have been reduced, but did not disappear. My face used to get very ugly and my stress level was super high. Now I still get ugly after orgasm but not as much as it used to get, and I still have all symptoms but in a lighter level compared to the past. But it is still VERY annoying. I decided to stop having orgasm for a couple of years but that seems impossible because of NEs. Every 6 day one NE!
I am sure my pois is because of over masturbation
My question is if any of you has the same problem? Did you over masturbate?
Do you think excessive masturbation or masturbating at early age (before puberty) caused your pois, too?
My English is not very good, sorry about it.

demografx

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #39 on: January 21, 2020, 07:52:12 AM »
Timtim, I do think that over-engagement is a possible cause, but I also know that many people here disagree.
« Last Edit: January 21, 2020, 07:53:46 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Clues

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #40 on: January 21, 2020, 07:53:20 AM »
Hi Timtim. :) Respectfully, even if there were a correlation between over-masturbation and POIS, there may not be a causal relationship. Also, to even define over-masturbation you'd have to have some solid statistics on how much people masturbate. Not saying you're definitely wrong, just saying I'd be careful not to assume you caused it yourself and potentially suffer guilt on top of everything else. :)

My personal guess at how I got POIS is over-prescription of antibiotics (like Tetracycline). Not scientific, just my layman's guess based on timing and other forum users' experiences. I'm male btw.

Timtim

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #41 on: January 21, 2020, 01:29:32 PM »
Hi Timtim. :) Respectfully, even if there were a correlation between over-masturbation and POIS, there may not be a causal relationship. Also, to even define over-masturbation you'd have to have some solid statistics on how much people masturbate. Not saying you're definitely wrong, just saying I'd be careful not to assume you caused it yourself and potentially suffer guilt on top of everything else. :)

My personal guess at how I got POIS is over-prescription of antibiotics (like Tetracycline). Not scientific, just my layman's guess based on timing and other forum users' experiences. I'm male btw.
That is interesting. When I was a child I was prescribed 20 days of penicillin injection, is it considered over-prescription?
« Last Edit: January 21, 2020, 04:50:34 PM by Timtim »
My English is not very good, sorry about it.

Clues

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #42 on: January 22, 2020, 03:39:45 AM »
Timtim, I'm not sure, depends on what it was prescribed for I guess. Sounds like a lot though. These days there is increasing interest in the link between the human microbiome and diseases/conditions that were thought to be unrelated before. Good primer on it here: https://www.theguardian.com/news/2018/mar/26/the-human-microbiome-why-our-microbes-could-be-key-to-our-health

Muon

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #43 on: January 22, 2020, 11:28:51 AM »
...my stress level was super high.
Stress again...

You talk about excessive masturbation or overmasturbating. This doesn't tell me anything if you don't mention the frequency.

What's your educational background if I may ask?

hurray

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Re: Women with Post Orgasmic Illness Syndrome
« Reply #44 on: January 22, 2020, 04:59:39 PM »
...my stress level was super high.
Stress again...

You talk about excessive masturbation or overmasturbating. This doesn't tell me anything if you don't mention the frequency.

What's your educational background if I may ask?

I'm not sure that these are appropriate questions to be asking a new poster, especially given that she hasn't engaged directly with you.

Many people who come to this forum have only just found out about POIS, and they are seeking reassurance and guidance.
« Last Edit: January 22, 2020, 05:03:55 PM by hurray »