I developed POIS when I was 16. I have got first antibiotic when I was 18. Before that I never ate them. The anthibiotics that I've got when I was 18, cured my POIS for 2 years. Nobody understood how this was possible... Nobody knew I had POIS. Doctors just gave me anthibiotic Ciprofloxacin, becouse they had no idea what is wrong with me. When they gave me Ciprofloxacin again when I was 22, it coused me the strongest paine I've ever felt in my life. Killing paine lasted for one year and left me damage I can feel even today (I am 33).