Author Topic: What am I doing wrong?  (Read 1458 times)

The One

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What am I doing wrong?
« on: April 14, 2021, 12:21:58 PM »
Hey everyone,

I've nearly given up on trying to treat my POIS. I've tried almost every treatment on this forum with no success.

Here's what I've tried so far:

I've given most of these trials at least a month. But none of them treated my symptoms which are:

- Fatigue (Exhaustion)
- Cognitive Issues (Concentration issues, memory issues, anxiety)
- Flu-Like Symptoms (Sneezing, Itchy Eyes, Itchy Nose, Headache, Warmth)
- Sweating (Hands, Feet, Body)
- Depressed Mood (Angry, Sad, Lonely, Irritability)
- Heart (Palpitations)
- Dry Mouth
- Lower Back Pain

(I suffer from all 7 POIS clusters.)

My symptoms show up within 30 minutes and last between 1-5 days. It seems the only thing that's worked so far is abstinence.

Is there any other treatment worth trying? Or is abstinence the only solution?

Thanks,
The One

PS - I've suffered from POIS for over 10 years ever since my first O.

Nas

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Re: What am I doing wrong?
« Reply #1 on: April 14, 2021, 03:02:51 PM »
Pretty much the same as your case except I only have psychological symptoms. I've tried everything and nothing works. 
I am still looking to try other things. For example I want to try Bupropion, someone recently said that it helped and he connected his POIS to potential norepinephrine deficiency.
I also want to take a DNA test to see what mutations I have that could have some connections to POIS.
We are still in a desperate situation but the hunt is not over.

berlin1984

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Re: What am I doing wrong?
« Reply #2 on: April 14, 2021, 03:26:40 PM »
Welcome to the real world, Neo.

My reply to a similar post:

Have you ever visited a doctor? :) Just for a general checkup, without mentioning POIS and NOT to get antidepressants.

Yes, stress is a killer for me too.

Other questions:
1) How is your sleep?
2) What is your diet exactly? What do you eat? Are you vegan/vegetarian or anything else that could lead to deficiences?
2b) Do you take in enough salt?
3b) Do you drink enough? I can recommend alcohol free wheat beer with lemonade.. if you're without access to that, you might want to try something like Gatorade..
3) Do you have dental problems?
4) Have you tried breathing exercises?
5) Have you tried taking walks in nature? (I feel bad if I don't take a walk daily..)
6) Have you looked into taking a multivtamin? You can do this ASAP. For physical weakness, additionally I have good experience with ALCAR and Q10.
8) 3 days before re-starting work is a bit little, but if I was you I'd try Ashwagandha Extract and Rosea Rhodiola. Both can help to stabilize mood, anxiety, testosterone, stress resisence, ...


PS: I cannot abstain, if I abstain for too many days (like a week) my brain and mind

In addition, I have very good experience with a kind of licorice candy and this supplement with saffron, fenugreek and other good stuff.
https://poiscenter.com/forums/index.php?topic=3011.msg37974#msg37974 <- Licorice candy
https://www.amazon.de/NATURTREU%C2%AE-Maca-Kapseln-hochdosiert-3000/dp/B07L6NTFJK <- the supplement

Do you consume coffee?
Black strong coffee is really help so so much on the day after for part of the symptoms I have.


Prospero

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Re: What am I doing wrong?
« Reply #3 on: April 14, 2021, 03:44:57 PM »
If I were you, I would try to do as many blood tests as possible. It is perfectly possible that POIS arises from different conditions specific to each of us, so trying to find out which health parameters are abnormal in your own case may be a good beginning. Also, try to examine what has happened in your life so far (illnesses, drugs taken, potential traumatic events) and what characterizes you (psychological tendencies, physical specificities, allergies, health problems in your family, etc.). It might give you or your doctor a clue about where to search.

demografx

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Re: What am I doing wrong?
« Reply #4 on: April 14, 2021, 04:13:47 PM »

I want to try Bupropion, someone recently said that it helped and he connected his POIS to potential norepinephrine deficiency.


I’m just one guy, but I had adverse results. Lexapro has been working for me for many years. Just an FYI.
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

berlin1984

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Re: What am I doing wrong?
« Reply #5 on: April 15, 2021, 02:23:43 AM »
Here's what I've tried so far:

Another thing I've noticed in the forum is that people might be looking for single causes or single cures (supplement or lifestyle or medication).

