Author Topic: Excessive serotonin/tryptophane just after orgasm ?  (Read 104 times)

b_jim

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Excessive serotonin/tryptophane just after orgasm ?
« on: February 28, 2019, 12:47:49 PM »
I'm a bit depressed  and my sleep is bad since some weeks. So I tried a little home remedy : pumpkin seeds + carbs at 5'clock. To try to boost serotonin and melatonine.
Scientific studies show a little positive effect with this.

But after orgasm, I had bad symptoms. I didn't had such symptoms since many months. I even didn't took taurine since 1 month.

I simply wonder if I don't have an excessive tryptophane/serotonin levels just after orgasm. (and maybe the opposite the day after, explaining dream-like state).

Tryptophane is converted into serotonine in gut (90%) by tryptophane hydroxylase (TPH) enzyme. And can't cross brain-blood barrier.
So an excess of serotonin is absorbed by blood platlets (trombocytes) and stored in blood.

But when this serotonin is excessive it causes :
-inflammation by activation of T-Cells and a release of pro-inflammatoy cytokines
- vasoconstriction and migraines

In fact another role of serotonine (which I didn't know) is to generate a vasoconstriction when you cut yourself (I mean with a knife)

Role of vitamind D :
There are 2 TPH :
TPH 1 : in gut and TPH 2 in brain.
Vitamin D down-regulates TPH 1 and up-regulates TPH 2.
It means vitamin D enchances serotonin in brain but avoid serotonin excess in blood.
And it explains why vitamin D reduces inflammation by this pathway.

Possible remedy  ?
If my theory works, supplements or food with glycine or gelatin might reduce Pois symptoms.



 
« Last Edit: February 28, 2019, 01:13:13 PM by b_jim »
Taurine = Anti-Pois

Nas

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Re: Excessive serotonin/tryptophane just after orgasm ?
« Reply #1 on: February 28, 2019, 01:01:56 PM »
B_jim, I'm a bit confused, are you having these symptoms because you have an excess of Tryptophan or don't have an excess of Tryptophan?

b_jim

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Re: Excessive serotonin/tryptophane just after orgasm ?
« Reply #2 on: February 28, 2019, 01:05:24 PM »
As I said I'm a little depressed since some week => it might show a low level of serotonin/tryptophan in brain.

But my "remedy" seems to influence negatively my Pois by excessive tryptophan/serotonin in gut.

Sorry my english is bad, I'm very tired.

Taurine = Anti-Pois

Nas

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Re: Excessive serotonin/tryptophane just after orgasm ?
« Reply #3 on: February 28, 2019, 01:12:59 PM »
Ah ok makes sense.

b_jim

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Re: Excessive serotonin/tryptophane just after orgasm ?
« Reply #4 on: February 28, 2019, 01:18:41 PM »
There is a condition of real serotonin syndrome (probably after taking drugs like ecstasy=mdma...):

I just put the list of symptoms :


    Agitation or restlessness
    Confusion
    Rapid heart rate and high blood pressure
    Dilated pupils
    Loss of muscle coordination or twitching muscles
    Muscle rigidity
    Heavy sweating
    Diarrhea
    Headache
    Shivering
    Goose bumps

And when the symptomes are very heavy (dangerous) :

    High fever
    Seizures
    Irregular heartbeat
    Unconsciousness


Very strange I think...
Taurine = Anti-Pois

b_jim

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Re: Excessive serotonin/tryptophane just after orgasm ?
« Reply #5 on: February 28, 2019, 01:27:23 PM »
I had a very bad experience today.  :(
I want to start gelatin/glycine tomorrow.

It may explain why Vit D deficiency seems to increase Pois (Pois stronger during winter). It may explain why sugar triples my Pois and give me diarrheas in and out of Pois.
Maybe there is a link with the niacin cure too....

Eosinophilia–myalgia syndrome
https://en.wikipedia.org/wiki/Eosinophilia%E2%80%93myalgia_syndrome


uP:
I try to cook food with industrial gelatin but it's very poor : only 13gr of gelatin and it's not natural.
Boring
I will to try a grandmother remedy : bone soup.

Up 2 :
My insomnia is called Advanced sleep phase disorder.

« Last Edit: March 07, 2019, 01:02:42 PM by b_jim »
Taurine = Anti-Pois

Nas

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Re: Excessive serotonin/tryptophane just after orgasm ?
« Reply #6 on: March 01, 2019, 05:02:34 AM »
Looking forward for your glycine trial b_jim.