My successful experience with Pregabalin and Propanolol Hydrochloride

[POISrival]

Hello everyone! I hope you are doing good and never admitting defeat to POIS.

I have been trying Pregabalin and Propanolol Hydrochoride for around three weeks now. I would like to tell you more about my experience with it.
But PLEASE PAY ATTENTION TO:
1- THOSE TWO DRUGS HAVE SERIOUS SIDE EFFECTS ESPECIALLY IF TAKEN WITH LARGE DOSES
Pregabalin is an anticonvulsant drug.
Propanlol Hydrochloride is a beta blocker used to treat Circulatory disorders like Hypertension (Overdosing can lead to severe hypotension)
so BE CAUTIOUS

2- DONT TAKE THEM TOGETHER IN THE SAME TIME OR THE SAME DAY (IM NOT SURE IF ITS SAFE)

3- DONT TAKE THOSE DRUGS UNTIL YOU CONSULT YOUR DOCTOR

4-IF YOU HAVE ANY DISORDER (ESPECIALLY IF CIRCULATORY, RESPIRATORY or NERVOUS), DONT TAKE THEM UNLESS YOU CHECK WITH YOUR DOCTOR

5- PROPANOLOL HYDROCHLORIDE IS CONTRAINDICATED IF YOU ARE HYPOTENSIVE OR YOU HAVE ASTHMA
    PREGABALIN IS CONTRAINDICATED IF YOU HAVE G6P DEFIECIENCY

6-THEY MAY HAVE BAD EFFECTS ON THE LONG RUN . WITHDRAWAL FROM PROPANOLO HYDROCHLORIDE CAN BE PAINFUL IF YOU USED IT FOR LONG TIME.

7- I have noticed that POIS is a personal disease. aside from the cognitive symptoms, It is different from an individual to another. I dont know what the mechanism of action of those drugs is on POIS. They might be just masking the bad effects of POIS. I cant guarantee if they are gonna work for you.




So, How different did those two drugs make my life?


Well, First of all. My POIS is chronic. by that, I mean that I developed chronic effects. I'm always nervous and stressed out (not only after Orgasm, but of course they get more severe after it), I always have memory problems. I even can't enjoy things!! I usually feel down and depressed after orgasm, but in the regular days, I feel nothing, not excited! I can't enjoy stuff. Sad news don't move my feelings either. I don't easily cry when something so sad happens. However, sometimes, I get attacks of depression  (in the regular days) with no specific reasons that I want to cry so bad and feel that I have to be more nice to people because life is so miserable to everyone (Thats how I think at those times).
I also noticed that I get fatigude easily without the urge to rest. I would know I'm fatigued but I'm thrilled to work more (may be It has something to do with the  stress I suffer from)

Now, after using those two drugs, I feel better progressively. They arenot magic that changed my life  in one day. But, I'm less stressed in a noticable way. I'm nice to people even after Orgasm. even my family noticed it! My father asked me If i started smoking weed  
I practice swimming, I suddenly started to function better! My stamina changed in a noticable way too.
My attention span hasn't changed significantly tho to be honest. BUT, It is getting better slowly. for the first time in almost three years, I could read a whole short story and enjoy it!!

The trademarks of the drugs I used is Averopreg for pregabalin and Inderal for Propanlol Hydrochloride.

How often do I take those medications?

I take one pill of pregabalin 50mg 2-3 hours before I go to sleep. It helps me sleep comfortably.
then on the next day, I take Propanolol Hydrochloride (I take small doses on the regular days, Like 2.5mg) and when I want to have an orgasm (I increase the dose a little to 5mg)
I have read some reviews about it, proplanolol hyrdoclhoride is used to treat stress in small doses. I have also noticed that repsonse to this drug varies from person to another. so you can start with 2.5 mg and increases gradually but I dont advise you to take more than 10mg. It can cause asthma and severe Hypotension.
I dont take them on the same day. I swtich from one drug to another on a daily basis.

I'm not planning to use them on a regular basis like im doing now. Once I get rid of the chronic effects, I think I will be using them only when I'm willing to have orgasm

Do I do other stuff that helps?

Yes, I drink Green tea a lot and I have been practicing swimming for 6 months.




I hope they work for you like they did for me.
Don't hesitate to ask any question or to talk about your doubts. I'm open to criticism  


My best regards,
Mmeha

[Jmari]

The Beta blocker connection is interesting. Just over the past month I have this feeling that POIS might be related to circulatory or a heart condition. When I was younger, I actually had times when I experienced tachycardia and weakness after work outs. I went to the hospital, where a cardiologist performed a stress test and a cardiogram but found nothing abnormal. He gave me a prescription for a beta blocker which I decided not to take. I shrugged it off. A year later, I started experiencing POIS. Before, I would always flush in the face after orgasm, later it morphed into POIS. I am not trying to jump to conclusions but the possibility exists.

