Progesterone

[FloppyBanana]

Hi LAPOISSE,
I have continued to take Noritheristerone and there has been no noticeable bad side effects.It seems that I need to take more than average over a period of 4 days to have no symptoms. For one O I have to take 6 tablets over 4 days (2,2,1,1 amounts each day). (2 O's 8 tablets 6 days). I asked Dr Dexter how it works and he has no idea. It seems so strange to me that neurosteroid can prevent all the symptoms I get all over my body. The brain fog is the most distressing and noritheristerone stops it for me. I tried taking less than 6 tablets per O a few times and I get a headache which is like nothing I have ever experienced before. I have to avoid taking caffeine when on the medication as well, otherwise I feel restless for days. I still only have sex once or twice every 3 weeks.

Apparently this drug is safe to use for a person in good heath between the age of 18-70. I had to sign a document to say that I take my life in my own hands basically when using the medication. I still very cautious about take the medication too much.
FloppyBanana

Hi All,
This is a small update from my experience of using Norithisterone (NT) (Progesterone). I have a few bad POIS spells and NT didn't stop the aching and tiredness. I have used NT for 6 nearly 6 months now. One of the side effect of NT for me was that it made me feel cold2 to 5 hours after taking. As a consequence I only take NT before I go to bed and this seems to be working. I have found the strenuous physical exercise really does cause my POIS to get very much worse. Apparently there are POISers out that that can benefit from physical exercise. This is certainly not me. One positive effect of NT is that for me it stopped the profuse pissing & Sh*t*ng after O. This markedly reduces POIS in its self. Even though I still feel tired from POIS when taking NT my appetite is not affected and stays healthy. With no NT all food quickly gets ejected from my body and appetite is very low for 2-3 days. In my above post I stated that NT reduces POIS symptoms by 90%. I would like to revise this to 70%. When I first went to Dr Dexter he advised I had two options, NT or Antihistamine (levocetirozine). I rejected the Anti H because I was told that it had a diuretic effect.

I have just start both of the above remedies. So, when I O now I take 2 NT at point of O (most usually evening) then one tablet before bed for 4 days after. Also I am taking one levocetirozine in the morning for 3 day after O. I will update on my progress in the near future of taking both of these. I hope this posts helps someone out there.
Regards - Floppy B

[FloppyBanana]

One things I should have mentioned is that taking NT doesn't mean I can drink coffee within 7 days of O. Coffee still absolutely kills me with 7 days of O.
FB

[FloppyBanana]

Below is an illustration in chart format (click on link to enlarge) of the effect of me taking progesterone versus not taking it. This is all based on my own personal experience. I actually take the first progesterone tablet an hour before orgasm, the second after. I have found that the benefit of progesterone is the appetite is strong and healthy while taking it. Also it seems to stop my bowel disruptions. Kicking off a POIS cycle (most symptoms 7 days approx) is bad when you have diarrhoea and no appetite. One side effect of taking progesterone is that it can make me very cold. I remedy this my mostly taking it before I go to bed and that works fine.

[demografx]

Norethisterone made me sick for 4 days, so I quit.

[FloppyBanana]

Norethisterone made me sick for 4 days, so I quit.

Taking progesterone will lower testosterone levels in the short term. I had a blood test 2 days after finishing the usual 5 day course for one O.
Dr advised that he expects progesterone to reduce testosterone for a while. The test results confirmed this. I took another blood test when I had not taken progesterone for over a week and it had returned to within the healthy range. My Doc advised there are other drugs which reduced testosterone and this included treatments for male pattern baldness. When taking male pattern baldness medication testosterone reduces and returns to normally levels afterwards when stop taking the medication. I guess we just don't know if progesterone could affect testosterone levels adversely for long periods of time or permanently. I expect POIsers with causal factor being low testosterone could have a bad experience with the testosterone lowering effect progesterone can have, in my limited understanding.

You never know perhaps progesterone could have the side effect of preventing baldness. It would be good if my bald patch didn't get any bigger!
FB

[Daveman]

Norethisterone made me sick for 4 days, so I quit.

Taking progesterone will lower testosterone levels in the short term. I had a blood test 2 days after finishing the usual 5 day course for one O.
Dr advised that he expects progesterone to reduce testosterone for a while. The test results confirmed this. I took another blood test when I had not taken progesterone for over a week and it had returned to within the healthy range. My Doc advised there are other drugs which reduced testosterone and this included treatments for male pattern baldness. When taking male pattern baldness medication testosterone reduces and returns to normally levels afterwards when stop taking the medication. I guess we just don't know if progesterone could affect testosterone levels adversely for long periods of time or permanently. I expect POIsers with causal factor being low testosterone could have a bad experience with the testosterone lowering effect progesterone can have, in my limited understanding.

You never know perhaps progesterone could have the side effect of preventing baldness. It would be good if my bald patch didn't get any bigger!
FB

At one point, when the allergy to sperm theory was a little stronger, we contemplated a progesterone/testosterone combination which had shown successful as a male contraceptive, because it controlled testosterone which stopped sperm production temporarily. The idea was to stop production of the "offending component".

Tests never went very far for all of the "uncomfortable" side-effects. Progesterone is a female's hormone, although present in the male in lower quantities.

