Before I understood what POIS was or that it even existed, I thought I suffered from something called "post coital dysphoria", also known as post coital tristesse or post coital depression. Much like POIS there's little known about it, and these may even be the exact same thing as POIS.. I wouldn't be surprised.
Anyway, while trying to understand and research what the hell was wrong with me I remember coming across this article in which some doctor kind of found a solution/cure to these issues:
http://www.yourtango.com/20099673/treating-post-coital-depressionIf you read the short and crappy article, you'll see that the doctor used prozac type drugs to "stunt" the orgasm of people suffering, which resulted in no symptoms after sex, however the orgasms were less pleasurable than usual.
I've always had a really bad onset of POIS symptoms right after sex. The biggest sign for me is that immediately after sex I feel a massive disconnect from the woman and desire to get away and be alone. I can't stand being touched after sex. Anyway, a few years ago I recall being pretty drunk as I had sex with this woman and I remember my orgasm being really "lame", as in it didn't amount to very much. It was a very dull orgasm and I couldn't feel much, likely from how much alcohol was in my system. I remember it was one of the very few times if not the only time I can recall not wanting to leave right away. I felt the same as before orgasm.
I'm wondering if there's some truth or connection to this theory of stunting orgasm and severity of symptoms afterwards. I wonder if anyone on the forum has treated themselves with prozac or zoloft. Or if anyone has experienced something similar.