Testosterone

[demografx]

Day Zero sleep/rest & Infertility Alert edits:









After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

[demografx]

After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

========================

This morning, POIS “struck”, and I followed my protocol above. I did not rest/stay in bed/force sleep and was busy with errands all day.

I have “miraculously” been POIS-free all day!!

Placebo effect? Time will tell!

Activity vs passivity was the only difference today.

[demografx]

Prior to my testosterone treatment I tried Levitra, an erectile dysfunction med, a PDE5 inhibitor - - as an experimental treatment for my POIS.

It worked.

Then it eventually stopped working.

Luckily, I found testosterone, which I’ve been on for 11 years - - for POIS.

Today, I thought I’d give PDE5 another chance, so I tried Cialis, minimum dose. Too early to tell. If it doesn’t improve my POIS in Quantum’s suggested testing timeline, you won’t hear any more about it from me in this thread.

Best,
Demo

Quantum, it’s been 5 months since I posted this and - - after yesterday’s POIS-episode-and-Cialis-effective-treatment-supplementation, i hope we can add this to your POIS-types Chart & Treatment Methods.

Thank you,
Demo

My theory: Cialis speeds up POIS-induced refractory-period-sluggishness, which I think causes my POIS symptoms:

from Google search:
“Erectile dysfunction drugs called phosphodiesterase type 5(PDE5) inhibitors—which include meds like Viagra, Cialis, and Levitra—may also boost sperm quality in men whose swimmers aren't up to snuff, a new meta-analysis from China concludes.”
2017.

[Quantum]

Prior to my testosterone treatment I tried Levitra, an erectile dysfunction med, a PDE5 inhibitor - - as an experimental treatment for my POIS.

It worked.

Then it eventually stopped working.

Luckily, I found testosterone, which I’ve been on for 11 years - - for POIS.

Today, I thought I’d give PDE5 another chance, so I tried Cialis, minimum dose. Too early to tell. If it doesn’t improve my POIS in Quantum’s suggested testing timeline, you won’t hear any more about it from me in this thread.

Best,
Demo

Quantum, it’s been 5 months since I posted this and - - after yesterday’s POIS-episode-and-Cialis-effective-treatment-supplementation, i hope we can add this to your POIS-types Chart & Treatment Methods.

Thank you,
Demo

My theory: Cialis speeds up POIS-induced refractory-period-sluggishness, which I think causes my POIS symptoms:

from Google search:
“Erectile dysfunction drugs called phosphodiesterase type 5(PDE5) inhibitors—which include meds like Viagra, Cialis, and Levitra—may also boost sperm quality in men whose swimmers aren't up to snuff, a new meta-analysis from China concludes.”
2017.

If I understand it well, Demo, you are still taking Testosterone, but by adding Cialis, you speed up the recovery time, right ?  If so, can you give me more details ( duration of POIS with TRT only, and duration with TRT+tadalafil(Cialis) ?  Then, I will have enough details to update the TRT section of my POIS Types Chart.

[demografx]

If I understand it well, Demo, you are still taking Testosterone, but by adding Cialis, you speed up the recovery time, right ?

Yes

If so, can you give me more details ( duration of POIS with TRT only, and duration with TRT+tadalafil(Cialis) ?  Then, I will have enough details to update the TRT section of my POIS Types Chart.

As I mentioned in a previous post, I’m still experimenting with dosages and timing

So far, recovery with TRT alone is 2 days, with taladafil, less than a day.

Intensity of symptoms is less with TRT + taladafil.

Part of the equation I’m still working on is prior ideal abstinence and dosages of TRT  and dosages of taladafil. I’ve increased both.

Perhaps I should determine a stable formula before you’re able to cite TRT + taladafil.

Also, CPAP machine and daytime sleep induction (Tylenol + Benadryl) are variables.

[Quantum]

I have made an update in the "Notes" section of the TRT Type, in my chart:

"In 2021, Demografx added tadalafil 20mg ( Cialis) to his anti-POIS regimen.   Recovery with TRT alone was 2 days, and when using TRT+taladafil, recovery is less than a day.  Also, the intensity of symptoms is less with TRT + taladafil. ( note: considering that the duration of effect of tadalafil is around 36 hours, the timing of this medication intake is not a concern)"

If you get more detailed information or a more stable formula over time, just let me know.

[demografx]

I have made an update in the "Notes" section of the TRT Type, in my chart:

"In 2021, Demografx added tadalafil 20mg ( Cialis) to his anti-POIS regimen.   Recovery with TRT alone was 2 days, and when using TRT+taladafil, recovery is less than a day.  Also, the intensity of symptoms is less with TRT + taladafil. ( note: considering that the duration of effect of tadalafil is around 36 hours, the timing of this medication intake is not a concern)"

If you get more detailed information or a more stable formula over time, just let me know.

Thank you, Quantum! After 15 years of POIS treatment experiments, I have achieved fame (if not fortune) in Quantum’s POIS Types Chart.

An accomplishment!

[demografx]

In 2021…

Early 2022.

…Demografx added tadalafil 20mg ( Cialis) to his anti-POIS regimen. 

