Author Topic: Testosterone  (Read 185658 times)

demografx

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Re: Testosterone
« Reply #420 on: October 07, 2019, 01:41:42 AM »
Quantum (and others who wish to reply), I’ve been thinking of stopping TRT for a while, because it increases libido (as Quantum pointed out to me privately). And I think we all know what happens with POIS frequency when libido increases ;D

My past primary care physician (I have a brand new one now) said “there is no withdrawal from TRT”.

I’ve been on TRT-for-POIS for 10 years now and I’m curious whether my body, brain, mind and emotions have ‘normalized’ to the point where no-TRT will not necessarily plunge me into the same horror as 10 years ago.

Quantum, do you see a downside? (If the horrors come back, I assume that I could simply get back on TRT).

Thank you!
« Last Edit: October 07, 2019, 06:55:21 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

certainlypois2

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Re: Testosterone
« Reply #421 on: October 07, 2019, 02:53:09 PM »
Quantum (and others who wish to reply), I’ve been thinking of stopping TRT for a while, because it increases libido (as Quantum pointed out to me privately). And I think we all know what happens with POIS frequency when libido increases ;D

My past primary care physician (I have a brand new one now) said “there is no withdrawal from TRT”.

I’ve been on TRT-for-POIS for 10 years now and I’m curious whether my body, brain, mind and emotions have ‘normalized’ to the point where no-TRT will not necessarily plunge me into the same horror as 10 years ago.

Quantum, do you see a downside? (If the horrors come back, I assume that I could simply get back on TRT).

Thank you!

With the increased libido from testosterone can  you still live an almost pois free life.

demografx

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Re: Testosterone
« Reply #422 on: October 07, 2019, 11:06:04 PM »

With the increased libido from testosterone can  you still live an almost pois free life.


Not easily! That’s why I’m thinking of experimenting with stopping TRT for a while.
« Last Edit: October 08, 2019, 11:36:26 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #423 on: October 08, 2019, 05:27:59 PM »

...can  you still live an almost pois free life?


CP2, these days I’m not so sure about the “almost POIS free life” description. On Day Zero (POIS onset) and Day One I’m knocked out with extra TRT plus Benadryl. I feel “ok” but pretty groggy from all the extra sleep to minimize POIS symptoms. Plus lately I’ve noticed that I might feel “ok” on Day Zero and Day One, but...my personality changes. Sometimes? Hard to evaluate objectively!  For example, on my last round of POIS, in early Days I had a blowout argument with one of my sons. Not sure I would’ve reacted the same way in later days, e.g., in Days 3-4+

Anyway, I no longer suffer the 4-day POIS Horror Shows that I experienced 10 years ago. Plus, I’ve “aged into” no-NE’s. A blessing!
« Last Edit: October 08, 2019, 09:10:55 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Quantum

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Re: Testosterone
« Reply #424 on: October 09, 2019, 11:35:13 AM »
Quantum (and others who wish to reply), I’ve been thinking of stopping TRT for a while, because it increases libido (as Quantum pointed out to me privately). And I think we all know what happens with POIS frequency when libido increases ;D

My past primary care physician (I have a brand new one now) said “there is no withdrawal from TRT”.

I’ve been on TRT-for-POIS for 10 years now and I’m curious whether my body, brain, mind and emotions have ‘normalized’ to the point where no-TRT will not necessarily plunge me into the same horror as 10 years ago.

Quantum, do you see a downside? (If the horrors come back, I assume that I could simply get back on TRT).

Thank you!

Hi Demo,

It would worth a try, in my opinion.  Like I have said to you in private, TRT increases libido for sure, and this is no good for when we have POIS.

However, I do not agree with your MD that there is no withdrawal ( but, as you know, the opinions expressed here are not intended to replace medical advice and you will have to discuss it with a health professional).  You have been taking TRT for 10 years, so you own, endogenous production of testosterone is shut down for years.  If you stop at once, it will not revive instantly, and we need at least some testosterone in our body.  A progressive tapering of the dose is much more preferable, and you should discuss this with your specialist or primary care physician.

See https://www.nexelmedical.com/testosterone-therapy/can-you-stop-testosterone-replacement-therapy/ , it is a medical clinic suggesting progressive tapering to avoid emotional and physical sympoms.

The withdrawal for TRT is not as important as what someone may get from drigs acting on the central nervous system, like antidepressant, but they are to be considered as a possibility ( you will for sure read some horror stories on the net, but that's not the norm....).

Note that if someone stops could turkey, the possible emotional and physical symptoms can take some time to appear, when all T will have been eliminated from the body  ( there is a delay).   

A very slow tapering on several weeks or a few months would greatly help to manage any "surprise".
« Last Edit: October 09, 2019, 11:40:10 AM by Quantum »
You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

demografx

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Re: Testosterone
« Reply #425 on: October 09, 2019, 04:22:55 PM »

The withdrawal for TRT is not as important as what someone may get from drugs acting on the central nervous system, like antidepressant, but they are to be considered as a possibility ( you will for sure read some horror stories on the net, but that's not the norm....).


