Poll

Do you suffer of Premature Ejaculation ? (PE)

Yes, severe PE  (even before penetration)
12 (15.2%)
Yes, normal PE
42 (53.2%)
No
25 (31.6%)

Total Members Voted: 73

Author Topic: Premature ejaculation  (Read 20047 times)

Starsky

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Re: Premature ejaculation
« Reply #20 on: March 07, 2014, 03:43:54 PM »
Check your copper levels. Most of POISers have low ceruloplasmin which is bioavaliable copper. Low copper=high histamine.  I am working to have more bioavailable copper and so far i have good results.

My ceruloplasmin levels were 0,13 Range 0,20-0,60.

I reached now 0,21.

I did not take copper. It seems that i had copper stored in tissues which is really disturbing on the body.

This is the histamine metabolism. You need copper to produce DAO. If you have good amounts of copper and still high histamine than its a methylation issue. But please check your copper in blood.

« Last Edit: March 07, 2014, 03:49:17 PM by Starsky »

Stef

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Re: Premature ejaculation
« Reply #21 on: March 07, 2014, 10:13:22 PM »
Hi, Slugishdragonn (and everyone else!),

It's great to hear that you're feeling better on your current regimen. POIS is such a miserable, awful condition. When something actually helps -- it's like a miracle has occurred! I don't say that lightly.

As you stated, you're doing several different things to find some relief -- neem (an herb -- I'm not clear about what it does), regular exercise, magnesium supplements, cromoglicic acid ("cromylyn" in the US --  an over-the-counter mast cell inhibitor that is used to treat allergies and asthma).

It could be that the combination of therapies -- or even just one -- is helping you. There's no way to know what's providing the relief.

The most important thing is that you're being followed by your physician...this can't be emphasized enough!!

We're all wishing you the best of luck!

As an aside, Starsky -- there's no research or documentation, anywhere, reflecting that men with POIS have low ceruloplasmin levels.  This is a theory that some forum members subscribe to -- but it is not fact. It might be worthy of formal scientific research at some point.

Stef   





b_jim

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Re: Premature ejaculation
« Reply #22 on: March 10, 2014, 05:20:38 AM »

My ceruloplasmin levels were 0,13 Range 0,20-0,60.

I reached now 0,21.



Does it really improve your pois symptoms ?
Taurine = Anti-Pois
Suffering from lyme disease

slugishdragonn

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Re: Premature ejaculation
« Reply #23 on: March 10, 2014, 01:07:22 PM »
Hi all,
thanks for your replies.

My entire regime seems to help just accelerate the Histamine excretion.
However, I still do feel POIS symptoms after Orgasm. I suspect the Auto Immune reaction still exist, whenever I ejaculate the body histamine level increases and after taking Magnesium, Methionine, Neem, Calcium, Vitamin C the Histamine level comes down waiting for the Orgasm to start it all over again !

By the way, I also feel pain in my Hands and Legs during sex (Even before ejaculation... when my Penis is erect and I get pleasure vibes).
I could imagine it to be my prostate, which is inflammed (due to exposure of semen all this long), and on erection/ejaculation, it is squeezed/tensed whatever, and the pain trickles all through the limbs.

Do you guys experience the same pain ?
I also have pain in mild pain in my lower back on the day of Orgasm.

Your expereinces/views are higly appreciated.

Thanks in advance.
slugishdragonn
POIS since Puberty, Y2K. Chronic gingivitis, brain fog, UTI, PE.
Tested +ve with skin prick test.

berlin1984

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Re: Premature ejaculation
« Reply #24 on: May 24, 2020, 01:51:53 PM »
Cross posting:

Premature ejaculation seems to be very common in the 'nofap' community, so it might be a general body (mal)adaption and not related exclusively to POIS.

Taking Tryptophan, 5HTP or Slow-Release 5HTP can help some people with premature ejaculation. It's also a side effect of SSRIs (anti depressants).

I've also seen that the above amino acids can help a bit with slow transit contipation.

berlin1984

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Re: Premature ejaculation
« Reply #25 on: June 07, 2020, 10:20:05 AM »
See also this thread:

* During an orgasm, histamine is released, and has been connected to the sex flush among women. However, men with high histamine levels may suffer from premature ejaculations.

And this one:
...
My thought: Person consumes too much histamine via food and also histamine liberators. Has problems with DAO (histamine intolerance). Has leaky gut, making histamine passing through to bloodstream. Then: Histamine is released at orgasm. Virus is somehow re-activating and does it's thing, maybe involving more histamine.
All this histamine overload leads to problems.
...

Muon

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Re: Premature ejaculation
« Reply #26 on: August 02, 2020, 10:19:39 AM »
See also this thread:

* During an orgasm, histamine is released, and has been connected to the sex flush among women. However, men with high histamine levels may suffer from premature ejaculations.

Glans Penis Augmentation Using Hyaluronic Acid Gel for the Treatment of Premature Ejaculation

Guess what, HA inhibits histamine (from mast cells)
https://sci-hub.se/https://www.sciencedirect.com/science/article/pii/S0161589008000151

Mast cell mediated premature ejaculation?

