Careful with the niacin doses as 100mg is the 625 % daily amount that a human needs..It may damage the liver or cause some adverse symptoms..Taking 300mg or 400mg a day is approximately 2000% of daily need..I think thats a lot..
---------------------
That is huge - Ill tell him right away. I dont know how to reply to you using your quote (Chris)
Not to minimize the potential for problems, but at least to put it more into context:
For a normal person, the MDR is only 16.5mg. It is a Minimum Daily requirement, not maximum daily requirement.
Most studies indicate that liver damage is not a real threat under 1000mg per day. After that they suggest that
one should have regular liver exams.
We suggest that anyone taking niacin for POIS should have liver tests done maybe twice or more a year anyway.
One should always take their own situation into account. We have had some with niacin allergies, and cannot
take ANY niacin. In some situations it can be dangerous. The doctors would know.
That said, most doctors would probably point blank, without really understanding the mechanisms say, "Why should
you exceed the MDR?", and may suggest not taking it without really taking your case into full consideration.
We suggest not taking more than required, trying to find a minimum dose that gives you optimum relief and have a
regular checkup to make sure everythings fine.
I've been taking niacin now for at least a year (as required... always trying to keep doses as close to the 100mg
as I can), and have had no ill effects to the liver, which I check twice a year, or skin or any other functions of
my body. Others have taken it for POIS for 3 or 4 years with no adverse effects. A few have taken it once with
scary problems, so take it responsibly.