Testosterone

[demografx]

Thanks for the update. Important dosage information as it seems
too much [Cialis] could lead to more POIS.

Glad your success continues.

Bold emphasis mine - - Demo

Many thanks, Limejuice!

[demografx]

   


Video:
https://youtu.be/-KUfY0orf-E

Although Cialis is designed to treat ED (erectile dysfunction), as an off-label use it helps my POIS (as an augmentation to my TRT [testosterone] protocol).

I’m finding now that 5mg day(s) before and/or after POIS is better than 10mg or 20mg. The latter is too much of a “jolt” to my system, and increases sexual ideation, perhaps too much

One possible theory: TRT+Cialis stimulates my semen production, thereby facilitating the speed of my refractory period recovery.

I’ve long thought that my refractory period sluggishness is possibly implicated in my POIS symptoms.

[demografx]

Out of all the many medical specialists I consulted since the 1970’s, endocrinologists are the only medical professionals who have significantly helped my POIS. For the last 12 years.



Has anyone tried this service? I called them once for
online endocrinology advice to supplement my periodic visits with my regular endocrinologist.

I didn’t continue after the “test”. I found another endocrinologist to work with. In person.

So I can’t yet “rank” them as good or bad.

JustAnswer Endocrinology:
https://tinyurl.com/2p8seujy

[Limejuice]

   


Video:
https://youtu.be/-KUfY0orf-E

Although Cialis is designed to treat ED (erectile dysfunction), as an off-label use it helps my POIS (as an augmentation to my TRT [testosterone] protocol).

I’m finding now that 5mg day(s) before and/or after POIS is better than 10mg or 20mg. The latter is too much of a “jolt” to my system, and increases sexual ideation, perhaps too much

One possible theory: TRT+Cialis stimulates my semen production, thereby facilitating the speed of my refractory period recovery.

I’ve long thought that my refractory period sluggishness is possibly implicated in my POIS symptoms.

Seems like a plausible explanation. Perhaps the process of creating semen is extensive and taxing to the body.  Or maybe the body of POISers lack the ease of producing semen.   Either way the fact that the combination of these supplements reduce your symptoms is great!

[demografx]

   


Video:
https://youtu.be/-KUfY0orf-E

Although Cialis is designed to treat ED (erectile dysfunction), as an off-label use it helps my POIS (as an augmentation to my TRT [testosterone] protocol).

I’m finding now that 5mg day(s) before and/or after POIS is better than 10mg or 20mg. The latter is too much of a “jolt” to my system, and increases sexual ideation, perhaps too much

One possible theory: TRT+Cialis stimulates my semen production, thereby facilitating the speed of my refractory period recovery.

I’ve long thought that my refractory period sluggishness is possibly implicated in my POIS symptoms.

Seems like a plausible explanation. Perhaps the process of creating semen is extensive and taxing to the body.  Or maybe the body of POISers lack the ease of producing semen.   Either way the fact that the combination of these supplements reduce your symptoms is great!

Many thanks for your input, Limejuice!

[demografx]

From July 30, 2022 with UPDATE today, February 18, 2022



After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

=============================

This morning, POIS “struck”, and I followed my protocol above. I did not rest/stay in bed/force sleep and was busy with errands all day.

I have “miraculously” been POIS-free all day!!

Placebo effect? Time will tell!

Activity vs passivity was the only difference today.

========
My UPDATE:
========



February 18, 2023
Also *my* 16th Anniversary
at this forum:

***It’s still working for me***
Thank you fellow-forum-members!

[demografx]

[MY OWN, PERSONAL POIS HYPOTHESIS]

• The feeling I have is that my own POIS is somehow connected to the sluggish speed of my recovery/ refractory period.

• It seems that my symptomatic improvements stem from hastening the speed of my refractory period. I think that both Cialis and testosterone help this by stimulating semen movement.

I also think there’s a well-documented drop in testosterone upon POIS onset/orgasm, so a higher-than-normal dosage of TRT & Cialis is immediately used to offset this effect.


From July 30, 2022 with UPDATE today, February 18, 2022


After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

=============================

This morning, POIS “struck”, and I followed my protocol above. I did not rest/stay in bed/force sleep and was busy with errands all day.

I have “miraculously” been POIS-free all day!!

Placebo effect? Time will tell!

Activity vs passivity was the only difference today.

========
My UPDATE:
========



February 18, 2023
Also *my* 16th Anniversary
at this forum:

***It’s still working for me***
Thank you fellow-forum-members!

[Progecitor]

[MY OWN, PERSONAL POIS HYPOTHESIS]

• The feeling I have is that my own POIS is somehow connected to the sluggish speed of my recovery/ refractory period.

• It seems that my symptomatic improvements stem from hastening the speed of my refractory period. I think that both Cialis and testosterone help this by stimulating semen movement.

