Cognitive POIS doubt

[Unvers]

Hi all, recently I am developing on my own the idea that cognitive POIS that involve symptoms like drowsiness, impaired concentration, foggy brain and the like can be because of an intolerance to opioids, recently I am studying oppioids like heroin and methadone who consumers claims have effects very similar to an orgasm and I am watching their adverse effects on the mind rather than the body and many are the same of cognitive POIS, I don't know at which point is official research on cognitive POIS but this finding seems to me very logical because is well know that orgasm release endogenous oppioids in the brain.

[b_jim]

Lot of us think at least one neurotransmitter is deficient after orgasm.
But which one(s) is it ? That is the question 

[Unvers]

Lot of us think at least one neurotransmitter is deficient after orgasm.
But which one(s) is it ? That is the question 

Dopamine is antagonized by orgasm even in healthy individuals, maybe is serotonin.

[Unvers]

I am more and more convinced of my POIS being a withdrawal syndrome to the opioids neurotransmitters released with orgasm, it resemble a bit nicotine abstinence, never been on opiods withdrawal but is the only logical conclusion I found because without orgasm even if I had pre ejaculation I don't have POIS symptoms apart a light fall in dopamine caused by prolactin after a while that is normal I think.