POIS Cause/Treatment Discussions > Auto-Immune Causes and Treatments

LOW DOSE NALTREXONE

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Starsky:
In the latest study i have read :

The symptoms of POIS are similar to those of “opioid withdrawal syndrome,” which includes physical (flu-like symptoms, perspiration, and rhinitis) and psychological symptoms (anxiety, depression, and difficulty concentrating). These symptoms can last 2–7  days [15]. Opioids are involved in mediation of positive affective states  generated by the execution of sexual behavior [16]. The ?-opioid receptors are thought to play a crucial role in controlling this behavior [17]. We supposed that patients suffering from POIS may have a disorder of the endogenous ?-opioid receptor system. Orgasm consumes large amounts of endogenous opioids in these patients, which causes a series of symptoms similar to opioid withdrawal symptoms."


Did someone try Low Dose Naltrexone cause it is used in many autoimmune conditions?

demografx:
Interesting, Starsky!

b_jim:
Can you post the link of the last study you read, please ?
I have wrote several texts about opiate whidrawal syndrome and the "sexual hangover".
But I took low opiate meds for a lumbago (codeine) and the effects were strange and negative. Bad experience with valerian root too and alcohol.

Starsky:
Its the latest chneese study, PM and i will email you it back.

b_jim:
Thanks. That's a very, very good study.
I remember I sent a mail to dr Waldinger to ask him if there is a possible role of opioid system in Pois. But once again, my experience with codeine didn't convinced me.
Dr Jiang suggestion is very simple : orgasms use a lot of endorphin and it creates a lack of endorphins like opiate withdawal syndrome. This is not the first time this theory is suggested but the first time by a doctor !
Seeing that 99% Poisers are men and considering animus surgery, is there endorphins in semen; in large quantity ?
Anyway, is this suggestion is correct the cure is a problem. You can't rebalance the system with exogenous endorphins without creating another withdrawal.

The link with sugar is clear.
I don't know if there is a link with taurine.

--

Semen / opiates


--- Quote --- But sperm comprise only about 3 percent of semen. The rest is seminal fluid: mostly water, plus about 50 compounds: sugar (to nourish sperm), immunosuppressants (to keep women's immune systems from destroying sperm), and oddly, two female sex hormones, and many mood-elevating compounds: ENDORPHINS, estrone, prolactin, oxytocin, thyrotrpin-releasing hormone, and serotonin.
--- End quote ---


--- Quote ---The basis for all this is two interesting facts. First, semen contains a very large number of chemicals, including ENDORPHINS (which resemble OPIATES and reduce pain and change how we feel emotionally), hormones, and neurotransmitters (which work in the brain).
--- End quote ---

And the best one for the end :
http://www.ncbi.nlm.nih.gov/pubmed/3156145


--- Quote ---Seminal plasma contains high levels of opioid peptides and both seminal plasma and endogenous opioids can influence the immune system.
--- End quote ---

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