I also think there’s a well-documented drop in testosterone upon POIS onset/orgasm, so a higher-than-normal dosage of TRT & Cialis is immediately used to offset this effect.


From July 30, 2022 with UPDATE today, February 18, 2022


After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

=============================

This morning, POIS “struck”, and I followed my protocol above. I did not rest/stay in bed/force sleep and was busy with errands all day.

I have “miraculously” been POIS-free all day!!

Placebo effect? Time will tell!

Activity vs passivity was the only difference today.

========
My UPDATE:
========



February 18, 2023
Also *my* 16th Anniversary
at this forum:

***It’s still working for me***
Thank you fellow-forum-members!

If anyone wants to pursue such a theory should know that an analogous phrase for the refractory period is post-ejaculatory interval (PEI). PEI is one component of the sexual behavior that aphrodisiacs may positively regulate. Some herbs specifically found to reduce PEI are Devil's beggartick, White goosefoot, White sapote, Mucuna pruriens, Camel thistle, nutmeg, African basil, Tribulus and Damiana, but probably many of the other aphrodisiacs do so.
https://www.researchgate.net/profile/Dr-Satyendra-Prasad-2/publication/257746737_Pharmacologically_screened_aphrodisiac_plant-A_review_of_current_scientific_literature/links/5f12ac8492851c1eff1ba4ab/Pharmacologically-screened-aphrodisiac-plant-A-review-of-current-scientific-literature.pdf

Testing GABAA agonists and antagonists could be worthwhile as well.
However, there is a consistent body of evidence showing that GABA and drugs with GABAergic effects, have an inhibitory effect on male sexual behavior in the rat and this may be particularly significant during the postejaculatory refractory period when levels of GABA in the CSF are raised. Stimulation of presumed GABAA receptors in the MPOA decreases the number of animals mounting and intromitting whereas blockade of GABAA sites decreases the post-ejaculatory interval.
http://imop.med.auth.gr/sites/default/files/bancroft1999.pdf

[demografx]

Thank you, Progecitor, for your additional insights into my personal-POIS hypothesis!

[Hopeoneday]

Testosterone experts, do man can hawe low testosterone although i
hawe a so strong beard, chest hair, body hair, i mean my body hawe
no sings of low testasterone, like man boobs , high voice etc?

[demografx]

https://youtu.be/-KUfY0orf-E

Prior to my testosterone treatment I tried Levitra, an erectile dysfunction med, a PDE5 inhibitor - - as an experimental treatment for my POIS.

It worked.

But then it stopped working.

Luckily, I found testosterone, which I’ve been on for 11 years - - for POIS.

Today, I thought I’d give PDE5 another chance, so I tried Cialis, minimum dose. Too early to tell. If it doesn’t improve my POIS in Quantum’s suggested testing timeline, you won’t hear any more about it from me in this thread.

Best,
Demo

It’s been over a year since I wrote the above. Now taking Cialis DAILY (365 days/year). It improves my POIS symptoms.

My NEW POIS doctor (his clinic sees some “selective” POIS patients) also recommends taking this [italicized paragraph below] combination - see below L-Citrulline graphic  - every morning.

His clinic’s protocol (for patients like me) is to take 3,000mg of L-Citrulline plus 5mg Cialis
D A I L Y (365 days). Plus my DAILY testosterone replacement therapy (TRT)

In accordance with Quantum’s 3-week trial before posting recommendation, I’ll wait till then for posting my POIS-reaction to L-Citrulline.

[Hopeoneday]

I wonder, is all man who hawe lower end testosterone hawe
pois symptomes to?
https://www.reddit.com/r/POIS/comments/13xibmq/trt_and_gonadorelin_cured_most_of_my_symptoms/

[demografx]

After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

=============================

My new POIS doctors (medical team) convinced me to switch from TRT daily patches to TRT injections weekly.

Have appointment soon to receive
.5 mL/100mg Testosterone Cypionate (Pfizer)

[demografx]

After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

My new POIS doctors (medical team) convinced me to switch from TRT daily patches to TRT injections weekly.

Have appointment soon to receive
.5 mL/100mg Testosterone Cypionate (Pfizer)

My POIS symptoms are further improved. First weekly testosterone injection was yesterday.

But I will follow Quantum’s Three Week Rule:

“If you have found a treatment which seems to work very well to alleviate your symptoms and are dying to tell everyone about it, respect our three week rule. If you think you have found a treatment, make a short announcement that you think you have found something very useful, but that you will respect the three week rule before describing the treatment to others. The reasons for this are many-fold: the success you perceived may have been circumstantial, give the procedure time to prove itself, the treatment may only work for you and only in certain conditions and we don't wish to raise false hopes with our members unnecessarily.”