Association of NE, leptin, and 5‐HT with electrophysiological parameters in patients with primary premature ejaculation
« Last Edit: August 02, 2020, 12:30:16 PM by Muon »

Iwillbeatthis

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Re: Premature ejaculation
« Reply #27 on: February 16, 2021, 02:03:26 PM »
When I last had sex a few years ago I had premature ejaculation before penetration even, I was also under the influence of alcohol. The times I've had sex since I devoloped POIS I've had premature ejaculation every time, apart from one time where I wasn't drinking alcohol - this time the first the first O was premature however the second O wasn't.

Before I had POIS my experience was that the more times I had sex the premature ejaculation got better every time which is the case with most men who have PE.

Now I can't tolerate alcohol at all so maybe I won't have PE the next time I have sex.

If you have PE issues cutting out Porn is probably the most helpful thing you can do. Porn is instant gratification which messes up the circuits in your brain causing PE.
« Last Edit: February 16, 2021, 02:53:40 PM by Iwillbeatthis »

Cursed

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Re: Premature ejaculation
« Reply #28 on: February 17, 2021, 04:45:30 PM »
How quick is Premature Ejakulation? 2 minutes? Davemen did you have that problem before POIS?

Strangely, when I tend to be most sensitive, I can't hardly even get it up, yet just about anything will set it off.

If I'm really "hot" and "hard" (excuse the graphic nature), I will usually last longer.

Weird huh?

I feel exactly the same. In fact, it's very strange that sometimes I feel that I just need to masturbate because I have this feeling of stimulation, even though I have no erection unless I actually start masturbating and then I would finish very quick. Also, this isn't really real horniness, I think it's more similar to what's called restless genital syndrome or something like that. I get this often the next day after ejaculation. Then it goes away.

At leaat for me, it is all depends very much on what I eat and how my GI tract is doing, but I haven't found anything that really works. I'm playing around with fecal transplants, hoping to fix the microbiome.

To add: these symptoms got better after I began using taurine, b2, b6, TMG, zinc,selenium and occasionally some methylfolate.
« Last Edit: February 17, 2021, 04:56:18 PM by Cursed »

VSmasher

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Re: Premature ejaculation
« Reply #29 on: July 15, 2021, 05:45:52 PM »

well if you guys are still interested on the PE topic.
From my research, what I understand is following:
1. The allergen in the semen, causes the Mast cells to release histamine.
2. This histamine builds up over time in our body causing inflammations. I have gingivitis, sinusitis, UTI, Acne and nerves.
3. Histamine is also responsible for vasodilation of capillaries.
4. Histamine quickens ejaculation/reach orgasm. Some doctors prescribe histidile tablets to women who cant reach orgasm.
5. People with low histamine have difficulty reaching orgasm.

If that is true, than most likey people who have Positive skin prick test, must be experiencing PE.
For myself, I have positive and PE.. 5-10 strokes in and am set off :(

Any thoughts on this ?

Cheers,
slugishdragon

You can have high histamine WITHOUT having an allergic reaction. Histamine is used in your body for a ton of natural daily reactions. For instance, your body histamine increases in the morning to wake you up. (I think that's why I cum so quick with morning sex). Also, you don't need mast cells to release histamine. Your brain makes histamine inside the CNS as it acts as a neurotransmitter. You can have no mast cell release of histamine, and still have high brain histamine. I agree 100% that brain histamine may be our problem though.
My POIS Symptoms:  Brain Fog, frustration, stuffed nose, anger, anxiety, intense hunger, low self esteem, swollen face, and feel zoned out.

VSmasher

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Re: Premature ejaculation
« Reply #30 on: July 16, 2021, 02:14:42 PM »

well if you guys are still interested on the PE topic.
From my research, what I understand is following:
1. The allergen in the semen, causes the Mast cells to release histamine.
2. This histamine builds up over time in our body causing inflammations. I have gingivitis, sinusitis, UTI, Acne and nerves.
3. Histamine is also responsible for vasodilation of capillaries.
4. Histamine quickens ejaculation/reach orgasm. Some doctors prescribe histidile tablets to women who cant reach orgasm.
5. People with low histamine have difficulty reaching orgasm.

If that is true, than most likey people who have Positive skin prick test, must be experiencing PE.
For myself, I have positive and PE.. 5-10 strokes in and am set off :(

Any thoughts on this ?

Cheers,
slugishdragon

Also, Opioids like oxycotin stop me from having an orgasm. Opioids release tons of histamine. Maybe our histamine is to low..?
My POIS Symptoms:  Brain Fog, frustration, stuffed nose, anger, anxiety, intense hunger, low self esteem, swollen face, and feel zoned out.

Muon

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Re: Premature ejaculation
« Reply #31 on: July 20, 2021, 06:52:12 AM »
Note that a couple of women here with POIS suffer from premature orgasm.