But often what is needed might be a combination of chronic things and acute things.
An example: demografx is taking TRT and an antidepressant (Lexapro) in combination and then a specific antihistamine to manage (not cure) his symptoms.


demografx

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Re: What am I doing wrong?
« Reply #6 on: April 15, 2021, 03:46:42 AM »
berlin1984, thank you for differentiating between the management of symptoms vs a cure.
« Last Edit: April 15, 2021, 06:40:00 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

The One

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Re: What am I doing wrong?
« Reply #7 on: April 15, 2021, 08:46:39 AM »
Thanks for differentiating that for me.

I figured I might need a 'stack' to get this to work. The problem is the individual components haven't really worked.

What do you guys think of Nanna1's immune incompetence stack? Or is this entire POIS thing psychosomatic?

Gino

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Re: What am I doing wrong?
« Reply #8 on: April 18, 2021, 12:34:41 AM »
Hey everyone,

I've nearly given up on trying to treat my POIS. I've tried almost every treatment on this forum with no success.

Here's what I've tried so far:
... list

Is there any other treatment worth trying? Or is abstinence the only solution?

Thanks,
The One


Hi The One

Here's what's working for me since early Jan 2021:

https://poiscenter.com/forums/index.php?topic=3746.0

The One

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Re: What am I doing wrong?
« Reply #9 on: April 20, 2021, 04:10:09 PM »
Hey everyone,

I've nearly given up on trying to treat my POIS. I've tried almost every treatment on this forum with no success.

Here's what I've tried so far:
... list

Is there any other treatment worth trying? Or is abstinence the only solution?

Thanks,
The One


Hi The One

Here's what's working for me since early Jan 2021:

https://poiscenter.com/forums/index.php?topic=3746.0
Thanks Gino for the recommendation! I'm giving it a try.

Here's what I'm going to take:
-500 mg Niacin (2-6 hrs before O): https://www.amazon.com/NOW-Niacin-500-100-Capsules/dp/B004LVW8TU
-Matcha Tea (Immediately to 30 mins before O): https://www.amazon.com/Ch%C3%A9rie-Sweet-Heart-Matcha-Powder/dp/B07P6454Z1/
-Vitamin C + Echinacea: https://www.amazon.com/Solaray-Echinacea-Vitamin-Capsules-Count/dp/B000I4DIU2/

Do these check out? Also, do you have a better Matcha recommendation? I'm having a hard time finding yours.

Thanks for stopping by :)
« Last Edit: April 20, 2021, 04:14:02 PM by The One »

Gino

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Re: What am I doing wrong?
« Reply #10 on: April 28, 2021, 02:45:59 AM »
Hi The One.

I've replied to your post on my topic. https://poiscenter.com/forums/index.php?topic=3746.0

Good luck and please do report how it goes for you.

The One

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Re: What am I doing wrong?
« Reply #11 on: April 28, 2021, 12:21:03 PM »
Hi The One.

I've replied to your post on my topic. https://poiscenter.com/forums/index.php?topic=3746.0

Good luck and please do report how it goes for you.

Just in case you didn't see my reply in my thread.

I'm planning on replicating your stack.

Here's what I'm thinking of taking:
-500 mg Niacin (2-6 hrs before O): https://www.amazon.com/NOW-Niacin-500-100-Capsules/dp/B004LVW8TU
-Matcha Tea (Immediately to 30 mins before O): https://www.amazon.com/Ch%C3%A9rie-Sweet-Heart-Matcha-Powder/dp/B07P6454Z1/
-Vitamin C + Echinacea (Daily): https://www.amazon.com/Solaray-Echinacea-Vitamin-Capsules-Count/dp/B000I4DIU2/

Do these check out? Also, do you have a better Matcha recommendation? I'm having a hard time finding yours.

Hi The One.

Overall it looks like the products you listed are very similar to mine. Your timing method also seems similar (B3 taken 2-6 hours beforehand and matcha taken just beforehand)

If you prefer I can buy my exact local products and mail them to you (PM me).