[POISrival]

The Beta blocker connection is interesting. Just over the past month I have this feeling that POIS might be related to circulatory or a heart condition. When I was younger, I actually had times when I experienced tachycardia and weakness after work outs. I went to the hospital, where a cardiologist performed a stress test and a cardiogram but found nothing abnormal. He gave me a prescription for a beta blocker which I decided not to take. I shrugged it off. A year later, I started experiencing POIS. Before, I would always flush in the face after orgasm, later it morphed into POIS. I am not trying to jump to conclusions but the possibility exists.

The flushing part is interesting to me! the last two times I had an Orgasm I flushed (during and after) and my whole body was so warm.

[Jmari]

you said you take the beta blocker(propranolol hydrochloride) on a daily basis. How long have you been doing this and has it significantly reduced symptoms? I plan to return to the cardiologist that I saw three years ago and ask him about a prescription and what he thinks of this whole thing. For me, there are other symptoms that might hint at a cardiovascular anomaly rather than the "allergy theory."

[POISrival]

you said you take the beta blocker(propranolol hydrochloride) on a daily basis. How long have you been doing this and has it significantly reduced symptoms? I plan to return to the cardiologist that I saw three years ago and ask him about a prescription and what he thinks of this whole thing. For me, there are other symptoms that might hint at a cardiovascular anomaly rather than the "allergy theory."

It has been around 21 days since I started both drugs. One day, I take the beta blocker. the other day, I take the pregabalin. Some days, I take both, but If i do, It is the beta blocker in the EARLY morning and pregabalin before I go to sleep. I dont take them together because there was one night I did and I felt so exhausted physically afterwards.

Yes, Taking those drugs has reduced it a lot. Usually when I have an Orgasm, I feel so bad afterwards that I keep thinking of it for two days. Last time I had an Orgasm, I totally forgot I had one 30 minutes after.
 POIS certainly affects my cardiovascular system. Sometimes, Orgasms causes me epistaxis. It also causes alternations in my blood pressure.
 I had my heart checked three years ago and it was normal. May be the doctors missed something. I'm going to get it checked again soon.

[Jmari]

How were you able to persuade your doctor about Inderal?

[sameer7777]

I also think have same thing , took inderal till 40 mg two years back ...... But nothing helps
I also think its heart problem
Thats why i did echo and all came ok really disappointed with .
The only oher symptoms i get is my nostril get blocked and i get tinnitus and head is heavy very heavy
Thanks

[POISrival]

How were you able to persuade your doctor about Inderal?

I didn't because where I live, you can buy 99% of medications without prescription.

[POISrival]

I also think have same thing , took inderal till 40 mg two years back ...... But nothing helps
I also think its heart problem
Thats why i did echo and all came ok really disappointed with .
The only oher symptoms i get is my nostril get blocked and i get tinnitus and head is heavy very heavy
Thanks

It's bad news it didnt work for you.
I have read from another POISer that NSAIDs+Beta blockers helped him too. May be it has something to do with the timing (I take inderal one hour before orgasm). or May be it's the pregabalin that's effective for me.
I think POIS is chain of events where the circulatory changes is a main event that leads to many other symptoms, however it's not the TOP event(main cause).
I get nose bleeding sometimes, phonophobia and feeling of pressure in my head especially when I bend down or do any position that increases blood flow to my head

[sameer7777]

Thanks i will try imderal again !!!

[kuba]

My main symptom of pois is heart beating fast. But my heart is normal and pois causes it to beat fast after orgasm.

[Jmari]

So I started taking Inderal, the  doc prescribed 60 mg ER. This is not something I should mess around with

[sameer7777]

i will try pragblin what does should i take and what side affects i could get ......

and inderal gives low blood pressure so i stop it ....

[POISrival]

My main symptom of pois is heart beating fast. But my heart is normal and pois causes it to beat fast after orgasm.

Probably Inderal will help you.

So I started taking Inderal, the  doc prescribed 60 mg ER. This is not something I should mess around with

I'm glad your doctor agreed to prescribe it. I hope it helps you. Please, Post your feedback when you done trying it for sufficient time.

i will try pragblin what does should i take and what side affects i could get ......

and inderal gives low blood pressure so i stop it ....

Pregabalin(aka Lyrica) is an anticonvulsant drug. It has a lot of side effects(Including pyschological changes such as suicidal thoughts), so please be cautious. You should check side effects with your doctor AND do a good search about it on google.
I used to take a 50 mg pill before I go to sleep and it helped me feel less irritable and get a good sleep. It makes me wake up euphoric and with greater appetite (It is one of its "side effects")