Quantum, that is incorrect. First off CAP is a very new finding and not very established. It's a very general finding that links the autonomic system with the immune system. Dysautonomia illness has the most autonomic dysfunction out of all illnesses combined. I know thousand with the disease and they don't all have immune problems of any kind. Some have very severe parasympathetic dysfunction too. Cholinergic means acetycholine or parasympathetic chemical transmitter. In many people with dysautonomia they have co existing autoimmune illnesses. And dysautonomia currently is being studied right now as a stand alone autoimmune illness that affects autonmic receptors.
In any case you can't have vagus problems and only have pois symptoms. It woldn't make sense at all in any way no matter what crack pot scientist tries to explain it. The vagal nerve interacts with the heart, veins, lungs and would cause symptoms that pois people are simply not reporting at all.
Does POIS cause autonomic dysfunction? In my case not directly, yet I have severe autonmic dysfunction. Does POIS cause autoimmune type of problem, I believe so. Can autoimmune inflammation type of probems affect the autonomic nervous system. I believe I am living lroof of that. I think after year of inflammation it eventually got into my autonomic nerves. Do all pois people get dysautonomia, I dont know any! Do all dysautonomia people get pois, out of the thousands I know none else have pois.
Most likeley pois is an autoimmune illness of sorts in that the allergic response we get to O is triggerring autoimmune type of inflammation or attacks. Possibly it is a vasculitis inflamming our veins which reach into our brains and throughout all our organs. Or through another pathway like the lymphatic sysmptom.. The Poly Vagal Theory is a classic case of twist reality to conform whatever a person wants. They mix in some real stuff and it sounds terrific but in reality that is only to an untrained person. I wish it was true but it's not. Sorry
Hi Disaster,
I am sorry to have read in other threads that you have a very severe case of POIS, as well as two auto-immune illnesses on top of that. I wish you to find relief for all of your conditions, as soon as possible. Also, iI is totally ok that you do not agree with the Polyvagal theory and the new findings about the CAP. However, even if you experience much pain, and that it can make you edgy, and even if you do not agree with the Polyvagal Theory and about CAP, that does not justify you saying things like " It woldn't make sense at all in any way no matter what crack pot scientist tries to explain it." and "The Poly Vagal Theory is a classic case of twist reality to conform whatever a person wants. They mix in some real stuff and it sounds terrific but in reality that is only to an untrained person" . Let me remind you of the first community guideline of the poiscenter forum: " Be nice and supportive: POISCenter works because we support and care for one another. Be nice, and be supportive. Do your best to respect differing points of view." ( (
http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259 ). All members here are suffering from POIS. They have gathered $33 000 in order to found a study on POIS, which is a great accomplishment in itself. It happens that the ongoing Rutgers study, the one you wanted to be part of, is partly based on the Polyvagal theory and the role of the vagal nerve in POIS, and the researchers leading it have a positive perception of the Polyvagal theory, and part of the study experimental design is based on it. NORD, a very respectable organization, have chosen the Rutgers team study among the all the POIS study projects they have received, as the most valuable one. So, even if your do not agree with this, I invite to voice your opinions with more respect, as they are not facts, but opinions. Simply explain that you do not agree, and why, and what is your own opinion. And, keep an open mind, and a friendly attitude, being aware of the potential emotional and relational effects of what you express, and, importantly, of the words you choose to express it.
As Jowlawerence have just written in his post to you, the truth is no one knows what exactly causes POIS symptoms. I have no problems that you have clear ideas about what POIS is not and what it may be. We share our ideas, whatever they are. No one here can claim to be an authority on POIS, and it is better to share what you think about POIS for what it is, that is, hypothesis. You can also share what has been working - or not - for you. That's ok if you know a lot about neurology and immunology, and it is of great value if you share here what you know and how it relate to POIS.
As I said in the first post of this thread, I have opened it so all members can get at least a minimum of knowledge about the Polyvagal Theory, so we all have a better understanding of the results of the study, when they will be out. I, personally, knew almost nothing about this theory up to a few weeks ago, it didn't know neither about the Cholinergic Auto-Immune Pathway ( but I did know for a long time about HRV). So, this is a thread to get familiar with PVT, CAP, and all things related, and, hopefully, share our ideas on how they can help understand POIS pathophysiology. It is in no way an attempt of mine to prove - or not - that the Polyvagal theory or the CAP are THE way to go in order to solve the POIS problem. We are only in the process of getting to know more about it, and see what it can bring as a benefit for us POIS sufferers, and, prepare to get the most out of the study results the members have paid for.
This thread is neutral, as I am, about the value of PVT and CAP. As a matter of fact, my current take on the pathophysiology of POIS does not include PVT elements or CAP, as I am just currently getting to know these better. I have already express my views elsewhere on this forum, and my hypotheses about POIS are still a "work in progress" (If interested, see
http://poiscenter.com/forums/index.php?topic=2078.msg16431#msg16431 for more info of my personal, current views on POIS pathophysiology ) . You can go ahead and do the same and start your own thread, where you can propose your own hypothesis about the pathophysiology and treatment of POIS.
We are all here, together, to do our best with the information we have, and from our empirical successes and fails. Slowly but surely, I am sure we will solve the POIS puzzle. In the meantime, I wish you will find ways to get some relief for your POIS symptoms, Disaster.
