One forum member, Animus, I believe, actually had his testicles removed, his seminal vesicles cauterized, and his prostate surgically reduced in size. His symptoms disappeared completely afterwards, so long as he adhered to his meds.
I personally wouldn't mind, though I'd imagine most POISers would find this option somewhat undesirable.
Hi Bombardier, and everyone,
About Animus, since he has not posted on the forum for about 6 years now, it is hard to say anything about long term efficiency of the radical choice he made. We do not know if he is still 100% cleared of POIS. I never had the chance to be in contact with him, since I have found this forum 4 years ago.
It seems, however, that having his testicles removed was linked to a personal condition - I think he had a painful lump or something similar, and the orchidectomy did not contribute significantly to his POIS relief. This concurs with the reports from members who went through vasectomy, saying that it didn't bring any relief for their POIS.