Testosterone

[demografx]

I have been singing Benadryl’s praises for a long time to induce FORCED DAYTIME SLEEP, which miraculously lets me sleep through some of the worst initial POIS symptoms.

But you should be aware of some risks, e.g.,
Benadryl’s increased dementia risk
in this Harvard Medical School article:
https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-201501287667

If I’m reading the above correctly, Claritin might be a better choice.

[drop247]

Does anyone have a recommendation for a quality Tribulus supplement? I imagine so much of it out there is just junk.

[demografx]

Does anyone have a recommendation for a quality Tribulus supplement? I imagine so much of it out there is just junk.

“Despite marketing claims, Tribulus terrestris
does not appear to increase testosterone in humans. This conclusion is based on studies in men and women of various health statuses and ages.”
https://www.healthline.com/nutrition/tribulus-terrestris#TOC_TITLE_HDR_4

[berlin1984]

I'm recommending a specific brand in the Tribulus Terestris thread.
I have good experience with it as part of a stack with other supplements (see my signature).

Note that as demo said, Tribulus does not directly increase testosterone, but it has other effect (also on other hormones like LH apparantely) which help me.

Testosterone in general: Please also see BoneBroth's thread How to increase Testosterone naturally as going the prescription route is not feasible (doctor needed) or useful (fertility problems by TRT) for everyone.

In general I think a combination works best (pre-pack niacin and certain anti-histamine, post-pack testosterone booster and anti oxidant and anti inflammatory and adaptogens, lifestyle changes, don't masturbate but only have orgasm with a partner, ...), looking for a single chemical subtance might not work.. My life is now quite good and it only kills me if I masturbate :-/ Which can happen after a few days of abstinence.

[demografx]

I have been singing Benadryl’s praises for a long time to induce FORCED DAYTIME SLEEP, which miraculously lets me sleep through some of the worst initial POIS symptoms.

I use Benadryl as an adjunct to my TRT protocol, described above.

But you should be aware of some risks, e.g.,
Benadryl’s increased dementia risk is
reported in this Harvard Medical School article:
https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-201501287667

If I’m reading the above correctly, Claritin might be a better choice.

Right now, it’s 5:30am Saturday. I’m at POIS onset (“Day Zero”), and I just took an experimental 1,000 milligrams of Extra Strength Tylenol instead of Benadryl for POIS-onset-sleep-induction.





Plus I just took the POIS-onset-TRT (Testosterone Replacement Therapy) of 8mg - - a high dose for me.

TRT is not a recommendation or endorsement for other POIS sufferers. I am only reporting my own personal experiments & experiences. TRT has risks.


Wish me luck with Tylenol!! (That’s as scientific as I get this morning! )

[demografx]

...going the prescription [TRT] route is not feasible (doctor needed) or useful (fertility problems by TRT) for everyone.

berlin1984, thanks for pointing that out so succinctly!

[Iwillbeatthis]

I heard before that tylenol can lower your glutathione levels so be careful.

[Muon]

You could try Nitroglycerin demo, just once, see if you will get the same response as Testosterone:
https://poiscenter.com/forums/index.php?topic=3551.msg38085#msg38085

Edit: The nitroglycerin may synergize with TRT.

[demografx]

Iwillbeatthis, and Muon, thank you!

[demografx]

Wish me luck with Tylenol!! (That’s as scientific as I get this morning!

It worked!! But I’m also listening to Iwillbeatthis & Muon.

[Muon]

What worked the Tylenol?

Btw have you tried Nebivolol demo?

"I have done some research, and Nebivolol seems to be the one that has less side effects (it does not cause erectile dysfunction). It is as effective as Metoprolol. I think Demografx is taking metoprolol, so he can tell us if it's helping. I recommended him to switch to Nebivolol." Ref

[demografx]

What worked the Tylenol?

Yes! For early-POIS sleep induction.

Btw have you tried Nebivolol demo?

No. I’ll read up on your research. Thanks, Muon!

[demografx]

I think Demografx is taking metoprolol, so he can tell us if it's helping.

My cardiologist switched me to

• Carvedilol +
• Spironolactone +
• Amlodipine Besylate

[demografx]

I recommended [to Demografx] to switch to Nebivolol.

Muon, I sincerely appreciate the recommendation, but I would kindly remind you that our forum rule is that we do not make medical recommendations here. Even if someone in our forum is an MD, this is only between a patient and his/her own doctor. Better to say, “ask your doctor what s/he thinks of Rx - - -.

Many thanks for understanding!

[POIS1982]

Would love to go down this route but my doctor said let's start from scratch, let's put you on anti depressants lol ffs round and round the garden like a teddy bear

[Iwillbeatthis]

Would love to go down this route but my doctor said let's start from scratch, let's put you on anti depressants lol ffs round and round the garden like a teddy bear

Typical NHS doctors I assume, don't bother waste your time they are useless, either find a good specialist on the NHS or a good private specialist who knows about the areas related to POIS. But really GPS don't know anything and love to hand out antidepressants for everything like they are candy. Before sertraline I mainly just had issues in POIS, after sertraline usage I had chronic issues from food reactions to chronic brain fog, speech problems etc

[demografx]

I have been singing Benadryl’s praises for a long time to induce FORCED DAYTIME SLEEP, which miraculously lets me sleep through some of the worst initial POIS symptoms.

But you should be aware of some risks, e.g.,
Benadryl’s increased dementia risk
in this Harvard Medical School article:
https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-201501287667

After years of use/abuse, I’m now trying to
GET OFF BENADRYL.

Bad cognitive side effects...getting worse!

[demografx]

Cross-posted from
Vasodilatory for pois related tiny vessels spasm
https://tinyurl.com/ybqaktqu

Testosterone can increase dopamine via Nitric Oxide. Low T is a risk factor for endothelial dysfunction...

[demografx]

After years of use/abuse, I’m now trying to
GET OFF BENADRYL.

Bad cognitive side effects...getting worse!

Today is POIS Day Zero (POIS onset), and I didn’t take my usual dose of Benadryl to knock myself out to avoid experiencing early POIS symptoms. I simply was able to go back to sleep, wake up late, then
took 8mg TRT (high experimental dose) to counter early-POIS testosterone drop.

So far, so good!

[demografx]

Today is POIS Day Zero (POIS onset), and I didn’t take my usual dose of Benadryl to knock myself out to avoid experiencing early POIS symptoms. I simply
took 8mg TRT (high experimental dose testosterone patches) to counter early-POIS testosterone drop.

Instead of Benadryl I took 1,000mg of:


So far, so good!

This is NOT my endorsement or recommendation for anyone else with POIS to try! A good POIS treatment is between you and a trusted doctor. My preferred treatment can be unacceptably risky for many POISers.