For now I treat my cognitive POIS with a neurointegrator with B3, caffeine and nicotine at low dosage, nicotine at low dosage is a stimulant while the majority of addicts use it as sedative but an individue with POIS doesn't need to be sedated but rather stimolated, I use nicotine also as antidepressant and use it by smoking, I know it is dangerous but I noted that the effect are major in comparision at nicotine gum and I decided to take the risk, nicotine is also very addictive and discontinuing it cause a withdrawal syndrome who resemble cognitive POIS infact some doctors think that POIS itself is a withdrawal syndrome to opioids released by orgasm so cognitive POIS can be compared in the cognitive symptoms to withdrawal from opioids like heroin and methadone.