Testosterone

[Muon]

How about a nerve conduction study?

[demografx]

How about a nerve conduction study?

Great idea! Wish we weren’t so cash strapped to do…..m  o  r  e (like this).

[demografx]

[TRT + Cialis Update]
…I just “survived” 2 4 POIS events in 2 5 days, without horrendous symptoms!…

Yet another “successful” POIS morning!

Hard to believe, at my age, that I finally found a very effective anti-POIS method!

Worth waiting 60 years? No comment!

[Andre2505]

Hi guys,Im Italian, this is the first time I've seen this topic and I've seen that it's mostly about testosterone, I've done blood tests and I have pretty good total and free testosterone, pero I did the tests 3 days after ejaculation, so I wasn't really in the serious pois state. What I want to know is whether some testosterone therapies can come in handy for me as well. Or do you guys do them just because you have low testosterone? Thank you

[Muon]

How about a nerve conduction study?

Great idea! Wish we weren’t so cash strapped to do…..m  o  r  e (like this).

Can they do some testing on you?

[Samir]

I haven't read everything in this thread related to testosterone, but one definitely known link is low T and hot flashes.  Apparently it is common with androgen deprivation therapy for prostate cancer, so the physiology is understood.  However, I have not found any research related to general low T and hot flashes without androgen deprivation therapy for prostate cancer.

https://www.health.harvard.edu/mens-health/hot-flashes-in-men-an-update

One thing that would be an interesting area of research would be to see if prostate cancer patients undergoing androgen deprivation therapy have more POIS symptoms than those not undergoing androgen deprivation therapy.  Might not find any strong link since the body is all whacked out anyways during cancer treatment, but if a strong relationship is found, it could shed some light on how T plays a factor in POIS.

[demografx]

I intend this post to serve as a correction to all my above posts in this testosterone thread and elsewhere - - that enthusiastically ‘promoted’ the use of Benadryl (diphenhydramine) for POIS treatment. It did provide the relief that  I described - - but the side effects are not worth it, especially at my age (78) and especially since cognitive decline is a challenge for me and many, many other POISers.

…I'm testing diphenhydramine at the moment.

Diphenhydramine worked minor miracles for me after my open heart surgery 12 yrs ago.

Unfortunately, I became addicted to it and even wound up in the ER/extended stay/hospital observation for excessive dosage use.

Nevertheless, I continued taking it in spite of *multiple* MD (primary care + specialists’) warnings - - warnings to avoid it - - even at moderate doses.

I’m now off it, and feel better for it. But my primary concern (cognitive impairment) might not be the same as yours.

A Harvard health study:
https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-201501287667

[largooo]

i havent read the whole post, so i dont know if that already been taken in consideration,
but it seems that abstinence (at least 3 weeks ) does produce elevated level of testosterone in males.
that means for a lot of poisers who are abstinent, a high level of testosterone could be normal but also that a normal lvl of testosterone could be considered as low
and  probably many of us have missed this

and this could join my theory turning around an hormonal problem coming from a specific gland or directly from hypothalamus/pituitary problem

many poisers got hormonal disorders (testosterone / cortisol / thyroid hormones / prolactin / etc..)
and glands that produce those hormones (testicular glands / adrenal glands / thyroid  glands / etc..) are all dependant from one thing  : hypothalamus/pituitary glands (->see picture)

an accident / injury / infection / intoxication and for sure burnout / traumatic stress / chronic stress as many of us have, could affect and damage hypothalamus/pituitary and disrupt hormones production (too much or too less)

and the point here and and most important is that all thoses hormones also all interact with each others

for example :
cortisol stop/block testosterone production
dopamine supress prolactine
etc ...

so if only one thing is disrupted  everything could be broken

that could explain why sometimes treatment like testosterone replacement therapy (for those who got this hormonal disorder)  gives some result reducing their POIS symptoms  but not for every one and not always 100%


if the problem come from an injured hypothalamus/pituitary that can't send normal order other gland and hormone production cant be affected


i havent doing thos research yet but,
is there some case of poisers doing some MRI (Magnetic resonance imaging) of hypothalamus/pituitary to check any injury ?