My Medical Group Pharmacist changed my Rx from 20mg to 10mg based on

• my age (76)

• my medical profile (surgeries, cardiac condition. other prescriptions, etc.)

[Quantum]

In 2021…

Early 2022.

…Demografx added tadalafil 20mg ( Cialis) to his anti-POIS regimen. 

My Medical Group Pharmacist changed my Rx from 20mg to 10mg based on

• my age (76)

• my medical profile (surgeries, cardiac condition. other prescriptions, etc.)

ok, I have updated the note in the chart.

[demografx]

ok, I have updated the [Cialis] note in the [POIS Types] chart.

Quantum, many thanks!

[demografx]

[For Demo’s testosterone + Cialis POIS treatment], if you get more detailed information or a more stable formula over time, just let me know.

Will do. And many thanks, Quantum, for your amazing thoroughness and dedication, in compiling POISCenter’s POIS Types Chart & POIS Treatment Methods!

[Quantum]

[For Demo’s testosterone + Cialis POIS treatment], if you get more detailed information or a more stable formula over time, just let me know.

Will do. And many thanks, Quantum, for your amazing thoroughness and dedication, in compiling POISCenter’s POIS Types Chart & POIS Treatment Methods!

Thank you !   I really think it is a must to keep track of all success members have in contrilling their POIS symptoms.

[Limejuice]

Prior to my testosterone treatment I tried Levitra, an erectile dysfunction med, a PDE5 inhibitor - - as an experimental treatment for my POIS.

It worked.

Then it eventually stopped working.

Luckily, I found testosterone, which I’ve been on for 11 years - - for POIS.

Today, I thought I’d give PDE5 another chance, so I tried Cialis, minimum dose. Too early to tell. If it doesn’t improve my POIS in Quantum’s suggested testing timeline, you won’t hear any more about it from me in this thread.

Best,
Demo

Quantum, it’s been 5 months since I posted this and - - after yesterday’s POIS-episode-and-Cialis-effective-treatment-supplementation, i hope we can add this to your POIS-types Chart & Treatment Methods.

Thank you,
Demo

My theory: Cialis speeds up POIS-induced refractory-period-sluggishness, which I think causes my POIS symptoms:

from Google search:
“Erectile dysfunction drugs called phosphodiesterase type 5(PDE5) inhibitors—which include meds like Viagra, Cialis, and Levitra—may also boost sperm quality in men whose swimmers aren't up to snuff, a new meta-analysis from China concludes.”
2017.

You've had intermittent success with Viagra in the past but has Cialis been a better PDE5?  Looks like Cialis lasts much longer than Viagra - maybe that's the difference?

[demografx]

You've had intermittent success with Viagra in the past but has Cialis been a better PDE5?  Looks like Cialis lasts much longer than Viagra - maybe that's the difference?

Levitra, never tried Viagra. But they’re identical, in my understanding of the two PDE5’s.

Interesting question, Limejuice!

1. Levitra (similar to Viagra) was intermittent, i think, because I experimented with it prior to my now-primary testosterone (TRT) POIS treatment.

2. Yes, Cialis has a much longer (36-72 hours’) range of effectiveness, and probably makes a significant difference.

And as Quantum mentioned, Cialis’ longer effectiveness span might make timing-for-POIS less important.

Thanks for asking.

[Limejuice]

Interesting that Cialis works for up to 72 hours and POIS episodes lasts for about the same duration (how long does POIS last for you on TRT?).

Glad you've found a second remedy that provides extra relief

[demografx]

Interesting that Cialis works for up to 72 hours and POIS episodes lasts for about the same duration (how long does POIS last for you on TRT?).

Glad you've found a second remedy that provides extra relief

Limejuice, my POIS lasts 1-2 days on TRT.

4 days in pre-TRT times. And symptoms were more intense.

[demografx]

After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

========================

This morning, POIS “struck”, and I followed my protocol above. I did not rest/stay in bed/force sleep and was busy with errands all day.

I have “miraculously” been POIS-free all day!!

Placebo effect? Time will tell!

Activity vs passivity was the only difference today.

Limejuice, Quantum, et al:
I’m continuing to have repeat success!

[demografx]

Does it work with thestosterone [sic] injections?

Sorry for the delay in responding, Didi, I only saw this just now.

My first endocrinologist was not in favor of injections, because they “spike” in and out of our systems.

On the other hand, testosterone patches or testosterone gel, he advised, provide a smoother, evenly, flow throughout the system, which mimics the way natural testosterone acts in the body.

I’ve been following this preference of his for testosterone administration for the last 11 years.

[demografx]

   


Video:
https://youtu.be/-KUfY0orf-E

Although Cialis is designed to treat ED (erectile dysfunction), as an off-label use it helps my POIS (as an augmentation to my TRT [testosterone] protocol).

I’m finding now that 5mg day(s) before and/or after POIS is better than 10mg or 20mg. The latter is too much of a “jolt” to my system, and increases sexual ideation, perhaps too much

[Limejuice]

Thanks for the update. Important dosage information as it seems too much could lead to more POIS. Glad your success continues.