So one of the biggest mysteries about POIS that I just simply cannot decipher, is the type of immune response that is suggested to cause the symptoms. On one hand, Waldinger tested positive for semen prick tests, but is this an indication of auto-immune disease? In that I question, whether normal people also can test positive for semen prick test without having POIS? Then I ask about the type of immune response in POIS, if it is MCAS related, then why does usual MCAS treatment which comprises of anti-histamine treatment not work for me? When I try to think about possible reasons I can not find any other explanation to MCAS. Yet when I ask MCAS sufferers who suffer from Neuropsychiatric symptoms about what they take as remedy they say that usual MCAS treatment gave them back their brain, yet it clearly fails in my case. In fact I question if there was an immune response at all?
I know that Muon always suggests doing tests but where have tests lead us so far? We need a better theoretical frame to base our tests on. Currently I find the Mast Cell theory to be the most testable of the other theories. But I find that the lack of effect the MCAS treatment regiment had on me is starting to give me doubts. This illness is nothing less than a curse, one that is more seen in the world of the metaphysical. Sigh.
