POIS Cause/Treatment Discussions > Auto-Immune Causes and Treatments


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In the latest study i have read :

The symptoms of POIS are similar to those of “opioid withdrawal syndrome,” which includes physical (flu-like symptoms, perspiration, and rhinitis) and psychological symptoms (anxiety, depression, and difficulty concentrating). These symptoms can last 2–7  days [15]. Opioids are involved in mediation of positive affective states  generated by the execution of sexual behavior [16]. The ?-opioid receptors are thought to play a crucial role in controlling this behavior [17]. We supposed that patients suffering from POIS may have a disorder of the endogenous ?-opioid receptor system. Orgasm consumes large amounts of endogenous opioids in these patients, which causes a series of symptoms similar to opioid withdrawal symptoms."

Did someone try Low Dose Naltrexone cause it is used in many autoimmune conditions?

Interesting, Starsky!

Can you post the link of the last study you read, please ?
I have wrote several texts about opiate whidrawal syndrome and the "sexual hangover".
But I took low opiate meds for a lumbago (codeine) and the effects were strange and negative. Bad experience with valerian root too and alcohol.

Its the latest chneese study, PM and i will email you it back.

Thanks. That's a very, very good study.
I remember I sent a mail to dr Waldinger to ask him if there is a possible role of opioid system in Pois. But once again, my experience with codeine didn't convinced me.
Dr Jiang suggestion is very simple : orgasms use a lot of endorphin and it creates a lack of endorphins like opiate withdawal syndrome. This is not the first time this theory is suggested but the first time by a doctor !
Seeing that 99% Poisers are men and considering animus surgery, is there endorphins in semen; in large quantity ?
Anyway, is this suggestion is correct the cure is a problem. You can't rebalance the system with exogenous endorphins without creating another withdrawal.

The link with sugar is clear.
I don't know if there is a link with taurine.


Semen / opiates

--- Quote --- But sperm comprise only about 3 percent of semen. The rest is seminal fluid: mostly water, plus about 50 compounds: sugar (to nourish sperm), immunosuppressants (to keep women's immune systems from destroying sperm), and oddly, two female sex hormones, and many mood-elevating compounds: ENDORPHINS, estrone, prolactin, oxytocin, thyrotrpin-releasing hormone, and serotonin.
--- End quote ---

--- Quote ---The basis for all this is two interesting facts. First, semen contains a very large number of chemicals, including ENDORPHINS (which resemble OPIATES and reduce pain and change how we feel emotionally), hormones, and neurotransmitters (which work in the brain).
--- End quote ---

And the best one for the end :

--- Quote ---Seminal plasma contains high levels of opioid peptides and both seminal plasma and endogenous opioids can influence the immune system.
--- End quote ---


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