I suffered from POIS with all the symptoms that you can find in
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome at least 10 years.
It got worst the first years and then it was the same difficult situation, having to wait 4 days to feel better, not this thing like an "explosion" in the body after the ejaculation. I remember 2012 I ve discoverd this forum and I was with a girl then, and after ejaculation I was dead...what to explain and who could take me seriously because it is rare and people think that we are exagerating and that everyone feels a bit tired after ejaculation. Doctors have no idea.
But believe me last two weeks symptoms disapeared. One Day 10 days ago I ejaculated on purpose 4 times. (I am 38 years)
I believe the therapy came from Classical Homeopathy, the homeopathic doctor found my "charachter" (Lycopodium for me, but for each one is different) and by the fact that I dont drink coffee, that it has been a long time since I used antiinflamator drugs, the time has come (after 10 years of homeopathy, changed several doctors) with the last doctor we came to a solution.
One more thing that I have done last month, started Ayurvedic medicine (taking one pill and one spoon of a powder in the night)
I took off amalgam fillings from a tooth too.
That's alll, Keep taking multivatamin, saw palmeto, and a good nutrition, no sugar, no bread, no pasta...
I stoped also a but habit of trying to stop ejaculation when it came out, now when it come out I try to empty. (It is not good to try to stop ejaculation when it happens)
Miracle but true,
I am looking forward to keep alll good tratments.