Yesterday I took methyl b12 1000mcg , alpha gpc 500mg and b6 25mg and I got really bad knee pain with a little feet pain. I also had some brain fog. After this I took 200mg of Sam-e to try and make things better. Then I wake up the day after and my back is in complete agony. Now I am unsure if this is from a bad back stretch in yoga or the supplements i took but I have read about choline causing back pain.
The thing is I've taken 1200mg choline a day with no problems so I think this is all down to the methyl b12 interacting with the alpha gpc. Could anyone give me a better explanation on why these two gave me such a bad reaction?
Obviously I won't take this combination ever again...