How did POIS start for those who got it in adulthood(not in puberty) ?

[Daveman]

Hello everyone, I'm 35 years old and my pois began less than a year.
It started when I tried to cure prostatitis that brought me problems for years and no one could tell what it was, with great depression on my part. I have been prescribed many antibiotics and other drugs that have ruined my intestines. At that time I also developed a terror to the act of masturbation, because I had to ejaculate inside a jar for spermioculture and then for fear of damaging even the prostate. After a short time, I began to lose semen, normally even sitting down. From that point, I began to have flu-like symptoms the day after ejaculation.
So, to summarize, in my case, the factors are possible:
Super Stress and Nervousness
antibiotics
Fear in the sexual

P.S. as I had never taken care of this little infection probably from a young age, when antibiotics have cleaned my semen, they have been able to change the its composition, causing him to be foreign to the body today .... but it's just a guess.
The doctors do not understand anything about this, figured if I can find out.
Greetings to all!

There's another possibility, that you have had POIS for longer than you think. Perhaps the prostatitis (that no one could really figure out or cure) was really POIS. For many, POIS may start much before you actually realize that the symptoms are related to ejaculation. And it would be even more complicated if it was hidden by thinking it was prostratitis.

Also some of us have ended up with POIS due to operations or damage in the area. Mine coincides closely with a vasectomy reversal (the POIS increased and became evident several years after the surgery.

[Nas.Car]

Thanks Daveman,
indeed my fear is that the inflammation of my prostate is an effect of this intolerance to my semen later that year, is coming out.
The only thing that comforts me is with abstinence do not have flu symptoms.

I also add that I have low testosterone and LH and FSH levels below the normal, there is definitely something wrong even in my pituitary gland .. Hopefully one day we will be able to understand what happens in our body.
Best Wishes!

[Daveman]

My guess (un-educated) is that you've probably had POIS for many tears, but they've treated you for everything else because nobody knows what POIS is.

As I said, I had a vasectomy reversal, after 20 yrs of vasectomy. My POIS effects all the "ducting" from the gonads up to the seminal vessels. Everything swells down there including my prostate for the days of POIS.... at least before I discovered niacin.

Then in about 10 days, everything returns to normal. (If I make it that long without sex.)

So you say you "leak", without any sexual arousal, and that alone causes POIS?

Inasmuch as I reject the desensitization theory, we can't have allergy to our own semen, I believe we can "react to it", but more as an autoimmune reaction than an allergic reaction.
This would explain at least the cases like ours where there may have been some injury or plumbing problems that permits sperm to "go where it shouldn't".

And although the end result may be the same (in terms of symptoms), the solution and process is not at all the same.

[Nas.Car]

Excellent point of view, Daveman.
Doctors should investigate on what changes in seminal fluid as it enters the urinary tract. This could help to compare the values ​​of certain substances of a "normal" man and a "pois" man.
Greetings.

[Progecitor]

I forgot to say that I developed POIS shortly after receiving a vaccine for Tuberculosis.  The one that bubbles up on your skin to let doctors see if you have a reaction.  Anybody else relate?  Or is it just a coincidence.  I also think I've read somewhere that vaccines can trigger an auto-immune problem.

I don't know if there could be a connection, but I also developed POIS around the time of the Mantoux test. I was at the age of 12 at the time, however I began to masturbate at the age of eleven, but I can't recall if I had any symptoms at the time. I certainly remember some symptoms from the age of 12 or 13 though. I also had some cases of "overmasturbation" (5-6 times a day) around the same age, so I really don't know what could have contributed the most to POIS development. Regarding the Mantoux test I got the shot in my shoulder and I remember the site was filled with pus for several weeks and the wound often opened up while bathing. Based on what you say it was probably a normal reaction though. The information in the vaccine pass is the following:
1997. 05. 09.: BCG – Mtx 5TU negative, Re BCG: "973", 1997. 09. 09.: Scar: positive.
I am not really sure how this should be interpreted. According to wikipedia if the second shot proved positive it means that there was an infection in the distant past. However the real question is whether the test shot itself could have induced POIS onset or if it is a pure coincidence that POIS tends to develop around the same age as this test is scheduled.
https://en.wikipedia.org/wiki/Mantoux_test

[Journey]

I forgot to say that I developed POIS shortly after receiving a vaccine for Tuberculosis.  The one that bubbles up on your skin to let doctors see if you have a reaction.  Anybody else relate?  Or is it just a coincidence.  I also think I've read somewhere that vaccines can trigger an auto-immune problem.