- My notes of potential differences:
 1. My B3 are in hard tablet form, rather than soft capsule form. Not sure if this matters?
 2. My B3 ingredient is listed as "niacin, nicotinamide". I'm not sure if this is different to just Niacin?
   (link: https://www.chemistwarehouse.com.au/buy/21113/nature-s-own-vitamin-b3-500mg---vitamin-b---60-tablets)

Further points:
- In the 2-6 hour period beforehand I only ate a light meal and did not drink alcohol. I'm yet to test if that matters.
- Matcha powder is very potent. I only took 1/3 teaspoon to a small cup. I drank all the powder that falls to the bottom of the cup.

Results I get:
- I am very clear minded even after O. This is a welcome but strange feeling for someone who suffers POIS.
- I can still sleep well with this level of tea (whereas a late night coffee leaves me awake and jittery)
- I do not experience any mind or body symptoms on that day/night or in the following days.

Hope this works well for you!


Hey Gino,

Thanks for clearing this up. I've went ahead and tried your experiment.

I took niacin and waited 3 hours (I flushed) and took Matcha 25 minutes before O. Then, I had an O.

The result was the same symptoms.

It could be the niacin I used, but I doubt there's a difference between ours.

I'm really glad it's working for you. Keep on doing it!

Anyone have any other recommendations?

Muon

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Re: What am I doing wrong?
« Reply #12 on: April 28, 2021, 12:31:43 PM »
Nicotinic acid (niacin) is not the same as nicotinamide (niacinamide), both are called Vitamin B3. I would try it again with nicotinamide.

The One

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Re: What am I doing wrong?
« Reply #13 on: April 29, 2021, 03:47:54 PM »
Nicotinic acid (niacin) is not the same as nicotinamide (niacinamide), both are called Vitamin B3. I would try it again with nicotinamide.

Alright, I'll give the other form a try.

This is the product I'm going to buy: https://www.amazon.com/Natures-Way-Niacinamide-500mg-Packaging/dp/B000I4AIUK/.

Look good?

Gino

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Re: What am I doing wrong?
« Reply #14 on: April 30, 2021, 11:31:41 PM »
Nicotinic acid (niacin) is not the same as nicotinamide (niacinamide), both are called Vitamin B3. I would try it again with nicotinamide.

Alright, I'll give the other form a try.

This is the product I'm going to buy: https://www.amazon.com/Natures-Way-Niacinamide-500mg-Packaging/dp/B000I4AIUK/.

Look good?

Hi The One.

Best to ask your pharmacist how similar my one is to theirs. Mine is a 500mg Niacinamide (also called Nicotinamide) solid white tablet and doesn't make me flush.

Closest i could see on Amazon is this 250mg tablet: https://www.amazon.com/Vitacost-Niacinamide-Vitamin-B-3-Tablets/dp/B006GJHJ4Y/ref=mp_s_a_1_3

Read up on the difference between Niacin (flush) and Niacinamide (also called Nicotinamide) (non flush). Importantly do not cut or crush the tablet:

https://www.webmd.com/drugs/2/drug-6926/niacinamide-oral/details

I hope you can fully recover before the next attempt.




The One

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Re: What am I doing wrong?
« Reply #15 on: May 01, 2021, 09:24:18 AM »
Nicotinic acid (niacin) is not the same as nicotinamide (niacinamide), both are called Vitamin B3. I would try it again with nicotinamide.

Alright, I'll give the other form a try.

This is the product I'm going to buy: https://www.amazon.com/Natures-Way-Niacinamide-500mg-Packaging/dp/B000I4AIUK/.

Look good?

Hi The One.

Best to ask your pharmacist how similar my one is to theirs. Mine is a 500mg Niacinamide (also called Nicotinamide) solid white tablet and doesn't make me flush.

Closest i could see on Amazon is this 250mg tablet: https://www.amazon.com/Vitacost-Niacinamide-Vitamin-B-3-Tablets/dp/B006GJHJ4Y/ref=mp_s_a_1_3

Read up on the difference between Niacin (flush) and Niacinamide (also called Nicotinamide) (non flush). Importantly do not cut or crush the tablet:

https://www.webmd.com/drugs/2/drug-6926/niacinamide-oral/details

I hope you can fully recover before the next attempt.




Thanks for clarifying, Gino :)

It turns out I bought the wrong version of niacin. The new one (niacinamide) is the same form as yours.

I'll give this experiment one more try :)