I have not had a bad episode of POIS for many months.
Congrats, kurtosis!
"Many months" is extremely promising.
It is and it's
genuine but I've modified the Kurtosis method quite a bit since I first talked about it. I stopped various supplements to see which worked the best. I did so because I've changed my view of how to deal with my own symptoms and decided that the cold hands and other symptoms that seem like a thyroid issue are related to POIS.
I've given up on krill oil for a while. The last batch I got smelled awful and I think the product is just too variable. The health food shop says I could get less variability for twice the price. Well, it would need to 100% cure POIS to pay twice the price for krill oil
If you want the anti-inflammatory effect of prawns or krill then just take astaxanthin. It's cheaper and less variable.
I use a lot of coconut oil during the day. I'm no longer very cold.
I'm only using the b complex vitamins every 2nd day and half the dose (1 tablet). They never made me feel sick but there's vitamins in the muscle milk naturals so why take more.
Apart from the lecithin in Muscle Milk I'm trying to remove all soya from my diet. I've also cut down dramatically on gluten. I've been wonder about glutamate sensitivity and orgasms. I've wondered whether the memory wipe was the result of excito toxicity of some neurotransmitters (e.g. glutamate)
See
http://www.jneurosci.org/content/26/6/1699.fullAnd similar comments about vision problems due to excessive NE and glutamate.
http://cure-erectile-dysfunction.org/vision-problems-eye-floaters-and-sexual-activityI'm not suggesting that we're having excessive O's, I'm just saying that the symptoms of POIS including fatigue, inability to concentrate and eye problems occur with other NORMAL people when they have too much sex.
I wondered whether we might have a
glutamate decarboxylase deficiency (leading to too much glutamate following an O) but the treatment is b6 or active b6 which I''m already taking... It's possible that this treatment only works when the glutamate decarboxylase deficiency is due to b6 deficiency or malabsorption. See analysis at
http://www.biopku.org/pdf/gaba_diag.pdfThis disease is normally spotted in childhood but it's interesting to imagine that there may be a variant such that the synthesis of glutamic acid decarboxylase in the liver is not so low as to lead to childhood epilepsy but too low to cope with the demands of an orgasm, which really pushes the body to deal with excess glutamate like something not experienced before.
It's an interesting idea as, if POIS is related to glutamic acid decarboxylase deficiency, it may have a genetic marker in some sufferers. Some variation in the genes for GAD expression...
Excess glutamate after an O (without it being adequately converted to GABA) could lead to a tonne of problems including over anxiety, tremors, excess norepinephrine and stress hormones etc. The sufferer would also be very sensitive to MSG. Again, it's an interesting theory as some of us have noticed "chinese food syndrome" when we get too much MSG. Decreased GAD expression leads to schizoid symptoms and it's possible that there's a spectrum of glutamic acid to GABA conversion illnesses rather than just those that don't have it and those that obviously have a problem because they have seizures from a young age.
http://www.ncbi.nlm.nih.gov/pubmed/22036037I still take ginkgo 120mg every day.
I still take the carnitine complex every day. Studies show that acetyl l-carnitine increases dopamine levels and promotes neurogenesis. Either way, I like it and I feel better when I take it.
I'm taking pregnenolone. I had to remember what it was like. Great is the answer. I'm taking it 5 times a week. I'll stop in another few weeks but not for long.
Pregnenolone is potentially a good treatment for excess glutamate leading to nervous system excitotoxicity.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573207/In the interests of full disclosure, I also take piracetam for my eye condition (nystagmus). The eye condition is probably brought about by POIS. Its benefit is consistent with an excess glutamate and diminished GABA theory.
I have no memory holes nor trouble thinking. I may try that Russian noopept as it's even stronger than piracetam. A software programmer I know picked some up over the counter while in Moscow. He said it was fascinating. It's incredibly cheap over there.
The biggest problem that I had with POIS was losing my memory, particularly of things I've learned since POIS got worse a few years ago. I'm happy so long as that isn't a problem. I don't care that much about "flu like symptoms". I can cope with the flu but I can't cope with having to relearn complex textbooks after an O or 2.