[demografx]

My current testosterone reading (from yesterday) with injections vs readings with TRT patches:

6/16/2023 10:21 PM
Component   Value   Ref Range & Units   Status
Testosterone   316   200 - 1,000 ng/dL   Final

April 18, 2023 (my new POIS doctors)
348

March 17, 2022 (with endocrinologist)
248

July 23, 2021 (with endocrinologist)
187

March 17, 2021 (with endocrinologist)
114


After 11 years of TRT (Testosterone Replacement Therapy): it’s still disappointing to be at the
LOWER END of the normal range!

Any thoughts?
======================

Update to the above
Googling TRT levels by age, maybe it’s not so low after all! (I’m in my 70’s):

Testosterone levels in 40s: 252–916 ng/dL
Testosterone levels in 50s: 215–878 ng/dL
Testosterone levels in 60s: 196–859 ng/dL
Testosterone levels in 70s: 156–819 ng/dL

From:
“Normal Testosterone Levels by Age”
https://tinyurl.com/ym6wjd67

[demografx]

After 15 years’ experimentation, this (above) is what I do for my POIS treatment. Effectiveness for me: sometimes, nearly completely POIS-free. Some episodes are “better” than others.

Major disadvantage: POIS Day Zero (the first day when POIS actually onsets)
is - - often but not always - - spent resting and/or in bed. I use Tylenol PM to force more sleep.

CPAP machine (last image above) aids oxygenation.

I am still working on
• timing,
• dosages, and
• prior abstinence required
in conjunction with the combination pictured above

INFERTILITY ALERT: as a result of my
Testosterone-for-POIS treatment, my sperm count went to 0.00!

So if you’re planning a family (I already had children before my testosterone-induced sperm loss) decide wisely. With a doctor. I prefer an endocrinologist.

My new POIS doctors (medical team) convinced me to switch from TRT daily patches to TRT injections weekly.

Have appointment soon to receive
.5 mL/100mg Testosterone Cypionate (Pfizer)

My POIS symptoms are further improved. First weekly testosterone injection was yesterday.

But I will follow POISCenter’s Three Week Rule:

I’m a few days’ short of 3-weeks, but I wanted to report today because I had a POIS Episode just yesterday.

Yesterday’s POIS onset is much improved symptomatically (yesterday & today) - - over my typical experience!

I’m certain it’s due to nearly 3 weeks of testosterone weekly intramuscular injections (plus daily low-dose Cialis plus daily 3,000 mg L-Citrulline) vs. daily transdermal patches. I have been applying the latter protocol since the year 2009.

Since I’m still on the low side of testosterone levels for my age (77), I asked for and received approval for a higher dose on Thursday of this week, my next scheduled injection.

[demografx]

Since I’m still on the low side of testosterone levels for my age (77), I asked for and received approval for a [50%] higher dose on Thursday of this week, my next scheduled injection.

With yesterday’s POIS, I experienced meaningful recovery after just four (4) hours! - - which included a very brief dozing off/nap.

Big breakthrough for me!

But it’s only 3 weeks. After 3 months, I’ll ask Quantum to please include my
weekly testosterone high-dose injections in his POIS Treatment Methods Chart!

[demografx]

Since I’m still on the low side of testosterone levels for my age (77), I asked for and received approval for a [50%] higher dose on Thursday of this week, my next scheduled injection.

With yesterday’s POIS, I experienced meaningful recovery after just four (4) hours! - - which included a very brief dozing off/nap.

Big breakthrough for me!

But it’s only 3 weeks. After 3 months, I’ll ask Quantum to please include my
weekly testosterone higher-dose injections in his POIS Treatment Methods Chart!

It’s been about 3 weeks since I wrote this and my weekly testosterone higher-dose injections continue to significantly improve my POIS recovery time (vs. my daily transdermal testosterone patches since 2010).

[demografx]

I’m vacationing for the month of August, so my new POIS doctors prescribed this for
self-injecting my testosterone while traveling! (No nurse required )

I thought I was too fearful to self-inject, but this is sooooo easy & 100% painless, safe & foolproof!!

And no, I’m not an advertising spokesperson for the product!

[demografx]

Since I’m still on the low side of testosterone levels for my age (77), I asked for and received approval for a [50%] higher dose on Thursday of this week, my next scheduled injection.

With yesterday’s POIS, I experienced meaningful recovery after just four (4) hours! - - which included a very brief dozing off/nap.

Big breakthrough for me!

But it’s only 3 weeks. After 3 months, I’ll ask Quantum to please include my
weekly testosterone higher-dose injections in his POIS Treatment Methods Chart!

It’s been about 3 weeks since I wrote this and my weekly testosterone higher-dose injections continue to significantly improve my POIS recovery time (vs. my daily transdermal testosterone patches since 2010).

• The above protocol

plus

• 

continue to effectively alleviate my POIS.

Quantum, it’s now about 3 months