[himanshu]

Hi V,
I don't know where to start with that question. I have to summarise it I'm afraid. I have read the study papers and some of the sharings on this forum and I can relate to nearly all of what people experience (remedy side effects aside). I have not had a swollen lip (allergic reaction) after O like one person though. One thing which I have which I have not noticed other people share about is the effect of CAFFEINE. If I have caffeine with 7 days of O I feel really sick (headache, empty feeling around stomach). After the 7 days I can carry on drinking coffee again. Cardiovascular exercise seems to have a similar problem within the 7 days.  I have had bad symptoms in the last 5 years of Diarrhea (within this 7 day period). So in summary Diarrhea, muscle fatigue and cognitive impairment are the main symptoms which leads to an all round confused and frustrated person.

I don't like the idea of taking Progesterone long terms but at present there is no other option to relieve symptoms unless I abstain. I was advise by a Doctor that one patient had taken Progesterone for 2.5 years. This leads to guess it is most likely the person who is referred to in the study paper dated 2010. We do not know what the long terms effects could be.
Sorry for not providing a complete assessment but even after an hour speaking with a Doctor I felt like I was only touching the iceberg of 24 years of POIS (since puberty).

I would interested if there any other people who are the same type as me or similar: NOT allergic to semen, progesterone relieves PIOS, and has PE, PPOIS symptoms last 7 days. I would like to know what remedies these similar people have tried and there progress.
All the best - FB

hi guys.. im a doctor ..jst like u i have sufferred from pois for past 4 years.. i have lost very gud career opportuniti​es,friends and even gud grades because of this...to cure it i tried nicotine..d​idnt work then i tried ginko biloba..did​nt work...then i tried norethreste​rone...it wrked a littlle bt i was not sure about the right dosage..i starded with higher doses..taki​ng 200mg perday it used to decrease the symptops but they would cm back again...fin​ally i have found a regime that works here it is.....take 10mg of norethreste​rone within minutes of orgasm...th​en keep urself on a mainatainan​ce dose of 5 mg every 2 to 3 hrs for 2 days...for those who have cognitive dysfunction during pois like me...u will feel way better...be​lieve me..my theory is that we jst have to prevent the sharp fall in progesteron​e levels afet aorgasm...i​f the brain does not fall short of progesteron​e supply....n​othng happens..:D:D

[FloppyBanana]

Hi himanshi,

I missed your post in September and have just seen it now. It is interesting that you are doctor and have POIS. Managing to become a Doctor passing your exams and having POIS is no small feat! 200mg per day sounds like quite a lot to take per day. I have just increased my dosage from 6 tablets (5mg) to 7 tablets per O over a 5 day period and noticed a big improvement.

Have you had any adverse side effect from taking the amount you have? How long did it take you to build up to that amount? When did you first get prescribed Progesterone?
Which Progestin do you take? I take Norithisterone. My Doctor (Dr Dexter who wrote a POIS paper) advised me that there other progestins out there and they have different half lives among other things. I may try a different type of Progestin in January and see how that goes. Dr Dexter did advise that the person in his paper tried another type of progestin but it didn't work.

Have you had blood and sperm test while taking progesterone?
Thanks! FB

[Daveman]

Hi himanshi,

I missed your post in September and have just seen it now. It is interesting that you are doctor and have POIS. Managing to become a Doctor passing your exams and having POIS is no small feat! 200mg per day sounds like quite a lot to take per day. I have just increased my dosage from 6 tablets (5mg) to 7 tablets per O over a 5 day period and noticed a big improvement.

Have you had any adverse side effect from taking the amount you have? How long did it take you to build up to that amount? When did you first get prescribed Progesterone?
Which Progestin do you take? I take Norithisterone. My Doctor (Dr Dexter who wrote a POIS paper) advised me that there other progestins out there and they have different half lives among other things. I may try a different type of Progestin in January and see how that goes. Dr Dexter did advise that the person in his paper tried another type of progestin but it didn't work.

Have you had blood and sperm test while taking progesterone?
Thanks! FB

Thanks Floppy, Dr. Dexter is a good POIS doctor!

[POISrival]

I tried synthetic progesterone(Northisterone) and It really helps especially with the mental effects of POIS.

[FloppyBanana]

Drmmeha,

Glad to hear the good news! You are only the third person I am know of that have had success with Norithisterone. Are you close enough to New Jersey to be part of the research?

Thanks - FloppyB

[b_jim]

I think dr Dexter chose an elegant way to analyze Pois and he made a good work with progesterone for his patients.

[POISrival]

Drmmeha,

Glad to hear the good news! You are only the third person I am know of that have had success with Norithisterone. Are you close enough to New Jersey to be part of the research?

Thanks - FloppyB

Thanks FloppyB. Unfortunately no, I live in Egypt.

[amsterdam]

I think the progesterone discussion is dead. I believe progesterone has always been a hoax. I tried it and got worsen pois. I tried it just a vew times but got panic about worser pois .

Is there any one that has result?

I have a conversation with my doctor this morning about Testosterone. I am a bit irritated aout the big difficulty to find quick good information here and a disis to begin with . its also such long tread!!  Maybe mr. Daveman should write a summary.  so people that are new here can see quick information.

David.

[G-man]

Progesterone is affective at combatting nocturnal emissions for me. I tend to get nocturnal emissions on nights where I forget to apply the cream before bed.