[sartre02]

@demo and everyone who reads this :
I am 30 years old and POIS ruined my life ! I never wanted kids sincechildhood which makes me think I had depression/POIS since early age
I probably have the most severe complex case of POIS in this website..
I am self medicating like "limitbreaker" , all the doctors refused and what am I supposed to do ? agree and suffer ? or self medicate and stop suffering ?
I am aware of the risks , to hell with kids, why should I care to have kids when I am unable to live happily ? tried so many and none come to the effectiveness of high TRT. I am also thinking about trying "dianabol" for mood and joint pain which is famous for , micro dosing "trenbolone" for better CNS function, and proviron to see if it improves mood (SHBG mechanism)..
I tried dexamethasone 8mg injection, felt better but repeated injections can cause serious immune dysfunction.
When I am iN pois ? EVEN ritalin, stops working, my brain shuts down. coffee doesnt work nor nicotine
I am from north africa..no one here knows what POIS is .. I was always late in school , difficulty learning, depressed, POTS and sleeping 12 hours since childhood , I probably had this since early age , but no where near the age of 20 , FULL BLOWN POIS. HELL.
if I poop, sperm comes out , I get POIS
if I dont poop for a week I feel like a million bucks !!
I was eating 1 meal a day just to poop less , because the more I poop , I leak sperm and I don't allow my body to recover , basically never ending POIS....to hell with kids and doctors. TRT ..and maybe XOLAIR if available...currently trying to find it ..no success

I read yourbodybuilder post about 800mg dose that wiped out his pois
can you detail , is it 800 daily or weekly ? does he use any other compounds like trenbolone that are known for increasing CNS activation which is exactly the opposite of what POIS does
I had 600 ng/dl , which is more than normal
I took 200 mgs per week of TRT and after weeks I felt 70% better , it put me at 1400ng/dl
currently I am on 250 and wonder if 500 per week would get me to 100% remission

hypothetically , suupose that 500 per week is the answer
I am well educated and a bodybuilder my self
more testosterone would mean health risks and monitoring is required , namely increased blood viscosity through high hematocrit (erythropoesis) does anyone know how sustainable this solution is if I donate blood every 3 months to reduce high hematocrit ?
I know some people on youtube who are on 500mg for years like "milo sarcev" he is over 50 years
lipid levels can be monitored too and improved through cardio but my GOD!! if 500 was the answer !!
I asked my doctor about silodosin to help stop leaking sperm while pooping he sais it doesnt prevent it.
Does anyone know which medication can help close the leaking of sperm while pooping ?

[demografx]

@demo and everyone who reads this :
I am 30 years old and POIS ruined my life ! I never wanted kids sincechildhood which makes me think I had depression/POIS since early age
I probably have the most severe complex case of POIS in this website..
I am self medicating like "limitbreaker" , all the doctors refused and what am I supposed to do ? agree and suffer ? or self medicate and stop suffering ?
I am aware of the risks , to hell with kids, why should I care to have kids when I am unable to live happily ? tried so many and none come to the effectiveness of high TRT. I am also thinking about trying "dianabol" for mood and joint pain which is famous for , micro dosing "trenbolone" for better CNS function, and proviron to see if it improves mood (SHBG mechanism)..
I tried dexamethasone 8mg injection, felt better but repeated injections can cause serious immune dysfunction.
When I am iN pois ? EVEN ritalin, stops working, my brain shuts down. coffee doesnt work nor nicotine
I am from north africa..no one here knows what POIS is .. I was always late in school , difficulty learning, depressed, POTS and sleeping 12 hours since childhood , I probably had this since early age , but no where near the age of 20 , FULL BLOWN POIS. HELL.
if I poop, sperm comes out , I get POIS
if I dont poop for a week I feel like a million bucks !!
I was eating 1 meal a day just to poop less , because the more I poop , I leak sperm and I don't allow my body to recover , basically never ending POIS....to hell with kids and doctors. TRT ..and maybe XOLAIR if available...currently trying to find it ..no success

I read yourbodybuilder post about 800mg dose that wiped out his pois
can you detail , is it 800 daily or weekly ? does he use any other compounds like trenbolone that are known for increasing CNS activation which is exactly the opposite of what POIS does
I had 600 ng/dl , which is more than normal
I took 200 mgs per week of TRT and after weeks I felt 70% better , it put me at 1400ng/dl
currently I am on 250 and wonder if 500 per week would get me to 100% remission

hypothetically , suupose that 500 per week is the answer
I am well educated and a bodybuilder my self
more testosterone would mean health risks and monitoring is required , namely increased blood viscosity through high hematocrit (erythropoesis) does anyone know how sustainable this solution is if I donate blood every 3 months to reduce high hematocrit ?
I know some people on youtube who are on 500mg for years like "milo sarcev" he is over 50 years
lipid levels can be monitored too and improved through cardio but my GOD!! if 500 was the answer !!