I don't know if there could be a connection, but I also developed POIS around the time of the Mantoux test. I was at the age of 12 at the time, however I began to masturbate at the age of eleven, but I can't recall if I had any symptoms at the time. I certainly remember some symptoms from the age of 12 or 13 though. I also had some cases of "overmasturbation" (5-6 times a day) around the same age, so I really don't know what could have contributed the most to POIS development. Regarding the Mantoux test I got the shot in my shoulder and I remember the site was filled with pus for several weeks and the wound often opened up while bathing. Based on what you say it was probably a normal reaction though. The information in the vaccine pass is the following:
1997. 05. 09.: BCG – Mtx 5TU negative, Re BCG: "973", 1997. 09. 09.: Scar: positive.
I am not really sure how this should be interpreted. According to wikipedia if the second shot proved positive it means that there was an infection in the distant past. However the real question is whether the test shot itself could have induced POIS onset or if it is a pure coincidence that POIS tends to develop around the same age as this test is scheduled.
https://en.wikipedia.org/wiki/Mantoux_test

I too had that Mantoux test but I do not remember when exactly I first developed POIS symptoms I just recall around ages of 14-15 noticing that each time I ejaculated I had this off feeling but I only abstained long enough when I was 17 to make the clear connection between orgasms/ejaculations/nocturnal emissions and my POIS symptoms

[Warrior]

I know this thread is a bit old, but I thought it was a good/interesting question to answer anyway.

I developed (unknowingly) POIS around age 17. Took me a decent period of time to realize it was POIS/orgasm related. I don't know what caused it. Eating food overseas (in Vietname I did eat a lot of strange food lol)? Vaccines in highschool? All the shitty food I was stuffing myself to try to gain muscle? Back injury? Medication for fungal toe? So many factors, I have no idea.

[BoneBroth]

Were you submitted to much psychological stress the years before you were 17 years old?

[Warrior]

Were you submitted to much psychological stress the years before you were 17 years old?

I would say not at all. I was a very extraverted and naturally confident kid (POIS made me experience social anxiety for the first time really in my entire life, though I've made some really solid progress back into my old confident state). I grew up in a healthy household, with 2 good parents (not perfect but I'd say better than most probably). The psychological stress I can only really assume began when POIS started. I was also smoking a lot of pot at the time, so it was a terrible combination. Maybe the psychological stress began independently, and then POIS followed, but I doubt it. There was nothing for me to stress about in my life really, apart from the odd thing here and there. I can remember a few specific events that did cause a lot of stress, but they seem normal and only lasted a couple of days (nothing too crazy).

[OpiesDad]

My POIS emerged spontaneously when I was 39. Until then I had a very normal social life and sex life.  Going on four years and the condition is well controlled by medications, diet and lifestyle changes.  I believe there's a chance that the condition was originally triggered in part by a few years of reasonably indulgent use of a certain white powder that may have messed with my neurochemistry.  That's just a wild guess though.  Anyways, it was incredibly frightening and puzzling when symptoms first emerged, then resolved, then re-emerged with seemingly no rhyme or reason, until I made the connextion that it was related to orgasm.  Thought I was dying... Then I found this site and my mind was blown.

[Warrior]

I think theres a good chance POIS is autoimmune, at least in my case.

There are 3 factors/events that create autoimmunity that I learn about in the book The Paleo Approach by Sarah B.
1) the right genes
2) environmental toxin
3) leaky gut

Maybe all 3 just came together one day. My diet certainly wasnt amazing, so the leaky gut isnt a far stretch at all. Nothing you can do about genes, and in terms of environmental toxin, this could be literally anything including viruses, exposure to chemicals, etc, which is bound to happen. Then with a bit of bad luck, it is the perfect storm for autoimmunity to develop.

[Warrior]

Happen to look through my immunisation history today. Came across 2 vaccines I was administered at school the year I suspect my POIS began:

15 May 2017 Meningococcal ACWY Menactra
29 Dec 2017 Hepatitis A Typhoid Vivaxim

Pretty sure my POIS began around the beginning of 2018 (ish). Tbh it's very difficult to pinpoint the exact date, but a ballpark memory would honestly be the beginning of 2018.

Ultimately I don't know if any of these vaccines played a key role in starting my POIS, but I cringe at the possibility that it did (as an environmental toxin, a key ingredient for autoimmune diseases developing).

Obz not a doctor or specialist, so this is just speculation.

Now that I think of it, I can't believe ive basically lived with this for 4-5 years. Completely uprooted my entire life, self esteem, mental-health, etc. I will say that since finding my POIS solution, I have managed to turn most of it all around, and am on a good path upwards.

[Mushnikk]

I think my POIS began after a period of extreme psychological stress

[StressPOIS]

It started during a period when I was in extreme emotional stress. I was also dehydrated (didn't drink water for days),  and I was also masturbating excessively during this period. I was also not sleeping properly.

[freddie]

old thread, but very interesting, so this is my story:
I am 52 now, my pois started approx. 10 years ago. during these years the symptoms escalated and became more long-lasting, at present some symptoms may have become permanent.
I associate the onset of pois with a period when I watched porn and masturbated more frequently than usual.
Earlier than that I had also had another period when I had more sex than usual and I was puzzled by long-lasting flu-like symptoms. 
Another thing that may have played a role is that I removed amalgams from my teeth. that can have caused mercury poisoning.
for more info about mercury poisoning look at this thread:
https://poiscenter.com/forums/index.php?topic=3203.msg49130#msg49130