Inflammatory markers that could be used to diagnose POIS ?

[Quantum]

Mr Raba,

in another thread, you have mentioned that your CFS has been diagnosed through special blood tests that are not part of regular blood tests:

CFS is now know to be a severe inflammatory disorder with inflammation of the brain.  Inflammation markers are chronically elevated.
The brain inflammation can not be  detected by current regular patient tests, but has been clearly identified in research papers using advanced technologies not commonly used outside research.  The inflammatory markers in question are not tested in the usual testss doctors ran.  Mine were test at NOVA's center for neuroimmune medicine and they were categorically off and clearly show that there is sever chronic inflammation in many key markers;.

All the brain issues are  for POIS and CFS.  POIS being in my case more severe but shorter.  The flu like symptoms as well.  Fatigue etc.

( this comes from http://poiscenter.com/forums/index.php?topic=341.msg16425#msg16425


I would be very interested to know about what inflammatory markers have been used in those tests for CFS, it could prove useful in future POIS research, if there is truly similarities between POIS and CFS.  Is that CRP ( C-reactive protein), or maybe ESR (but erythrocyte sedimentation rate is not that uncommun as a test) ? 

[Nightingale]

Original paper: http://m.pnas.org/content/113/37/E5472.full

Question and answer with lead author: http://www.openmedicinefoundation.org/2016/08/30/metabolic-features-of-chronic-fatigue-syndrome-q-a-with-robert-naviaux-md/

Pop-sci article for easy understanding: http://www.sciencealert.com/chronic-fatigue-syndrome-is-similar-to-entering-hibernation-study-finds

In depth discussion at big CFS forum: http://forums.phoenixrising.me/index.php?threads/naviaux-et-al-metabolic-features-of-chronic-fatigue-syndrome.46486/

Best,
Tom

[b_jim]

Very interesting post. I'm quite sure my CRP was normal when tested in POis.
I didn't read your experience with Rosemary and Tumeric, Nighingale but it's brilliant if it help to avoid ibuprofen or other med.

i've started to substitute my taurine supplmenent by tumeric supplement (about 500mg of tumeric with pepper)

[certainlypois2]

Very interesting post. I'm quite sure my CRP was normal when tested in POis.
I didn't read your experience with Rosemary and Tumeric, Nighingale but it's brilliant if it help to avoid ibuprofen or other med.

i've started to substitute my taurine supplmenent by tumeric supplement (about 500mg of tumeric with pepper)

Are using turmeric instead of taurine  or are using both together to get benefits from both.

[Quantum]

Original paper: http://m.pnas.org/content/113/37/E5472.full

Question and answer with lead author: http://www.openmedicinefoundation.org/2016/08/30/metabolic-features-of-chronic-fatigue-syndrome-q-a-with-robert-naviaux-md/

Pop-sci article for easy understanding: http://www.sciencealert.com/chronic-fatigue-syndrome-is-similar-to-entering-hibernation-study-finds

In depth discussion at big CFS forum: http://forums.phoenixrising.me/index.php?threads/naviaux-et-al-metabolic-features-of-chronic-fatigue-syndrome.46486/

Best,
Tom

Thanks for the links, Nightingale.


As read in these articles, here are the markers that are decreased in CFS, The decreases in these metabolites correlated with disease severity:

Sphingolipids,
glycosphingolipids,
phospholipids,
purines,
microbiome aromatic amino acid and branch chain amino acid metabolites,
FAD,
lathosterol


It would need a study in itself in order to see of this applies as well to POIS, and if that any treatment that would be discovered for CFS would be useful for POIS.  However, for now, there is still no official treatment for CFS.

[b_jim]

Are using turmeric instead of taurine  or are using both together to get benefits from both.
[/quote]

i taketumeric only to see if it influence my Pois.