Update I have been using histaquel for over two weeks now and haven't seen any difference, for me personally I have doubts now that my issues are mast cell related.
I think Nanna's immune deficiency theory is whats going wrong with me. I have started amitriptyline as of two days ago, I have tried it in the past at a tiny dose (1/4 of 10mg) as advised by my doctor and combined it with piracetam and alpha gpc (I think this is also what caused my severe reactions to showers when i stopped). The trouble was I was still experiencing immune and infectious symptoms back then so I stopped the amitriptyline.
Now I have cleared the infectious symptoms mainly I am trying it again at the full dose of 10mg, as I still have adrenal issues eg: reactions to showers. In a organic acids test it said I had a high HVA/VMA ratio which meant my body was having difficulty converting dopamine into noradrenaline. I have tried co factors for noradrenaline like vitamin c and copper but they aren't strong enough. This also explains why I react badly to bupropion a dopamine antagonist and n acetyl tyrosine.
The test recommends droxidopa - Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine. Unlike norepinephrine, droxidopa is capable of crossing the protective blood–brain barrier. However I am unable to get this in the Uk as its not licensed here or on any online eu pharmacys.