From my friend:

“The 800mg I take is weekly. I feel of all the testosterone products that Propinate works the best. It’s in and out of the system in 3 days. It also works well if you have two orgasms close together(one or two days) you can double your dose for a few days and get relief. Like you my natural test was fine. But the higher dosage of test completely wiped out my brain fog and lethargy. This was a godsend for me because I run my own business and I had to sleepwalk through meetings for years. I pushed it and had 3 or 4 orgasms in a week and the only side effect I had was real sore joints. But no mental side effects which is huge for me. I feel like POIS gave me a mental disorder so this success was huge for me. I also recommend a 2mg dose of HCG everyday and 2mg of HGH. If your a bodybuilder you will know where to get it. I strongly recommend staying away from Trenbalone. Yes, it would work as well as Testosterone but it will destroy your organs. Testosterone may have negative effects on your heart but has not shown to have alot of negative effects on your organs. Many people get irreversable damage from Trenbalone when Testosterone will do the job. Good luck”

[sartre02]

Many thanks to you and your friend.
what about dianabol for mood ?
I tried recombinant LH (hcg) 6000 units !! the day before orgasm...didn't help ...
I'll see if HGH will do the trick..
@demo and evryone else .. : do you know which med can help stop sperm leaking while poop ? meaning to sort of close the valves ?
I was abstaining for years and years and maybe pelvic floor muscles got weak (can't strengthen them )
also with regards ro "dexamethasone" how frequently can I use it without damaging my immune system ? leaflet says recurrent injections may cause low cortisol
also any sleeping meds that help insomnia that don't disturb "deep sleep REM sleep" ?

[Ani1946]

dexamethasone vs trt, which one helped you more? @sartre02

[sartre02]

TRT for sure
dexamethasone is dangerous !! it should be used only in EXTREME RARE cases , the leaflet says repeated use can cause low cortisol and basically it kills your immune system and you will depend on it for life ! plus it may affect and cause severe depression..
honestly dexamthasone in the morning it made me feel good , and at night it gave me anxiety..
it makes sense.. half life is 4 hours...and can remain for up to 12 hours in system or more
I took injection 8 mg
I recommend you try xolair its far better I heard, Im looking for it currently
Dexa is so dangerous that I stopped it
prednisone I took 30mg day to see any improvement..better but not enough..
dexa and prednisone can shut down the immune system ,
I am going to try 500mg TESTOSTERONE PER WEEK and see if the dopamine/anti inflammation properties can beat pois..
I dont recommend 500 to anyone, unless you know what you are doing, a lot of blood work needs to be monitored , but with pois ? to hell with fertility ...whats the point of existing and not being functional
I read many reddit posts corrected by wellbutrin , it makes sense that POIS may be a deficiency of adrenaline norepinephrine..
I would love to see what people like @demografx and @Quantum have to say about this..
I was always sleeping 10/12 hours per night since childhood..and even that not refreshed
this is where HIGH TRT CAN PLAY !
it makes you recover quicker , muscle synthesis , cns recovery, neuron recovery , dopamine synthesis and high estrogen causes some anxiety and more CNS activation giving you that get up and go...which is not curing pois but definitely OVERRIDES it...
Proviron/arimidex can help with estrogen control

[sartre02]

