Here :
https://www.sciencedirect.com/science/article/pii/S2050116118300199 (Intralymphatic Immunotherapy With Autologous Semen in a Korean Man With Post-Orgasmic Illness Syndrome)
Interesting this new type of therapy, it would seem more effective. In general, according to an other study (
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352255/), "as few as three low dose intralymphatic allergen administrations are sufficient to effectively alleviate symptoms. Results of recent prospective and controlled trials suggest that this strategy may be an effective form of allergen immunotherapy". Even if in the Korean study, scientists say that "the pathogenesis of POIS cannot be entirely explained by allergies".
It's interesting that they observed levels of IgG3 below the normal in the patient?s serum.
Hormones were abnormal: Testosterone was too low, prolactin was too low (Weird, right? I would have thought the opposite) and estradiol was too high.
Normally, prolactin deficiency is associated with pituitary dysfunction. But following orgasm, prolactin incresease acoording to this study
https://link.springer.com/article/10.1007/s11930-008-0025-6 : "Activation of the hypothalamic pituitary axis associated with orgasmic-like responses results in increased plasma levels of prolactin (but no changes in cerebral spinal fluid levels). The reason for this and the role, if any, of prolactin in orgasm is unclear."
what do you think?
