Author Topic: Cabergoline  (Read 4106 times)

Starsky

  • NDL_Group
  • Full Member
  • ***
  • Posts: 237
Cabergoline
« on: June 29, 2012, 04:52:44 AM »
Sex and Cabergoline
By David Jay Brown

Cabergoline is a fairly new pharmaceutical that has enormous potential to aid male stamina. Perhaps the most remarkable aspect of carbergoline is that it has been found to substantially raise a man’s chances of sustaining multiple orgasms during sex. Some men on cabergoline are able to have numerous multiple orgasms in rapid succession.

Cabergoline, which is marketed under the trade name of Dostinex, is used to treat Parkinson's disease, to prevent women producing milk when they want to stop breast feeding, and to lower prolactin levels in patients with a pituitary tumor. It is also sometimes used to help men with sexual dysfunction.

It is cabergoline’s capacity to lower prolactin levels that makes it such a sexual wonder drug for men. Prolactin is a single-chain protein hormone, closely related to growth hormone, that stimulates the secretion of milk of women. The hormone also has the effect of reducing a man’s desire for more sex by preventing new erections. Cabergoline has been found to to minimize the effects of the hormone prolactin, which is produced by men at the point of orgasm. As a result, some subjects who tried the drug found that they were able to have multiple orgasms in rapid succession.

In one study, 60 subjects, all healthy males, between the ages of 22 and 31, normally needed a break of 19 minutes between lovemaking sessions. However, after taking Cabergoline, they were able to have several orgasms within a few minutes. Medical psychologist Manfred Schedlowski, who was involved in the trials at Essen in Germany, said the drug raised the libido to enable the male to orgasm again more quickly.


Schedlowski said, "We saw that prolactin rises after orgasm and then thought maybe prolactin is a negative feedback system. Subjects who took this drug had decreased prolactin levels, and reported their orgasm was better and there was a shorter refractory period. We interviewed these subjects and found they were able to have multiple orgasms in very rapid succession. This is sitting very nicely with our hypothesis that orgasms and sexual drive are steered by prolactin and dopamine in the brain."

Cabergoline was reported to have no side effects on men during the tests, according to a paper that was published in the International Journal of Impotence Research. However, there may be a drawback. There’s evidence that the release of prolactin in the brain, which surges during orgasm, promotes the growth of new neurons in the brain--a process called neurogenesis. Researchers at the University of Cal-gary discovered that the release of prolactin spurs the growth of new brain cells in the front regions of the brain involved in smell. So Cabergoline may allow men to have multiple orgasms at the expense of
less brain growth. Sounds like a tough call to me.

Researchers are carrying out trials to investigate whether Cabergoline will have similar effects on women. Some anecdotal reports suggest that the drug has the potential to enhance the intensity of orgasms in both men and women.

demografx

  • Administrator
  • Hero Member
  • *****
  • Posts: 5226
  • All of us working together to defeat POIS!
Re: Cabergoline
« Reply #1 on: October 06, 2020, 04:45:13 PM »
[Re. Cabergoline]

“Report it. It really works. If you research it they think people that have POIS have a higher secretion of Prolactin than normal people after Orgasm. This causes a lot of the bad effects we feel. Cabergoline blocks the Prolactin from getting too high”

From a POISer who just now reported to me privately



« Last Edit: October 06, 2020, 04:57:56 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

  • Administrator
  • Hero Member
  • *****
  • Posts: 5226
  • All of us working together to defeat POIS!
Re: Cabergoline
« Reply #2 on: October 06, 2020, 04:54:51 PM »
From the same POISer, a highly regarded forum friend I’ve known for several years:


“I’ve been on it [Cabergoline] for three weeks. 5 O’s in 5 days. Feel okay physically but kinda tired. I would have been in shock without it. I would say it’s the best thing I’ve taken to combat symptoms. HCG and testosterone second”
« Last Edit: October 06, 2020, 04:57:14 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Muon

  • Hero Member
  • *****
  • Posts: 1570
    • MCAD Thread
Re: Cabergoline
« Reply #3 on: October 06, 2020, 05:04:32 PM »
There’s evidence that the release of prolactin in the brain, which surges during orgasm, promotes the growth of new neurons in the brain--a process called neurogenesis. Researchers at the University of Cal-gary discovered that the release of prolactin spurs the growth of new brain cells in the front regions of the brain involved in smell.

Neurogenesis in general may play a role in POIS if there is some truth to POISers being more intelligent than the average person. I wonder what the prolactin curve is for POISers vs healthy controls post-orgasm. Second note: There are mast cells in the pituitary gland.