Every POISER needs to know this....if you tried everything to no avail and you did not cure POIS , think about TRT..even if you have normal levels...
I had more than enough , and after pois , my brain does not respond to coffee its like drinking water
and after TRT , coffee works..and I drink faaar less.
I am 30 years male , I had 600ng/dl...
with TRT 200mg/ week I was at 1400ng/dl
it's not a cure....but its the best patch you can find
doctors refused to give me TRT
I am a bodybuilder , I have other ways to get TRT
if you want fertility...and you accept to suffer just to have kids...thats your choice..
I don't have time for this s**t
but I know bodybuilders who take TONS of steroids for YEARS !! and manage to get kids anyway...see ronnie coleman , dorian yates..
POISERS NEED TO KNOW THAT TRT CAN HELP THEM
I cannot believe people end their lives and not give TRT a try...
some say , you cannot promote TRT and start talking about all medical legitimacy...
Oh and suicide is better ?!!!
how about SSRIs that can permanently mess up the neurochemistry...?
I tried prozac before , it gave me permanent indigestion , years now after stopping it ! and I still have it !
 -*****
if you are going to try TRT...you will see a difference in 6 weeks but it takes 3 months to see full anti inflammation/dopamine effect
and it after this time you don't see a difference , perhaps you are a hyporesponder , medically speaking some people require 500mg per week to reach 1200ng/dl which is TRT but these are rare cases of a defect in RNA transcription
give it at least 3 months...
lower estrogen to 20-30 pg/dl ...high estrogen prevents from feeling full effect. I take1/4 of 1mg for 200mg per week , if you take arimidex and you feel bad ,it means you crushed you estrogen too low , arimidex is extremely powerful and potent , try lowest dose possible and dont use it in the beginning , only after 3 months if you don't see a difference.
TRT needs to be dialed in , but when it works !! boy !!!! you feel on top of the world. of course , cardio and healthy eating is needed
I used to smoke and it blocked the effect of TRT
quit , dont take any form of nicotine to feel the full of effect of TRT
you may feel insomnia in the beginning but thats normal because of the insane amount of energy you are getting...after a while your body gets used to it.
if you still dont feel TRT , check your SHBG levels if too high , lower them using proviron
if you get acne, don't take accutane , its too risky , just lower your fat/oily food intake and give it 6 months you will not break out anymore , people need to know , that acne in TRT is only a result of the SUDDEN shift in hormones
now Im at 8 months TRT and feel 80 % better if not more
if you still can't feel TRT after 3 months , make sure you test/supplmenet DHEA/PREGNENOLONE/HCG
HGH I also heard 2 units per day is effective ! @demo can chime in

[sartre02]

Funny note : I had the idea of TRT after eating 3-5 red raw onions like apples ! NOT CHOPPED ! eat them as quick as possible do not let them evaporate the gases , and eat them on empty stomach with a very small glass of water before hand
if you drink too much water, it comes into contact with acid  and you lose benefits
if you do as I said ! next day you will have POIS vanish
ps : the more you blow your nose , the more effective ! it seems some way of clearing out toxins
it worked for years for me..
I researched , onions stimulate FSH/LH
fsh/lh create TESTOSTERONE
TRT miracle
ps : I had good functioning FSH/LH prior

[b_jim]

I cannot believe people end their lives and not give TRT a try...

 that acne in TRT is only a result of the SUDDEN shift in hormones

Two points I like in your post.
Every thing is better than suicide.
And acne after ejaculation can be explained by the hormones schift, very good job.

[demografx]

…I cannot believe people end their lives…

…Every thing is better than suicide…

TWO (2) MENTAL HEALTH RESOURCES FOR ANYONE NEEDING SUPPORT IN A CRISIS.

[1.]

I texted the Suicide Prevention Hotline
(by texting Hello to 741741) to test their system.

It works well.

They also offered me this description to post @ POISCenter:

"We are a support line for all ages, providing free, 24/7 crisis support through text messaging. Learn more at:

For more texting info:
https://bit.ly/CTLfaq_ref


For telephone chat:
Click here:
1.800.273.8255




For list Of International Suicide Hotlines:
http://www.suicide.org/international-suicide-hotlines.html

[2.]

988 (telephone#) is a new system (U.S.) that recently went live to help people reach help in a mental health crisis.

[demografx]

Quote from NSF/POIS thread forum member:
“Every day before breakfast and lunch, 1x57g capsule of Taurine and magnesium 900mg with a bit of water (room temp),”

Quote from b_jim:
Taurine is the KEY of my Pois. It makes a HUGE difference.
It's like if taurine is "pumped" after ejaculation to "regenerate" something (testosterone ? semen ?).

But you made a mistake in dose, 1x57g is not correct

b_jim, I saw this old post from our predecessor-forum, The Naked Scientists Forum/POIS thread, in 2015.

Has your view of taurine changed? What is the suggested dosage today please?

[b_jim]

No, I didn't change my point of view : after 10 years of taurine supplementation, this is the best supplement for my Pois.
500mg is enough, 100-200g of fish makes the job.

But I have to be honest, we are only 5 to 10 guys here to have a real improvement with taurine.
So we may have an innate (genetic?) problem with taurine biosynthesis.

And then the lack of taurine is the limiting factor of the real cause of Pois : hormone or neurotransmitter falling after O .

[b_jim]

Even though I can't believe it could work, I'm testing cold showers every morning