my POIS is way more manageable since I got my diet dialed. I eat tons of salt when I'm in a POIS state, 2 tablespoons in a cup of water and i sip that all day. This had a major effect on the intensity of the symptoms. Extra cholesterol (saturated fat, not poly unsaturated which is extremely oxidizing and can cause insulin resistance) converts to pregnenolone which then converts to steroid hormones, this helps keep stress down. Sugar also has protective properties on cells during stress, so i put extra sugar and cream in my coffee. Aspirin helps inflammation. Look into Ray Peats work, the guy is a genius and his work seriously helps POIS.