This reminds me: I’m on antidepressant Lexapro, so that might mitigate withdrawal symptoms.

ps - my past primary care physician comment about “no-withdrawal” was made - hastily - in a busy hallway while he was getting ready for his next patient. So there’s easily room for misunderstanding - - which makes me appreciate your considered reply even more. The same doctor also made a serious near-fatal misdiagnosis of another condition I had. He admitted the error. I didn’t sue, I just switched MD’s. World-famous doctor! But that doesn’t always guarantee great care! Everyone makes mistakes.
« Last Edit: October 10, 2019, 01:14:46 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #426 on: October 09, 2019, 04:28:42 PM »
Quantum, T H A N K   Y O U   very much!

This forum truly changed dramatically for the best under your moderation, administration and leadership!

My heartfelt congratulations,
Demo
« Last Edit: October 13, 2019, 06:41:41 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

certainlypois2

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Re: Testosterone
« Reply #427 on: October 09, 2019, 05:19:52 PM »
Quantum (and others who wish to reply), I’ve been thinking of stopping TRT for a while, because it increases libido (as Quantum pointed out to me privately). And I think we all know what happens with POIS frequency when libido increases ;D

My past primary care physician (I have a brand new one now) said “there is no withdrawal from TRT”.

I’ve been on TRT-for-POIS for 10 years now and I’m curious whether my body, brain, mind and emotions have ‘normalized’ to the point where no-TRT will not necessarily plunge me into the same horror as 10 years ago.

Quantum, do you see a downside? (If the horrors come back, I assume that I could simply get back on TRT).

Thank you!

Hi Demo,

It would worth a try, in my opinion.  Like I have said to you in private, TRT increases libido for sure, and this is no good for when we have POIS.

However, I do not agree with your MD that there is no withdrawal ( but, as you know, the opinions expressed here are not intended to replace medical advice and you will have to discuss it with a health professional).  You have been taking TRT for 10 years, so you own, endogenous production of testosterone is shut down for years.  If you stop at once, it will not revive instantly, and we need at least some testosterone in our body.  A progressive tapering of the dose is much more preferable, and you should discuss this with your specialist or primary care physician.

See https://www.nexelmedical.com/testosterone-therapy/can-you-stop-testosterone-replacement-therapy/ , it is a medical clinic suggesting progressive tapering to avoid emotional and physical sympoms.

The withdrawal for TRT is not as important as what someone may get from drigs acting on the central nervous system, like antidepressant, but they are to be considered as a possibility ( you will for sure read some horror stories on the net, but that's not the norm....).

Note that if someone stops could turkey, the possible emotional and physical symptoms can take some time to appear, when all T will have been eliminated from the body  ( there is a delay).   

A very slow tapering on several weeks or a few months would greatly help to manage any "surprise".

It will be a good time to try other remedies to see what works for you.

demografx

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Re: Testosterone
« Reply #428 on: October 09, 2019, 05:59:50 PM »
CP2, excellent idea!
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Quantum

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Re: Testosterone
« Reply #429 on: October 11, 2019, 09:37:15 PM »

Quantum, T H A N K   Y O U   very much!

This forum truly changed dramatically for the best under your moderation, administration and leadership!

My heartfelt congratulations,
Demo

Thank you , Demo !
« Last Edit: October 13, 2019, 06:41:05 AM by demografx »
You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

Vandemolen

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Re: Testosterone
« Reply #430 on: October 23, 2019, 05:18:59 PM »
Something weird happened. In my latest test my testosterone was 29! In the last 10 years it was always around 10. But I took those previous tests in the afternoon. The latest test I did was at noon. I know there is a difference between a test in the morning and the afternoon. But so big?
I did a new blood test. My testosterone was 15. 50% less than the last time. But within the normal range of my hospital: 10-30. I will go next month to my urologist to talk about the result.
POIS since 2000. Very bad since 2008. I knew that I have POIS since June 2010. Desensitization since March 2011. I stopped with desens in July 2016. I have 50% less POIS. And only 1 day of POIS. Purified CBD works for me, but I am allergic for CBD.

demografx

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Re: Testosterone
« Reply #431 on: October 24, 2019, 09:51:47 PM »
Day Zero. No POIS today!

;D I must be dreaming ;D
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

b_jim

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Re: Testosterone
« Reply #432 on: October 29, 2019, 03:17:28 PM »
It seems testosterone stimulates Gaba transmission :
https://www.ncbi.nlm.nih.gov/pubmed/14769394

Taurine = Anti-Pois
Suffering from lyme disease

Nas

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Re: Testosterone
« Reply #433 on: October 29, 2019, 03:42:12 PM »
It seems testosterone stimulates Gaba transmission :
https://www.ncbi.nlm.nih.gov/pubmed/14769394
Wait so Testosterone increases GABA neurotransmittion?

demografx

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Re: Testosterone
« Reply #434 on: October 31, 2019, 10:49:08 PM »


Dr. Petr Weiss, Czech Republic sexologist. I phoned him around 2008, told him I was in total agony & desperation with POIS, could he recommend anything? He said, “You need testosterone!”. I was *very* skeptical...over the phone? But after seeing several local urologists and an endocrinologist, I thought, “What do I have to lose?” It hasn’t been a total cure, but it’s helped. A lot.

My treatment story. No science! :)
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business