Gabin

  • Newbie
  • *
  • Posts: 22
Re: Cabergoline
« Reply #4 on: October 08, 2020, 06:12:55 AM »
From the same POISer, a highly regarded forum friend I’ve known for several years:


“I’ve been on it [Cabergoline] for three weeks. 5 O’s in 5 days. Feel okay physically but kinda tired. I would have been in shock without it. I would say it’s the best thing I’ve taken to combat symptoms. HCG and testosterone second”

Thanks for the info, Demo, quite promising. Are you aware if prolactin levels have been tested prior to administration of cabergoline?

demografx

  • Administrator
  • Hero Member
  • *****
  • Posts: 5226
  • All of us working together to defeat POIS!
Re: Cabergoline
« Reply #5 on: October 08, 2020, 08:40:28 PM »
I’ll ask.
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

  • Hero Member
  • *****
  • Posts: 1070
Re: Cabergoline
« Reply #6 on: October 09, 2020, 08:54:53 PM »
My friend also has elevated prolactine levels, he took cabergoline, now his levels are normal but still has POIS.

From Gmail:

Hey, sorry, havn?t been on email lately or done really much of anything lately because of pois. This syndrome is clearly progressing leaving me with nothing but misery. Yes my prolactin levels are much lower now. 1.7 to be exact. The cabergoline has definitely done its job.

Javier.

demografx

  • Administrator
  • Hero Member
  • *****
  • Posts: 5226
  • All of us working together to defeat POIS!
Re: Cabergoline
« Reply #7 on: October 09, 2020, 09:10:24 PM »
My friend is also “on the border” with our 3-week rule. Let’s see what happens longer term.
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

dizzy

  • Full Member
  • ***
  • Posts: 154
Re: Cabergoline
« Reply #8 on: October 10, 2020, 12:02:55 PM »
Regarding side-effects, perhaps some possible ones can be found here:

https://en.wikipedia.org/wiki/Hypoprolactinemia
Male, INTJ. POIS symptoms: red eyes, ear-pain, anxiety, speech problems, pale/ugly skin, stiff neck, double chin, tinnitus, light sensitivity. POIS even after stimulation without O.

demografx

  • Administrator
  • Hero Member
  • *****
  • Posts: 5226
  • All of us working together to defeat POIS!
Re: Cabergoline
« Reply #9 on: October 10, 2020, 03:14:19 PM »
Thanks, dizzy!
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

  • Administrator
  • Hero Member
  • *****
  • Posts: 5226
  • All of us working together to defeat POIS!
Re: Cabergoline
« Reply #10 on: October 10, 2020, 04:54:21 PM »
From the same POISer, a highly regarded forum friend I’ve known for several years:


“I’ve been on it [Cabergoline] for three weeks. 5 O’s in 5 days. Feel okay physically but kinda tired. I would have been in shock without it. I would say it’s the best thing I’ve taken to combat symptoms. HCG and testosterone second”

Thanks for the info, Demo, quite promising. Are you aware if prolactin levels have been tested prior to administration of cabergoline?

His reply:

“I tested for it after I started taking it and my levels were normal. Remember that I started taking it for weightlifting. However, I would think if I was taking it for three weeks and my tested levels came back normal that my levels before that were high.”
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

  • Administrator
  • Hero Member
  • *****
  • Posts: 5226
  • All of us working together to defeat POIS!
Re: Cabergoline
« Reply #11 on: October 10, 2020, 05:07:43 PM »

His reply:

“I tested for it after I started taking it and my levels were normal. Remember that I started taking it for weightlifting. However, I would think if I was taking it for three weeks and my tested levels came back normal that my levels before that were high.”


Hi again, Gabin,
He just added:

“This is just my theory but I think people with POIS get flooded with Prolactin after Orgasm. They can have normal levels at all other times but they raise tremendously after O. What Cabergoline  has done for me is stop these large amounts from being released. I wish I could buy 10,000 doses and give them out for free to POISERS“
« Last Edit: October 10, 2020, 05:10:21 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

berlin1984

  • Sr. Member
  • ****
  • Posts: 266
  • Use Adaptogens and Antioxidants, they can help.
Re: Cabergoline
« Reply #12 on: October 11, 2020, 03:04:22 PM »
My friend also has elevated prolactine levels, he took cabergoline, now his levels are normal but still has POIS.

I experimented with Vitex agnus-castus but felt it didn't change anything related to POIS either :-(

(I'm not claiming it has the same mechanism in the body as cabergoline / Dostinex)
Please vote on: https://poiscenter.com/forums/index.php?topic=3386.0
(There's real science behind it, not Astrology..)

My Protocol